PIPA512305

IDO Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA512305-Each-of-1 In Stock ₹ 47,015.22

PIPA512305 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

IDO

Classification

Polyclonal

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P14902

Gene Symbols

Ido1

Immunogen

KLH conjugated synthetic peptide between 374-403 amino acids from the C-terminal region of human INDO

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Gene

Ido1

Gene Alias

EC 1.13.11.52; IDO; IDO1; IDO-1; INDO; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine; indoleamine 2,3-dioxygenase 1; indoleamine 23-dioxygenase; Indoleamine-2; indoleamine-pyrrole 2,3 dioxygenase; indoleamine-pyrrole 2,3-dioxygenase

Host Species

Rabbit

Purification Method

Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status

RUO

Gene ID (Entrez)

3620

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Related Products

Img

Thermo Scientific

PIMA523595

--

Img

Novus Biologicals

NB303100

--

Img

Novus Biologicals

NB295963

--

Img

Novus Biologicals

NB303101

--

Img

Novus Biologicals

NB295965

--

Img

Novus Biologicals

NB295978

--

Img

Novus Biologicals

NB522745

--

Img

Novus Biologicals

NB522716

--

Description

  • IDO1 is an intracellular heme-containing enzyme that catalyzes the oxidative cleavage of the indole ring of several important regulatory molecules like tryptophan, serotonin, and melatonin
  • By doing this, IDO1 initiates the production of biologically active metabolites, commonly referred to as kynurenines
  • IDO1 is widely expressed in a variety of human tissues as well as in macrophages and dendritic cells (DCs)
  • In inflammation, interferons (IFNs) act on specific receptors to trigger IDO1 induction
  • The production of IFN-gamma and induction of IDO1 represent important antimicrobial mechanisms
  • Degradation and depletion of tryptophan by IDO1 inhibits the growth of viruses, bacteria and parasites
  • Furthermore, IDO1 plays a complex and crucial role in immunoregulation during infection, pregnancy, autoimmunity, transplantation, and neoplasia.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA512305

--


Antigen:
IDO

Classification:
Polyclonal

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P14902

Gene Symbols:
Ido1

Immunogen:
KLH conjugated synthetic peptide between 374-403 amino acids from the C-terminal region of human INDO

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Gene:
Ido1

Gene Alias:
EC 1.13.11.52; IDO; IDO1; IDO-1; INDO; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine; indoleamine 2,3-dioxygenase 1; indoleamine 23-dioxygenase; Indoleamine-2; indoleamine-pyrrole 2,3 dioxygenase; indoleamine-pyrrole 2,3-dioxygenase

Host Species:
Rabbit

Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status:
RUO

Gene ID (Entrez):
3620

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIPA512315

--


Antigen:
AKR1B1

Classification:
Polyclonal

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P15121

Gene Symbols:
AKR1B1

Immunogen:
KLH conjugated synthetic peptide between 290-316 amino acids from the C-terminal region of human AKR1B1

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Gene:
AKR1B1

Gene Alias:
ADR; Ahr1; Ahr-1; Akr1b1; Akr1b3; Akr1b4; Aldehyde reductase; aldehyde reductase 1; Aldehyde reductase 1 (low Km aldose reductase) (5.8 kb PstI fragment, probably the functional gene); aldo-keto reductase family 1; aldo-keto reductase family 1 member B; aldo-keto reductase family 1 member B1; aldo-keto reductase family 1 member B1; aldose reductase; Aldo-keto reductase family 1 member B3; aldo-keto reductase family 1, member B1 (aldose reductase); aldo-keto reductase family 1, member B3 (aldose reductase); aldo-keto reductase family 1, member B4 (aldose reductase); Aldor1; Aldose reductase; ALDR1; ALDRED; Alr; Alr2; ALR-P-I; AR; Lii5-2 CTCL tumor antigen; low Km aldose reductase; member B1 (aldose reductase); RATALDRED

Host Species:
Rabbit

Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status:
RUO

Gene ID (Entrez):
231

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIPA512327

--


Antigen:
Sigma-1 Receptor

Classification:
Polyclonal

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
O55242, Q99720

Gene Symbols:
SIGMAR1

Immunogen:
KLH conjugated synthetic peptide between 118-147 amino acids from the central region of human OPRS1

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
SIGMAR1

Gene Alias:
AAG8; Aging-associated gene 8 protein; AL024364; ALS16; DSMA2; hSigmaR1; mSigmaR1; opioid receptor, sigma 1; Oprs1; RP23 167I12.6; SIG 1R; SIG-1R; sigma 1 receptor variant SR-1D; sigma 1-type opioid receptor; Sigma non-opioid intracellular receptor 1; sigma1 receptor; Sigma-1 Receptor; sigma1R; sigma1-receptor; Sigmar1; SR BP; SR31747 binding protein 1; SR31747-binding protein; SRBP; SR-BP; SR-BP1; zgc:56378

Host Species:
Rabbit

Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status:
RUO

Gene ID (Entrez):
10280, 18391

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIPA512329

--


Antigen:
ANGEL2

Classification:
Polyclonal

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q5VTE6

Gene Symbols:
ANGEL2

Immunogen:
KLH conjugated synthetic peptide between 108-138 amino acids from the central region of human ANGEL2

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Conjugate:
Unconjugated

Gene:
ANGEL2

Gene Alias:
2610307I21Rik; 5730410O10Rik; AI845692; angel homolog 2; angel homolog 2 (Drosophila); ANGEL2; Ccr4d; D1Ertd396e; D1Ertd654e; KIAA0759L; MNCb-4273; Protein angel homolog 2; RGD1305056

Host Species:
Rabbit

Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status:
RUO

Gene ID (Entrez):
90806

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid