PIPA5121307

Phospho-IRF3 (Ser386) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5121307-Each-of-1 In Stock ₹ 43,079.46

PIPA5121307 - Each of 1

₹ 43,079.46

In Stock

Quantity

1

Base Price: ₹ 43,079.46

GST (18%): ₹ 7,754.303

Total Price: ₹ 50,833.763

Antigen

Phospho-IRF3 (Ser386)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IRF3

Gene Alias

C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

292892, 3661, 54131

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.45 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.

P70671, Q14653

Gene Symbols

IRF3

Immunogen

A synthetic phosphorylated peptide around S386 of human IRF3 (NP_001562.1).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA578410

--

Img

Thermo Scientific

PIMA526284

--

Img

Thermo Scientific

PIPA5121144

--

Img

Thermo Scientific

PIPA540650

--

Img

Thermo Scientific

PIPA582512

--

Img

Thermo Scientific

PIPA595686

--

Img

Thermo Scientific

PIPA551406

--

Img

Thermo Scientific

PIMA525670

--

Description

  • Positive test controls include: HeLa, NIH/3T3
  • The target is usually found in the following locations: Cytoplasm, Nucleus
  • Immunogen sequence: ASSLE IFR3 (interferon regulatory factor 3) is a key transcriptional regulator of type I interferon (IFN)-dependent immune responses
  • It plays a critical role in the innate immune response against DNA and RNA viruses
  • IFR3 regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters
  • It acts as a more potent activator of the IFN-beta gene than the IFN-alpha gene and plays a critical role in both the early and late phases of the IFNA/B gene induction
  • IFR3 is found in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA, or toll-like receptor signaling
  • It is phosphorylated by IKBKE and TBK1 kinases
  • This induces a conformational change, leading to its dimerization and nuclear localization and association with CREB binding protein to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of the type I IFN and ISG genes
  • Mutations in the gene can result in encephalopathy, acute, infection-induced, herpes-specific 7.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5121307

--


Antigen:
Phospho-IRF3 (Ser386)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IRF3

Gene Alias:
C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
292892, 3661, 54131

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.45 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.:
P70671, Q14653

Gene Symbols:
IRF3

Immunogen:
A synthetic phosphorylated peptide around S386 of human IRF3 (NP_001562.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5121308

--


Antigen:
Phospho-MYL9 (Ser19)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MYL9

Gene Alias:
20 kDa myosin light chain; AI327049; DTNB; G1; Isoform L20-A; LC20; light polypeptide 9; MGC3505; MLC2; MLC-2; MLC20; MLC-2C; MRLC1; myl9; myl9.L; myl9b; myl9l; Mylc2c; myosin light chain 2; myosin light chain 9; myosin light chain 9 L homeolog; myosin light chain, regulatory C; myosin regulatory light chain; myosin regulatory light chain 1; myosin regulatory light chain 2, smooth muscle isoform; Myosin regulatory light chain 2, smooth muscle major isoform; myosin regulatory light chain 9; Myosin regulatory light chain MRLC1; myosin regulatory light polypeptide 9; myosin regulatory light polypeptide 9b; myosin RLC; myosin, light chain 9, regulatory; myosin, light chain 9b, regulatory; myosin, light polypeptide 9, regulatory; Myrl2; RLC-C; smooth muscle major isoform; unnamed protein product; XELAEV_18003093mg; zgc:77916

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10398, 296313, 98932

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.37 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P24844, Q64122, Q9CQ19

Gene Symbols:
MYL9

Immunogen:
A synthetic phosphorylated peptide around S19 of human MYL9 (NP_006088.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5121310

--


Antigen:
Phospho-GYS1 (Ser641)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Gys1

Gene Alias:
EC 2.4.1.11; glycogen [starch] synthase, muscle; glycogen synthase; glycogen synthase 1; glycogen synthase 1 (muscle); glycogen synthase 1, muscle; glycogen synthase 3, brain; GSY; GYS; GYS1; Gys3; MGS

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14936, 2997, 690987

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.28 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
A2RRU1, P13807, Q9Z1E4

Gene Symbols:
Gys1

Immunogen:
A synthetic phosphorylated peptide around S641 of human Glycogen synthase 1 (GYS1) (NP_0020942)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5121312

--


Antigen:
Phospho-STAT5A/B (Tyr694)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STAT5B

Gene Alias:
AA959963; Mammary gland factor; mammary gland factor STAT5A; mammary gland factor STAT5B; mammary gland factor; transcription factor; MGF; Mpf; signal transducer and activator of transcription 5; Signal transducer and activator of transcription 5a; Signal transducer and activator of transcription 5B; STA5B; STAT; STAT5; Stat5a; Stat5b; transcription factor STAT5B

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20850, 20851, 24918, 25126, 6776, 6777

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
2.38 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3

Gene Accession No.:
P42229, P42230, P42232, P51692, P52632, Q62771

Gene Symbols:
STAT5A, STAT5B

Immunogen:
A synthetic phosphorylated peptide around Y694 of human STAT5 (NP_003143.2/NP_036580.2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG