PIPA5122152

CBF beta Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5122152-Each-of-1 In Stock ₹ 16,675.64

PIPA5122152 - Each of 1

₹ 16,675.64

In Stock

Quantity

1

Base Price: ₹ 16,675.64

GST (18%): ₹ 3,001.615

Total Price: ₹ 19,677.255

Antigen

CBF beta

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CBFB

Gene Alias

AI893578; CBFB; CBF-beta; core binding factor beta; core-binding factor subunit beta; core-binding factor, beta subunit; PEA2; PEA2-beta; Pebp2; PEBP2B; PEBP2-beta; Pebpb2; polyomavirus enhancer binding protein 2, beta subunit; polyomavirus enhancer-binding protein 2 beta subunit; SL3/AKV core-binding factor beta subunit; SL3-3 enhancer factor 1 beta subunit; SL3-3 enhancer factor 1 subunit beta

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

865

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.

Q13951

Gene Symbols

CBFB

Immunogen

Recombinant protein Core Binding Factor Beta Subunit. The antigen corresponds to amino acid range 1-182 of the target protein.

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • The protein encoded by this gene is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2)
  • The beta subunit is a non-DNA binding regulatory subunit; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters
  • Alternative splicing generates two mRNA variants, each encoding a distinct carboxyl terminus
  • In some cases, a pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript consisting of the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain 11
  • This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype
  • Two transcript variants encoding different isoforms have been found for this gene.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5122152

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Antigen:
CBF beta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CBFB

Gene Alias:
AI893578; CBFB; CBF-beta; core binding factor beta; core-binding factor subunit beta; core-binding factor, beta subunit; PEA2; PEA2-beta; Pebp2; PEBP2B; PEBP2-beta; Pebpb2; polyomavirus enhancer binding protein 2, beta subunit; polyomavirus enhancer-binding protein 2 beta subunit; SL3/AKV core-binding factor beta subunit; SL3-3 enhancer factor 1 beta subunit; SL3-3 enhancer factor 1 subunit beta

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
865

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q13951

Gene Symbols:
CBFB

Immunogen:
Recombinant protein Core Binding Factor Beta Subunit. The antigen corresponds to amino acid range 1-182 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5122164

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Antigen:
Carboxypeptidase A4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CPA4

Gene Alias:
1110019K20Rik; AV009555; Carboxypeptidase A3; carboxypeptidase A4; CPA3; Cpa4; RGD1563619; UNQ694/PRO1339

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51200

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q9UI42

Gene Symbols:
CPA4

Immunogen:
Lys55-Tyr421 (Accession Q9UI42), with N-terminal His Tag

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5122165

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Antigen:
Carboxypeptidase A4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CPA4

Gene Alias:
1110019K20Rik; AV009555; Carboxypeptidase A3; carboxypeptidase A4; CPA3; Cpa4; RGD1563619; UNQ694/PRO1339

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51200

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q9UI42

Gene Symbols:
CPA4

Immunogen:
Lys55-Tyr421 (Accession Q9UI42), with N-terminal His Tag

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA5122166

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Antigen:
CAPS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CAPS

Gene Alias:
Calcyphosin; calcyphosine; calcyphosine 1; CAPS; CAPS1; thyroid protein p24

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
828

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q13938

Gene Symbols:
CAPS

Immunogen:
Recombinant protein Calcyphosine. The antigen corresponds to amino acid range 1-189 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG