PIPA5122071
COX2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5122071-Each-of-1 | In Stock | ₹ 14,185.85 |
PIPA5122071 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 14,185.85
GST (18%): ₹ 2,553.453
Total Price: ₹ 16,739.303
Antigen
COX2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PTGS2
Gene Alias
COII; COX2; Cox-2; COXII; cyclooxygenase; cyclooxygenase 2; cyclooxygenase 2b; cyclooxygenase-2; Cytochrome c oxidase polypeptide II; Cytochrome c oxidase subunit 2; cytochrome c oxidase subunit II; glucocorticoid-regulated inflammatory cyclooxygenase; Gripghs; hCox-2; Macrophage activation-associated marker protein P71/73; mitochondrially encoded cytochrome c oxidase II; MTCO2; MT-CO2; PES-2; PGG/HS; PGH synthase 2; Pghs2; PGHS-2; Pghs-b; PHS II; PHS-2; prostaglandin G/H synthase 2; Prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); Ptgs2; Tis10; TIS10 protein
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5743
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
500 μg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.
P35354
Gene Symbols
PTGS2
Immunogen
Recombinant protein Cyclooxygenase-2. The antigen corresponds to amino acid range 187-425 of the target protein.
Quantity
20 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- COX2 converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis, including production of inflammatory prostaglandins
- The conversion of arachidonate to prostaglandin H2 is a 2 step reaction: a cyclooxygenase (COX) reaction which converts arachidonate to prostaglandin G2 (PGG2) and a peroxidase reaction in which PGG2 is reduced to prostaglandin H2 (PGH2)
- It is constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and is up-regulated under pathological conditions, such as in cancer and inflammation (in contrast to the iso-enzyme PTGS1, which is expressed ubiquitously)
- Up-regulation of COX2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis
- In cancer cells, COX2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis
- COX2 is naturally inhibited by calcitriol (the active form of Vitamin D)
- Glucocorticoids chronically trans-repress PTGS2 gene activity in vivo in part by interfering with transcription initiation and elongation
- COX2 is a target of NSAID such as aspirin, which can reduce pain and swelling from inflammation driven by COX2.
Compare Similar Items
Show Difference
Antigen: COX2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PTGS2
Gene Alias: COII; COX2; Cox-2; COXII; cyclooxygenase; cyclooxygenase 2; cyclooxygenase 2b; cyclooxygenase-2; Cytochrome c oxidase polypeptide II; Cytochrome c oxidase subunit 2; cytochrome c oxidase subunit II; glucocorticoid-regulated inflammatory cyclooxygenase; Gripghs; hCox-2; Macrophage activation-associated marker protein P71/73; mitochondrially encoded cytochrome c oxidase II; MTCO2; MT-CO2; PES-2; PGG/HS; PGH synthase 2; Pghs2; PGHS-2; Pghs-b; PHS II; PHS-2; prostaglandin G/H synthase 2; Prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); Ptgs2; Tis10; TIS10 protein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5743
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.: P35354
Gene Symbols: PTGS2
Immunogen: Recombinant protein Cyclooxygenase-2. The antigen corresponds to amino acid range 187-425 of the target protein.
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
COX2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PTGS2
Gene Alias:
COII; COX2; Cox-2; COXII; cyclooxygenase; cyclooxygenase 2; cyclooxygenase 2b; cyclooxygenase-2; Cytochrome c oxidase polypeptide II; Cytochrome c oxidase subunit 2; cytochrome c oxidase subunit II; glucocorticoid-regulated inflammatory cyclooxygenase; Gripghs; hCox-2; Macrophage activation-associated marker protein P71/73; mitochondrially encoded cytochrome c oxidase II; MTCO2; MT-CO2; PES-2; PGG/HS; PGH synthase 2; Pghs2; PGHS-2; Pghs-b; PHS II; PHS-2; prostaglandin G/H synthase 2; Prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); Ptgs2; Tis10; TIS10 protein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5743
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.:
P35354
Gene Symbols:
PTGS2
Immunogen:
Recombinant protein Cyclooxygenase-2. The antigen corresponds to amino acid range 187-425 of the target protein.
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: COTL1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Cotl1
Gene Alias: 1810074P22Rik; 2010004C08Rik; CLP; coactosin like F-actin binding protein 1; coactosin-like 1; coactosin-like 1 (Dictyostelium); coactosin-like F-actin binding protein 1; coactosin-like protein; coactosin-like protein {ECO:0000250; Cotl1; cotl1 {ECO:0000312; EMBL:AAI58747.1, ECO:0000312; FLJ43657; MGC137989 protein; MGC19733; RGD:1305498}; UniProtKB:Q14019}; Unknown (protein for MGC:63983); wu:fb08h08; zgc:63983
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23406
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.: Q14019
Gene Symbols: Cotl1
Immunogen: Recombinant protein Coactosin Like Protein 1. The antigen corresponds to amino acid range 1-142 of the target protein.
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
COTL1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Cotl1
Gene Alias:
1810074P22Rik; 2010004C08Rik; CLP; coactosin like F-actin binding protein 1; coactosin-like 1; coactosin-like 1 (Dictyostelium); coactosin-like F-actin binding protein 1; coactosin-like protein; coactosin-like protein {ECO:0000250; Cotl1; cotl1 {ECO:0000312; EMBL:AAI58747.1, ECO:0000312; FLJ43657; MGC137989 protein; MGC19733; RGD:1305498}; UniProtKB:Q14019}; Unknown (protein for MGC:63983); wu:fb08h08; zgc:63983
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23406
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.:
Q14019
Gene Symbols:
Cotl1
Immunogen:
Recombinant protein Coactosin Like Protein 1. The antigen corresponds to amino acid range 1-142 of the target protein.
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: COMT
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Comt
Gene Alias: Catechol O-methyltransferase; catecholamine-O-methyltransferase; catechol-O-methyltransferase; catechol-O-methyltransferase 1; catechol-O-methyltransferase isoform; Comt; Comt1; D16Wsu103e; D330014B15Rik; epididymis secretory sperm binding protein Li 98n; HEL-S-98n; OTTHUMP00000197749; OTTHUMP00000197750; testicular tissue protein Li 42
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1312
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.: P21964
Gene Symbols: Comt
Immunogen: Recombinant protein Catechol-O-Methyltransferase. The antigen corresponds to amino acid range 52-271 of the target protein.
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
COMT
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Comt
Gene Alias:
Catechol O-methyltransferase; catecholamine-O-methyltransferase; catechol-O-methyltransferase; catechol-O-methyltransferase 1; catechol-O-methyltransferase isoform; Comt; Comt1; D16Wsu103e; D330014B15Rik; epididymis secretory sperm binding protein Li 98n; HEL-S-98n; OTTHUMP00000197749; OTTHUMP00000197750; testicular tissue protein Li 42
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1312
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.:
P21964
Gene Symbols:
Comt
Immunogen:
Recombinant protein Catechol-O-Methyltransferase. The antigen corresponds to amino acid range 52-271 of the target protein.
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: NDUFS1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NDUFS1
Gene Alias: 5830412M15Rik; 9930026A05Rik; CI-75k; CI-75kD; complex I 75kDa subunit; complex I, mitochondrial respiratory chain, 75-kD subunit; complex I-75kD; MGC26839; mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit; NADH dehydrogenase (ubiquinone) Fe-S protein 1; NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa; NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase); NADH:ubiquinone oxidoreductase core subunit S1; NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; NDUFS1; NDUFS-1; OTTHUMP00000206345; PRO1304
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4719
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.: P28331
Gene Symbols: NDUFS1
Immunogen: Recombinant protein NADH Dehydrogenase Ubiquinone Fe-S Protein 1. The antigen corresponds to amino acid range 524-727 of the target protein.
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NDUFS1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NDUFS1
Gene Alias:
5830412M15Rik; 9930026A05Rik; CI-75k; CI-75kD; complex I 75kDa subunit; complex I, mitochondrial respiratory chain, 75-kD subunit; complex I-75kD; MGC26839; mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit; NADH dehydrogenase (ubiquinone) Fe-S protein 1; NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa; NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase); NADH:ubiquinone oxidoreductase core subunit S1; NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; NDUFS1; NDUFS-1; OTTHUMP00000206345; PRO1304
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4719
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.:
P28331
Gene Symbols:
NDUFS1
Immunogen:
Recombinant protein NADH Dehydrogenase Ubiquinone Fe-S Protein 1. The antigen corresponds to amino acid range 524-727 of the target protein.
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG