PIPA5121265
Phospho-Tau (Thr205) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5121265-Each-of-1 | In Stock | ₹ 43,079.46 |
PIPA5121265 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,079.46
GST (18%): ₹ 7,754.303
Total Price: ₹ 50,833.763
Antigen
Phospho-Tau (Thr205)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MAPT
Gene Alias
AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17762
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
2.63 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
P10637
Gene Symbols
MAPT
Immunogen
A synthetic phosphorylated peptide around T205 of human Tau (NP_001190181.1).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Mouse
Product Type
Antibody
Isotype
IgG
Description
- Positive test controls include: Mouse brain
- The target is usually found in the following locations: Cell membrane, Cell projection, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, axon, cytoskeleton, cytosol
- Immunogen sequence: PGTPG Tau is a neuronal microtubule-associated protein found predominantly on axons
- The function of Tau is to promote tubulin polymerization and stabilize microtubules
- The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both
- Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome
- The short isoforms allow plasticity of the cytoskeleton while the longer isoforms may preferentially play a role in its stabilization
- In its hyper-phosphorylated form, Tau is the major component of paired helical filaments (PHF), the building block of neurofibrillary lesions in Alzheimer's diseases (AD) brain
- Hyper-phosphorylation impairs the microtubule binding function of Tau, resulting in the destabilization of microtubules in AD brains, μgtimately leading to the degeneration of the affected neurons
- Numerous serine/threonine kinases phosphorylate Tau, including GSK-3beta, protein kinase A (PKA), cyclin-dependent kinase 5 (cdk5) and casein kinase II
- Hyper-phosphorylated Tau is found in neurofibrillary lesions in a range and other central nervous system disorders such as Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Compare Similar Items
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Antigen: Phospho-Tau (Thr205)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAPT
Gene Alias: AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17762
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 2.63 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: P10637
Gene Symbols: MAPT
Immunogen: A synthetic phosphorylated peptide around T205 of human Tau (NP_001190181.1).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Tau (Thr205)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAPT
Gene Alias:
AI413597; AW045860; DDPAC; FLJ31424; FTDP17; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; map tau; Mapt; MAPTL; MGC138549; microtubule associated protein tau; microtubule-associated protein tau; microtubule-associated protein tau, isoform 4; microtubules; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; neurofibrillary tangles; Neuronal Marker; paired helical filament-tau; PHFtau; PHF-tau; PPND; PPP1R103; protein phosphatase 1, regulatory subunit 103; pTau; RNPTAU; Tau; Tau microtubule-associated protein; tau protein; Tau-4; Tau5; Unknown (protein for MGC:134287)
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17762
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
2.63 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
P10637
Gene Symbols:
MAPT
Immunogen:
A synthetic phosphorylated peptide around T205 of human Tau (NP_001190181.1).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-Cofilin (Ser3)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CFL1
Gene Alias: 18 kDa phosphoprotein; AA959946; CFL; Cfl1; CFL-1; Cof; COF1; cofilin; cofilin 1; cofilin 1 (non-muscle); cofilin 1, non-muscle; cofilin, non-muscle isoform; Cofilin1; Cofilin-1; cofilin-1-like protein; epididymis secretory protein Li 15; HEL-S-15; n-cofilin; p18
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1072, 12631, 29271
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.06 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: P18760, P23528, P45592
Gene Symbols: CFL1
Immunogen: A synthetic phosphorylated peptide around S3 of human CFL1 (NP_005498.1).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Cofilin (Ser3)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CFL1
Gene Alias:
18 kDa phosphoprotein; AA959946; CFL; Cfl1; CFL-1; Cof; COF1; cofilin; cofilin 1; cofilin 1 (non-muscle); cofilin 1, non-muscle; cofilin, non-muscle isoform; Cofilin1; Cofilin-1; cofilin-1-like protein; epididymis secretory protein Li 15; HEL-S-15; n-cofilin; p18
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1072, 12631, 29271
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.06 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
P18760, P23528, P45592
Gene Symbols:
CFL1
Immunogen:
A synthetic phosphorylated peptide around S3 of human CFL1 (NP_005498.1).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-LCK (Tyr505)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LCK
Gene Alias: EC 2.7.10.2; Hck-3; IMD22; kinase Lck; Lck; LCK proto-oncogene, Src family tyrosine kinase; Lck1; Lcktkr; leukocyte C-terminal Src kinase; LSK; Lskt; Lsk-t; Lymphocyte cell-specific protein-tyrosine kinase; lymphocyte protein tyrosine kinase; lymphocyte-specific protein tyrosine kinase; OTTHUMP00000008640; OTTHUMP00000008740; OTTHUMP00000008741; p56(LSTRA) protein-tyrosine kinase; p56<lck>; p56lck; p56-LCK; pp58lck; Protein YT16; Proto-oncogene Lck; Proto-oncogene tyrosine-protein kinase LCK; RP4-675E8.4; t cell-specific protein-tyrosine kinase; T-lymphocyte specific protein tyrosine kinase p56lck; tyr; tyrosine-protein kinase Lck; YT16
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3932
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: 0.88 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.: P06239
Gene Symbols: LCK
Immunogen: A synthetic phosphorylated peptide around Y505 of human Lck (NP_001036236.1).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-LCK (Tyr505)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LCK
Gene Alias:
EC 2.7.10.2; Hck-3; IMD22; kinase Lck; Lck; LCK proto-oncogene, Src family tyrosine kinase; Lck1; Lcktkr; leukocyte C-terminal Src kinase; LSK; Lskt; Lsk-t; Lymphocyte cell-specific protein-tyrosine kinase; lymphocyte protein tyrosine kinase; lymphocyte-specific protein tyrosine kinase; OTTHUMP00000008640; OTTHUMP00000008740; OTTHUMP00000008741; p56(LSTRA) protein-tyrosine kinase; p56<lck>; p56lck; p56-LCK; pp58lck; Protein YT16; Proto-oncogene Lck; Proto-oncogene tyrosine-protein kinase LCK; RP4-675E8.4; t cell-specific protein-tyrosine kinase; T-lymphocyte specific protein tyrosine kinase p56lck; tyr; tyrosine-protein kinase Lck; YT16
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3932
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
0.88 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.:
P06239
Gene Symbols:
LCK
Immunogen:
A synthetic phosphorylated peptide around Y505 of human Lck (NP_001036236.1).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-AKT1 (Thr308)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: AKT1
Gene Alias: Akt; Akt kinase; AKT serine/threonine kinase 1; Akt/PKB; akt1; AKT1 kinase; AKT1m; Akt1m protein; Akt1-PA; Akt1-PB; Akt1-PC; Akt1-PD; Akt1-PE; CAKT; C-AKT; CG4006; CG4006-PA; CG4006-PB; CG4006-PC; CG4006-PD; CG4006-PE; CWS6; dAkt; D-Akt; dAkt kinase; dAKT/dPKB; dAkt/PKB; DAKT1; DAKT1/PKB; Dmel\CG4006; Dmel_CG4006; dPKB; DRAC-PK; DRAC-PK66; DRAC-PK85; l(3)04226; l(3)89Bq; murine thymoma viral (v-akt) oncogene homolog 1; pAkt; P-AKT; PKB; PKB alpha; PKB beta; PKB gamma; PKB/AKT; PKB/dAKT; PKBalpha; PKB-ALPHA; PKBG; PRKBA; protein kinase B; Protein kinase B alpha; protein kinase B-alpha; proto-oncogene c-Akt; RAC; rac protein kinase alpha; RAC protein kinase alpha RAC-PK alpha; RAC serine/threonine protein kinase; RAC serine/threonine-protein kinase; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; RacPK; RAC-PK-alpha; RAC-PK-beta; RAC-PK-gamma; related to A and C kinases; related to PKA to PKC protein kinases; related to the A and C kinases; SD10374p; serine/threonine protein kinase
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11651
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.36 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.: P31750
Gene Symbols: AKT1
Immunogen: A synthetic phosphorylated peptide around T308 of human AKT1 (NP_005154.2).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-AKT1 (Thr308)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
AKT1
Gene Alias:
Akt; Akt kinase; AKT serine/threonine kinase 1; Akt/PKB; akt1; AKT1 kinase; AKT1m; Akt1m protein; Akt1-PA; Akt1-PB; Akt1-PC; Akt1-PD; Akt1-PE; CAKT; C-AKT; CG4006; CG4006-PA; CG4006-PB; CG4006-PC; CG4006-PD; CG4006-PE; CWS6; dAkt; D-Akt; dAkt kinase; dAKT/dPKB; dAkt/PKB; DAKT1; DAKT1/PKB; Dmel\CG4006; Dmel_CG4006; dPKB; DRAC-PK; DRAC-PK66; DRAC-PK85; l(3)04226; l(3)89Bq; murine thymoma viral (v-akt) oncogene homolog 1; pAkt; P-AKT; PKB; PKB alpha; PKB beta; PKB gamma; PKB/AKT; PKB/dAKT; PKBalpha; PKB-ALPHA; PKBG; PRKBA; protein kinase B; Protein kinase B alpha; protein kinase B-alpha; proto-oncogene c-Akt; RAC; rac protein kinase alpha; RAC protein kinase alpha RAC-PK alpha; RAC serine/threonine protein kinase; RAC serine/threonine-protein kinase; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; RacPK; RAC-PK-alpha; RAC-PK-beta; RAC-PK-gamma; related to A and C kinases; related to PKA to PKC protein kinases; related to the A and C kinases; SD10374p; serine/threonine protein kinase
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11651
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.36 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.:
P31750
Gene Symbols:
AKT1
Immunogen:
A synthetic phosphorylated peptide around T308 of human AKT1 (NP_005154.2).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG