PIPA5121814

JAK2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5121814-Each-of-1 In Stock ₹ 16,675.64

PIPA5121814 - Each of 1

₹ 16,675.64

In Stock

Quantity

1

Base Price: ₹ 16,675.64

GST (18%): ₹ 3,001.615

Total Price: ₹ 19,677.255

Antigen

JAK2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

JAK2

Gene Alias

EC 2.7.10.2; Fd17; JAK 2; JAK2; JAK-2; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); JTK 10; JTK10; kinase Jak2; THCYT3; Tyrosine-protein kinase JAK2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3717

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.

O60674

Gene Symbols

JAK2

Immunogen

Recombinant protein Janus Kinase 2. The antigen corresponds to amino acid range 508-800 of the target protein.

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Janus kinase 2 (JAK2) is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways and is mutated in polycythemia vera
  • This kinase contains the catalytic domain (JH1) of JAK2
  • The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
  • Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
  • JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
  • Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex
  • Mutations affecting JAK2 can cause Budd-Chiari syndrome, Polycythemia vera, Thrombocythemia 3, myelofibrosis, or Acute myelogenous leukemia.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5121814

--


Antigen:
JAK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
JAK2

Gene Alias:
EC 2.7.10.2; Fd17; JAK 2; JAK2; JAK-2; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); JTK 10; JTK10; kinase Jak2; THCYT3; Tyrosine-protein kinase JAK2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3717

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
O60674

Gene Symbols:
JAK2

Immunogen:
Recombinant protein Janus Kinase 2. The antigen corresponds to amino acid range 508-800 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA5121815

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Antigen:
ITIH5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ITIH5

Gene Alias:
4631408O11Rik; 5430408M01Rik; DKFZp686F0145; E130106B02; inter-alpha (globulin) inhibitor H5; inter-alpha trypsin inhibitor heavy chain precursor 5; inter-alpha-inhibitor heavy chain 5; inter-alpha-trypsin inhibitor heavy chain 5; inter-alpha-trypsin inhibitor heavy chain family member 5; inter-alpha-trypsin inhibitor heavy chain family, member 5; inter-alpha-trypsin inhibitor heavy chain H5; ITI heavy chain H5; ITIH5; ITI-HC5; KIAA1953; MGC10848; PP14776; UNQ311/PRO354

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
209378

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q8BJD1

Gene Symbols:
ITIH5

Immunogen:
Recombinant protein Inter Alpha-Globulin Inhibitor H5. The antigen corresponds to amino acid range 569-737 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5121816

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Antigen:
ITIH3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ITIH3

Gene Alias:
AW108094; H3P; inter-alpha (globulin) inhibitor H3; inter-alpha (globulin) inhibitor, H3 polypeptide; inter-alpha trypsin inhibitor, heavy chain 3; inter-alpha-inhibitor H3 chain; inter-alpha-inhibitor heavy chain 3; inter-alpha-trypsin inhibitor heavy chain 3; inter-alpha-trypsin inhibitor heavy chain H3; Intin3; ITI heavy chain H3; ITIH3; Itih-3; ITI-HC3; PAIHC3; pre-alpha (globulin) inhibitor, H3 polypeptide; pre-alpha-inhibitor heavy chain 3; pre-alpha-inhibitor, heavy chain 3; serum-derived hyaluronan-associated protein; SHAP

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3699

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.52 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q06033

Gene Symbols:
ITIH3

Immunogen:
Recombinant protein Inter Alpha-Globulin Inhibitor H3. The antigen corresponds to amino acid range 279-467 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA5121819

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Antigen:
ITFG1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Itfg1

Gene Alias:
2310047C21Rik; AI314457; CDA08; CDA08-like protein; D8Wsu49e; hypothetical protein CDA08; integrin alpha FG-GAP repeat containing 1; integrin-alpha FG-GAP repeat-containing protein 1; ITFG1; Linkin; LNKN-1; Protein TIP; T-cell immunomodulatory protein; TIP

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
81533

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q8TB96

Gene Symbols:
Itfg1

Immunogen:
Recombinant protein Integrin Alpha FG GAP Repeat Containing Protein 1. The antigen corresponds to amino acid range 55-306 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG