PIPA5121441

NHLRC1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5121441-Each-of-1 In Stock ₹ 43,079.46

PIPA5121441 - Each of 1

₹ 43,079.46

In Stock

Quantity

1

Base Price: ₹ 43,079.46

GST (18%): ₹ 7,754.303

Total Price: ₹ 50,833.763

Antigen

NHLRC1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NHLRC1

Gene Alias

AI505271; B230309E09Rik; bA204B7.2; E3 ubiquitin-protein ligase NHLRC1; EPM2A; EPM2B; Malin; NHL repeat containing 1; NHL repeat containing E3 ubiquitin protein ligase 1; NHL repeat-containing protein 1; NHLRC1; RING-type E3 ubiquitin transferase NHLRC1

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

378884

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin)

Concentration

3.63 mg/mL

Formulation

PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.

Q6VVB1

Gene Symbols

NHLRC1

Immunogen

Recombinant Human E3 ubiquitin-protein ligase NHLRC1 protein (86-395aa)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody tested in Indirect ELISA Progressive myoclonic epilepsy type 2 (EPM2), also called Lafora disease, is an autosomal recessive disease characterized by grand mal seizures and/or myoclonus at about 15 years of age
  • Rapid and severe mental deterioration follows, often with psychotic features
  • Survival is less than 10 years after onset
  • Starch-like, endoplasmic reticulum-associated polyglucosans, called Lafora bodies, can be observed in brain, muscle, liver and heart
  • One cause of Lafora disease is due to mutations in NHLRC1, the gene encoding Malin
  • Forty-nine different mutations in NHLRC1 have been shown to cause EPM2
  • Malin, also called NHL repeat-containing protein 1, is a single subunit E3 ubiquitin ligase, containing 6 NHL repeats and 1 RING-type zinc finger
  • Malin's RING domain is responsible for its ability to mediate ubiquitination
  • Malin interacts with and polyubiquitinates Laforin, a protein also implicated in EPM2
  • Malin localizes to the endoplasmic reticulum and, to a lesser extent, in the nucleus
  • Malin is expressed in brain, cerebellum, spinal cord, medulla, heart, liver, skeletal muscle and pancreas.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5121441

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Antigen:
NHLRC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NHLRC1

Gene Alias:
AI505271; B230309E09Rik; bA204B7.2; E3 ubiquitin-protein ligase NHLRC1; EPM2A; EPM2B; Malin; NHL repeat containing 1; NHL repeat containing E3 ubiquitin protein ligase 1; NHL repeat-containing protein 1; NHLRC1; RING-type E3 ubiquitin transferase NHLRC1

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
378884

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin)

Concentration:
3.63 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
Q6VVB1

Gene Symbols:
NHLRC1

Immunogen:
Recombinant Human E3 ubiquitin-protein ligase NHLRC1 protein (86-395aa)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5121442

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Antigen:
ompF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
__

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
4.13 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Recombinant Escherichia coli Outer membrane protein F protein (23-362aa)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bacteria

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5121444

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Antigen:
OR5H6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
OR5H6

Gene Alias:
Olfactory receptor 5H6; olfactory receptor family 5 subfamily H member 6 (gene/pseudogene); olfactory receptor OR3-11; olfactory receptor, family 5, subfamily H, member 6; OR3-11; OR5H6

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
79295

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunocytochemistry

Concentration:
3.71 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
Q8NGV6

Gene Symbols:
OR5H6

Immunogen:
Recombinant Human Olfactory receptor 5H6 protein (277-292aa)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA5121446

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Antigen:
Osteocrin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
OSTN

Gene Alias:
MUSCLIN; Ostc; osteocrin; Ostn; Processed Osteocrin

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
344901

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin)

Concentration:
2.63 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
P61366

Gene Symbols:
OSTN

Immunogen:
Recombinant Human Osteocrin protein (28-133aa)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG