Home Products Antibodies Primary Antibodies PIPA5121314
PIPA5121314

Phosphoserine/threonine Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5121314-Each-of-1 In Stock ₹ 43,079.46

PIPA5121314 - Each of 1

₹ 43,079.46

In Stock

Quantity

1

Base Price: ₹ 43,079.46

GST (18%): ₹ 7,754.303

Total Price: ₹ 50,833.763

Antigen

Phosphoserine/threonine

Classification

Polyclonal

Conjugate

Unconjugated

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Target Species

Chemical, Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Concentration

4.17 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3

Immunogen

A synthetic peptide corresponding to a sequence containing phosphorylated S & T

Quantity

100 μL

Primary or Secondary

Primary

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Target Molecule

Chemical

Description

  • Positive test controls include: C6
  • A hallmark of signal transduction pathways is the reversible phosphorylation of serine and threonine residues within specific sequences, or motifs, in target proteins
  • Specific signaling motifs include not only sequences that are recognized by protein kinases, but also those that are recognized by phosphorylation-dependent binding proteins like 14-3-3
  • These modular phosphoprotein interacting domains are critical elements in modulating, directing and amplifying intracellular communications
  • Many critical protein kinases can be regulated by phosphorylation at a specific serine or threonine surrounded by phenylalanine or tyrosine
  • For example, Akt, an important kinase that regulates cell survival, is activated by phosphorylation at Ser473, a site surrounded by phenylalanine and tyrosine
  • RSK1, p70 S6 K, and certain PKC isoforms also contain a similar consensus phosphorylation site
  • Phosphorylation of these sites is required for kinase activity
  • The (Ser/Thr) Phe Antibody is a powerful tool for discovery of new proteins containing this important regulatory motif.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5121314

--

Antigen:
Phosphoserine/threonine
Classification:
Polyclonal
Conjugate:
Unconjugated
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Target Species:
Chemical, Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Concentration:
4.17 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Immunogen:
A synthetic peptide corresponding to a sequence containing phosphorylated S & T
Quantity:
100 μL
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Target Molecule:
Chemical

Img

Thermo Scientific

PIPA5121315

--

Antigen:
Phospho-Histone H4 (Ser1)
Classification:
Polyclonal
Conjugate:
Unconjugated
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Concentration:
0.63 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Immunogen:
A synthetic phosphorylated peptide around S1 of human Histone H4 (NP_003529.1).
Quantity:
100 μL
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Target Molecule:
__

Img

Thermo Scientific

PIPA5121316

--

Antigen:
Phosphotyrosine
Classification:
Polyclonal
Conjugate:
Unconjugated
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Target Species:
Chemical, Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.3 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Immunogen:
A synthetic peptide corresponding to a sequence containing phosphorylated S & T.
Quantity:
100 μL
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Target Molecule:
Chemical

Img

Thermo Scientific

PIPA5121317

--

Antigen:
Phospho-IRE1 alpha (Ser551)
Classification:
Polyclonal
Conjugate:
Unconjugated
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Concentration:
0.44 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Immunogen:
A synthetic phosphorylated peptide around S551 of human ERN1 (NP_0014243)
Quantity:
100 μL
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Target Molecule:
__