PIPA5121824

IL31RA Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5121824-Each-of-1 In Stock ₹ 16,675.64

PIPA5121824 - Each of 1

₹ 16,675.64

In Stock

Quantity

1

Base Price: ₹ 16,675.64

GST (18%): ₹ 3,001.615

Total Price: ₹ 19,677.255

Antigen

IL31RA

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IL31RA

Gene Alias

class I cytokine receptor; CRL; CRL 3; CRL3; CRL3Glmr; cytokine receptor NR10; cytokine receptor-like 3; GLM R; Glmr; GLM-R; GLM-RMGC125346; GP130 like receptor; gp130-like monocyte receptor; Gp130-like receptor; GPL; HGLM R; HGLMR; hGLM-R; IL 31RA; IL-31 receptor subunit alpha; IL31R subunit alpha; IL-31R subunit alpha; Il31ra; IL-31RA; IL-31RAGPLCRL; IL-31R-alpha; interleukin 31 receptor A; interleukin 31RA; interleukin-31 receptor subunit alpha; MGC125346; mGLM-R; novel cytokine receptor 10; NR10; PLCA 2; PLCA2; PRO21384; soluble type I cytokine receptor CRL3; UNQ6368/PRO21073/PRO21384; ZcytoR17

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

133396

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.

Q8NI17

Gene Symbols

IL31RA

Immunogen

Recombinant protein Interleukin 31 Receptor A. The antigen corresponds to amino acid range 205-456 of the target protein.

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • IL-31 is a T cell cytokine that is preferentially produced by T helper type 2 cells
  • IL-31 signals through a heterodimeric receptor composed of the IL-31 receptor (IL-31R) and the oncostatin M receptor (OSM)
  • This receptor complex recruits JAK1, JAK2, Stat1, Stat3 and Stat5 signaling pathways, as well as the PI3 kinase/AKT cascade
  • SHP-2 and Shc adapter molecules are also recruited and contribute to an increased activation of the MAP kinase pathway in response to IL-31
  • Overexpression of IL-31 in mice results in pruritus and skin dermatitis resembling human atopic dermatitis (AD)
  • Comparisons between skin from patients with AD and healthy skin showed IL-31R expression at higher levels on epidermal keratinocytes in AD samples
  • Infiltrating cells, more numerous in skin from patients with AD compared with that of healthy individuals, expressed IL-31 mRNA
  • IL-31 may participate in the cause of itch sensation and promote scratching behavior in NC/Nga mice with atopic dermatitis, and may represent a novel target for antipruritic drug development.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5121824

--


Antigen:
IL31RA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL31RA

Gene Alias:
class I cytokine receptor; CRL; CRL 3; CRL3; CRL3Glmr; cytokine receptor NR10; cytokine receptor-like 3; GLM R; Glmr; GLM-R; GLM-RMGC125346; GP130 like receptor; gp130-like monocyte receptor; Gp130-like receptor; GPL; HGLM R; HGLMR; hGLM-R; IL 31RA; IL-31 receptor subunit alpha; IL31R subunit alpha; IL-31R subunit alpha; Il31ra; IL-31RA; IL-31RAGPLCRL; IL-31R-alpha; interleukin 31 receptor A; interleukin 31RA; interleukin-31 receptor subunit alpha; MGC125346; mGLM-R; novel cytokine receptor 10; NR10; PLCA 2; PLCA2; PRO21384; soluble type I cytokine receptor CRL3; UNQ6368/PRO21073/PRO21384; ZcytoR17

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
133396

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q8NI17

Gene Symbols:
IL31RA

Immunogen:
Recombinant protein Interleukin 31 Receptor A. The antigen corresponds to amino acid range 205-456 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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Fischer Scientific

PIPA5121825

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Antigen:
IL20RB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Il20rb

Gene Alias:
AV228068; DIRS1; Fibronectin type III domain containing 6; FNDC6; Gm186; IL-20 receptor subunit beta; IL20R2; IL-20R2; IL20RB; IL-20RB; IL-20R-beta; interleukin 20 receptor beta; interleukin 20 receptor beta subunit; interleukin 20 receptor subunit beta; interleukin-20 receptor II; interleukin-20 receptor subunit beta; RGD1566151; UNQ557/PRO1114

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
53833

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q6UXL0

Gene Symbols:
Il20rb

Immunogen:
Ala37-Glu290 (Accession Q6UXL0), with N-terminal His Tag

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5121826

--


Antigen:
IL20RB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Il20rb

Gene Alias:
AV228068; DIRS1; Fibronectin type III domain containing 6; FNDC6; Gm186; IL-20 receptor subunit beta; IL20R2; IL-20R2; IL20RB; IL-20RB; IL-20R-beta; interleukin 20 receptor beta; interleukin 20 receptor beta subunit; interleukin 20 receptor subunit beta; interleukin-20 receptor II; interleukin-20 receptor subunit beta; RGD1566151; UNQ557/PRO1114

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
53833

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q6UXL0

Gene Symbols:
Il20rb

Immunogen:
Ala37-Glu290 (Accession Q6UXL0), with N-terminal His Tag

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5121828

--


Antigen:
IL17RC

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL17RC

Gene Alias:
1110025H02Rik; CANDF9; Gm19850; IL-17 receptor C; IL17F receptor; IL17RC; IL-17RC; IL17-RC; IL17Rhom; Il17rl; IL-17RL; IL17-RL; interleukin 17 receptor C; interleukin-17 receptor C; Interleukin-17 receptor homolog; interleukin-17 receptor-like protein; UNQ6118/PRO20040/PRO38901; ZcytoR14

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
84818

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q8NAC3

Gene Symbols:
IL17RC

Immunogen:
Recombinant protein Interleukin 17 Receptor C. The antigen corresponds to amino acid range 257-477 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG