PIPA5122176
cGAS Polyclonal Antibody, Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5122176-Each-of-1 | In Stock | ₹ 42,408.50 |
PIPA5122176 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,408.50
GST (18%): ₹ 7,633.53
Total Price: ₹ 50,042.03
Antigen
cGAS
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CGAS
Gene Alias
C6orf150; h-cGAS; MB21D1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
115004
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.98 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.
Q8N884
Gene Symbols
CGAS
Immunogen
Glu225-Lys407
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- cGAS (Cyclic GMP-AMP synthase) is a nucleotidyltransferase that catalyzes the formation of cyclic GMP-AMP (cGAMP) from ATP and GTP and plays a key role in innate immunity
- Catalysis involves both the formation of 2', 5' phosphodiester linkage at the GpA step and the formation of 3', 5' phosphodiester linkage at the ApG step
- This produces c[G(2',5')pA(3'5')p] responses
- cGAS also binds cytosolic DNA directly, leading to the activation and synthesis of cGAMP
- Then, a second messenger binds to and activates TMEM173/STING thereby triggering type-I interferon production
- cGAS is also involved in innate immune sensorship of infection, detection of DNA from bacteria, response to cellular stress, DNA damage, and regulation of cellular senescence.
Compare Similar Items
Show Difference
Antigen: cGAS
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CGAS
Gene Alias: C6orf150; h-cGAS; MB21D1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 115004
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.98 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.: Q8N884
Gene Symbols: CGAS
Immunogen: Glu225-Lys407
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
cGAS
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CGAS
Gene Alias:
C6orf150; h-cGAS; MB21D1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
115004
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.98 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.:
Q8N884
Gene Symbols:
CGAS
Immunogen:
Glu225-Lys407
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: cGAS
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CGAS
Gene Alias: C6orf150; h-cGAS; MB21D1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 115004
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.98 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.: Q8N884
Gene Symbols: CGAS
Immunogen: Glu225-Lys407
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
cGAS
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CGAS
Gene Alias:
C6orf150; h-cGAS; MB21D1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
115004
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.98 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.:
Q8N884
Gene Symbols:
CGAS
Immunogen:
Glu225-Lys407
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Complement C4b
Classification: Polyclonal
Conjugate: Unconjugated
Gene: C4B
Gene Alias: Acidic complement C4; Basic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3; c4 complement; C4A; C4a anaphylatoxin; C4A13; C4A91; C4B; C4B_2; C4B1; C4B12; C4B2; C4B3; C4B5; C4b-A; C4b-B; C4BD; C4d-A; C4d-B; C4F; CH; Chido form of C4; CO4; Complement C4 beta chain; Complement C4 gamma chain; Complement C4-A; Complement C4-A alpha chain; Complement C4-B; Complement C4-B alpha chain; complement C4B1a; complement C4-B-like; complement component 4B (Chido blood group); complement component 4B (Chido blood group), copy 2; CPAMD2; CPAMD3; DADB-112B14.11; FLJ60561; MGC164979
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100293534, 721
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.: P0C0L5
Gene Symbols: C4B, C4B_2
Immunogen: Recombinant protein Complement C4-B. The antigen corresponds to amino acid range 680-756 of the target protein.
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Complement C4b
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
C4B
Gene Alias:
Acidic complement C4; Basic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3; c4 complement; C4A; C4a anaphylatoxin; C4A13; C4A91; C4B; C4B_2; C4B1; C4B12; C4B2; C4B3; C4B5; C4b-A; C4b-B; C4BD; C4d-A; C4d-B; C4F; CH; Chido form of C4; CO4; Complement C4 beta chain; Complement C4 gamma chain; Complement C4-A; Complement C4-A alpha chain; Complement C4-B; Complement C4-B alpha chain; complement C4B1a; complement C4-B-like; complement component 4B (Chido blood group); complement component 4B (Chido blood group), copy 2; CPAMD2; CPAMD3; DADB-112B14.11; FLJ60561; MGC164979
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100293534, 721
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.:
P0C0L5
Gene Symbols:
C4B, C4B_2
Immunogen:
Recombinant protein Complement C4-B. The antigen corresponds to amino acid range 680-756 of the target protein.
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: C2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: C2
Gene Alias: ARMD14; C2; C3/C5 convertase; classical-complement pathway C3/C5 convertase; CO2; Complement C2; Complement C2a fragment; Complement C2b fragment; complement component 2; complement component 2 (within H-2S); complement component C2; complement factor C2; DADB-122G4.1; I79_016440; MHC complement component C2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 717
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.88 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.: P06681
Gene Symbols: C2
Immunogen: Recombinant protein Complement Component 2. The antigen corresponds to amino acid range 245-451 of the target protein.
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
C2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
C2
Gene Alias:
ARMD14; C2; C3/C5 convertase; classical-complement pathway C3/C5 convertase; CO2; Complement C2; Complement C2a fragment; Complement C2b fragment; complement component 2; complement component 2 (within H-2S); complement component C2; complement factor C2; DADB-122G4.1; I79_016440; MHC complement component C2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
717
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.88 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.:
P06681
Gene Symbols:
C2
Immunogen:
Recombinant protein Complement Component 2. The antigen corresponds to amino acid range 245-451 of the target protein.
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG