PIPA5122215

Bcl-2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5122215-Each-of-1 In Stock ₹ 14,185.85

PIPA5122215 - Each of 1

₹ 14,185.85

In Stock

Quantity

1

Base Price: ₹ 14,185.85

GST (18%): ₹ 2,553.453

Total Price: ₹ 16,739.303

Antigen

Bcl-2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Bcl2

Gene Alias

apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12043

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.

P10417

Gene Symbols

Bcl2

Immunogen

Recombinant protein B-Cell Leukemia/Lymphoma 2. The antigen corresponds to amino acid range 2-208 of the target protein.

Quantity

20 μL

Primary or Secondary

Primary

Target Species

Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • BCL-2 is a key regulator of apoptosis that functions to either inhibit or promote cell death
  • The BCL-2 family members are also characterized by dimerizing to further modulate apoptosis
  • Bag1, for example, has been found to form a heterodimer with BCL-2 resulting in the enhancement of the anti-apoptotic effect of BCL-2
  • Bax and Bak have been shown to play a critical role in cytochrome c release from mitochondria and thus initiate apoptosis
  • Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells
  • Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma
  • In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative
  • Two transcript variants of BCL-2, produced by alternate splicing, differ in their C-terminal ends
  • The overexpression of BCL-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5122215

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Antigen:
Bcl-2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Bcl2

Gene Alias:
apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12043

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
P10417

Gene Symbols:
Bcl2

Immunogen:
Recombinant protein B-Cell Leukemia/Lymphoma 2. The antigen corresponds to amino acid range 2-208 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5122221

--


Antigen:
AUP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AUP1

Gene Alias:
AA589454; ancient ubiquitous protein 1; ancient ubiquitous protein 1 isoform 2; ancient ubiquitous protein 1; LOW QUALITY PROTEIN: ancient ubiquitous protein 1; Aup1; AUP1 lipid droplet regulating VLDL assembly factor; AUP1, lipid droplet regulating VLDL assembly factor; HUBCEP52; LOW QUALITY PROTEIN: ancient ubiquitous protein 1; RPL40

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
550

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q9Y679

Gene Symbols:
AUP1

Immunogen:
Recombinant protein Ancient Ubiquitous Protein 1. The antigen corresponds to amino acid range 201-410 of the target protein.

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

PIPA5122224

--


Antigen:
ASAM

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Clmp

Gene Alias:
9030425E11Rik; ACAM; Adipocyte adhesion molecule; adipocyte-specific adhesion molecule; adipocyte-specific protein 5; Asam; ASP5; AW557819; CAR-like membrane protein; Clmp; Coxsackie- and adenovirus receptor-like membrane protein; CSBM; CSBS; CXADR like membrane protein; CXADR-like membrane protein; FLJ22415; LOW QUALITY PROTEIN: CXADR-like membrane protein; Ol16; UNQ318/PRO363; visceral adipose tissue-specific transmembrane protein OL-16

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
79827

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q9H6B4

Gene Symbols:
Clmp

Immunogen:
Thr19-Ser183

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

PIPA5122225

--


Antigen:
ASAM

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Clmp

Gene Alias:
9030425E11Rik; ACAM; Adipocyte adhesion molecule; adipocyte-specific adhesion molecule; adipocyte-specific protein 5; Asam; ASP5; AW557819; CAR-like membrane protein; Clmp; Coxsackie- and adenovirus receptor-like membrane protein; CSBM; CSBS; CXADR like membrane protein; CXADR-like membrane protein; FLJ22415; LOW QUALITY PROTEIN: CXADR-like membrane protein; Ol16; UNQ318/PRO363; visceral adipose tissue-specific transmembrane protein OL-16

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
79827

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300

Gene Accession No.:
Q9H6B4

Gene Symbols:
Clmp

Immunogen:
Thr19-Ser183

Quantity:
20 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG