PIPA5121418
Histone H2A.X Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5121418-Each-of-1 | In Stock | ₹ 43,079.46 |
PIPA5121418 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,079.46
GST (18%): ₹ 7,754.303
Total Price: ₹ 50,833.763
Antigen
Histone H2A.X
Classification
Polyclonal
Conjugate
Unconjugated
Gene
H2AX
Gene Alias
AW228881; gamma H2AX; gammaH2ax; H2A histone family member X; H2A histone family, member X; H2A.X; H2A.X variant histone; H2A/X; h2afx; H2ax; H2AX histone; Hist5-2ax; histone 5 protein 2ax; histone H2A.x; Histone H2a/x; Histone H2AX; RGD1566119; similar to H2A histone family, member X; zgc:56329
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3014
Content And Storage
-20°C or -80°C if preferred
Form
Liquid
Applications
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin)
Concentration
0.04 mg/mL
Formulation
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.
P16104
Gene Symbols
H2AX
Immunogen
Synthesized peptide derived from Human Histone H2AX protein (130-142aa)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody tested in Indirect ELISA Histone H2A.X (H2AX) is a member of the histone H2A family which is one of the four core histones making up the nucleosome core particle
- In eukaryotes, DNA double strand breaks (DSBs) have been shown to trigger the phosphorylation of serine 139 at the carboxy terminus of histone H2AX resulting in gamma-H2AX
- The phosphorylation of H2AX can be detected by Western blotting or immunofluorescence, revealing the frequency of DSBs
- The phosphatidylinositol 3-kinases have been implicated in H2AX phosphorylation, but it is unclear if ATM is the primary H2AX kinase or if other members of the family such as DNA-PK and ATR contribute in a similar manner
- Structurally, H2A.x contains 143 amino acid residues
- Histone H2A.X is considered a basal histone, being synthesized in G1 as well as in S-phase, and its mRNA contains polyA addition motifs and a polyA tail along with the conserved stem-loop and U7 binding sequences involved in the processing and stability of replication type histone mRNAs
- There are two forms of Histone H2A.X mRNA, one about 1600 bases long and contains polyA; the other about 575 bases long, lacking polyA
- The short form behaves as a replication type histone mRNA, while the longer behaves as a basal type histone mRNA
- Histone H2A.X maps to the 11q23.2-q23.3 region of the human chromosome
- Histone H2A.x contributes to histone-formation and therefore the structure of DNA
- Histone H2A variant H2A.x specifically regulates the interaction of MDC1 (mediator of DNA damage checkpoint protein 1), a DNA repair protein to the sites of DNA damage.
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Antigen: Histone H2A.X
Classification: Polyclonal
Conjugate: Unconjugated
Gene: H2AX
Gene Alias: AW228881; gamma H2AX; gammaH2ax; H2A histone family member X; H2A histone family, member X; H2A.X; H2A.X variant histone; H2A/X; h2afx; H2ax; H2AX histone; Hist5-2ax; histone 5 protein 2ax; histone H2A.x; Histone H2a/x; Histone H2AX; RGD1566119; similar to H2A histone family, member X; zgc:56329
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3014
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin)
Concentration: 0.04 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.: P16104
Gene Symbols: H2AX
Immunogen: Synthesized peptide derived from Human Histone H2AX protein (130-142aa)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Histone H2A.X
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
H2AX
Gene Alias:
AW228881; gamma H2AX; gammaH2ax; H2A histone family member X; H2A histone family, member X; H2A.X; H2A.X variant histone; H2A/X; h2afx; H2ax; H2AX histone; Hist5-2ax; histone 5 protein 2ax; histone H2A.x; Histone H2a/x; Histone H2AX; RGD1566119; similar to H2A histone family, member X; zgc:56329
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3014
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin)
Concentration:
0.04 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.:
P16104
Gene Symbols:
H2AX
Immunogen:
Synthesized peptide derived from Human Histone H2AX protein (130-142aa)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: HS3ST3B1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HS3ST3B1
Gene Alias: 30ST3B1; 3-OST-3B; 3OST3B1; h3-OST-3B; heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1; heparan sulfate 3-O-sulfotransferase 3B1; heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1; Heparan sulfate glucosamine 3-O-sulfotransferase 3B1; heparan sulfate-glucosamine 3-sulfotransferase 3B1; HS3ST3B; HS3ST3B1; LOC100724084
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 9953
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin)
Concentration: 2.89 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.: Q9Y662
Gene Symbols: HS3ST3B1
Immunogen: Recombinant Human Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 protein (54-390aa)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
HS3ST3B1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HS3ST3B1
Gene Alias:
30ST3B1; 3-OST-3B; 3OST3B1; h3-OST-3B; heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1; heparan sulfate 3-O-sulfotransferase 3B1; heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1; Heparan sulfate glucosamine 3-O-sulfotransferase 3B1; heparan sulfate-glucosamine 3-sulfotransferase 3B1; HS3ST3B; HS3ST3B1; LOC100724084
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
9953
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin)
Concentration:
2.89 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.:
Q9Y662
Gene Symbols:
HS3ST3B1
Immunogen:
Recombinant Human Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 protein (54-390aa)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: IGSF3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IGSF3
Gene Alias: 1700016K10Rik; 2810035F16Rik; 4833439O17Rik; EWI3; EWI-3; Glu-Trp-Ile EWI motif-containing protein 3; Igsf3; immunoglobin superfamily, member 3; immunoglobulin superfamily member 3; immunoglobulin superfamily, member 3; Kiaa0466; LCDD; mKIAA0466; RP4-781D12.1; V8
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 3321
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Western Blot
Concentration: 3 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.: O75054
Gene Symbols: IGSF3
Immunogen: Recombinant Human Immunoglobulin superfamily member 3 protein (111-399aa)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
IGSF3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IGSF3
Gene Alias:
1700016K10Rik; 2810035F16Rik; 4833439O17Rik; EWI3; EWI-3; Glu-Trp-Ile EWI motif-containing protein 3; Igsf3; immunoglobin superfamily, member 3; immunoglobulin superfamily member 3; immunoglobulin superfamily, member 3; Kiaa0466; LCDD; mKIAA0466; RP4-781D12.1; V8
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
3321
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Western Blot
Concentration:
3 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.:
O75054
Gene Symbols:
IGSF3
Immunogen:
Recombinant Human Immunoglobulin superfamily member 3 protein (111-399aa)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: KBTBD7
Classification: Polyclonal
Conjugate: Unconjugated
Gene: KBTBD7
Gene Alias: KBTBD7; kelch repeat and BTB (POZ) domain containing 7; kelch repeat and BTB domain containing 7; kelch repeat and BTB domain-containing protein 7; kelch repeat and BTB domain-containing protein 7-like
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 84078
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration: 3.08 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.: Q8WVZ9
Gene Symbols: KBTBD7
Immunogen: Recombinant Human Kelch repeat and BTB domain-containing protein 7 protein (475-684aa)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
KBTBD7
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
KBTBD7
Gene Alias:
KBTBD7; kelch repeat and BTB (POZ) domain containing 7; kelch repeat and BTB domain containing 7; kelch repeat and BTB domain-containing protein 7; kelch repeat and BTB domain-containing protein 7-like
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
84078
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration:
3.08 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.:
Q8WVZ9
Gene Symbols:
KBTBD7
Immunogen:
Recombinant Human Kelch repeat and BTB domain-containing protein 7 protein (475-684aa)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG