PIPA512447
NPM1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA512447-Each-of-1 | In Stock | ₹ 46,929.66 |
PIPA512447 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,929.66
GST (18%): ₹ 8,447.339
Total Price: ₹ 55,376.999
Antigen
NPM1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NPM1
Gene Alias
B23; B23 antibody; B23NP; MGC104254; mNPM antibody; mNPM1 antibody; NO38; NO38 antibody; Npm; npm1; npm1.L; Nucleolar phosphoprotein B23; nucleolar protein B23.1; nucleolar protein B23/No38; nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog; nucleophosmin 1; nucleophosmin/nucleoplasmin family, member 1; nucleoplasmin; numatrin; numatrin antibody; testicular tissue protein Li 128; unnamed protein product; XELAEV_18020022mg
Host Species
Rabbit
Purification Method
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status
RUO
Gene ID (Entrez)
4869
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
2 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P06748
Gene Symbols
NPM1
Immunogen
KLH conjugated synthetic peptide between 198-226 amino acids from the C-terminal region of human NPM1
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- NPM1 (Nucleophosmin 1, B23, nutramin, NO38) is a ubiquitously expressed phosphoprotein involved in ribosome assembly/transport, cytoplasmic/nuclear trafficking, regulation of DNA polymerase alpha activity, centrosome duplication, and regulation of p53
- NPM1 continuously shuttles between the nucleus, cytoplasm, nucleolus and chaperoning core histones from the nucleus to the cytoplasm
- NPM1 has been shown to bind nucleic acid, prevent protein aggregation via its chaperon activities, protect enzymes during thermal denaturation, and facilitate renaturation of chemically denatured proteins
- In its cellular structure role, there is evidence suggesting NPM1 is associated with the centrosome, and is the substrate of CDK2/cyclin E during duplication of centrosomes (cellular division)
- Due to the NPM1 gene interaction with several tumor-associated chromosome translocations, NPM1 is thought to be a portion of several fusion proteins: NPM-ALK, NPM-RAR, and NPM-MLF1
- While it is not thought to be part of the transforming potential of these fusion proteins, NPM1 is believed to act as the interface for oligomerization and oncogenic conversion of these tumor promoting fusion proteins
- Further, NPM1 is also known to sequester the tumor suppressor RF in the nucleolus, protecting it from degradation until it is necessary
- Dysfunction of the NPM1 protein is associated with diseases such as acute myeloid leukemia and lymphomatoid papulosis.
Compare Similar Items
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Antigen: NPM1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NPM1
Gene Alias: B23; B23 antibody; B23NP; MGC104254; mNPM antibody; mNPM1 antibody; NO38; NO38 antibody; Npm; npm1; npm1.L; Nucleolar phosphoprotein B23; nucleolar protein B23.1; nucleolar protein B23/No38; nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog; nucleophosmin 1; nucleophosmin/nucleoplasmin family, member 1; nucleoplasmin; numatrin; numatrin antibody; testicular tissue protein Li 128; unnamed protein product; XELAEV_18020022mg
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status: RUO
Gene ID (Entrez): 4869
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 2 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P06748
Gene Symbols: NPM1
Immunogen: KLH conjugated synthetic peptide between 198-226 amino acids from the C-terminal region of human NPM1
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NPM1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NPM1
Gene Alias:
B23; B23 antibody; B23NP; MGC104254; mNPM antibody; mNPM1 antibody; NO38; NO38 antibody; Npm; npm1; npm1.L; Nucleolar phosphoprotein B23; nucleolar protein B23.1; nucleolar protein B23/No38; nucleolar protein NO38; Nucleophosmin; nucleophosmin (nucleolar phosphoprotein B23, numatrin); nucleophosmin (nucleolar phosphoprotein B23, numatrin) L homeolog; nucleophosmin 1; nucleophosmin/nucleoplasmin family, member 1; nucleoplasmin; numatrin; numatrin antibody; testicular tissue protein Li 128; unnamed protein product; XELAEV_18020022mg
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status:
RUO
Gene ID (Entrez):
4869
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
2 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P06748
Gene Symbols:
NPM1
Immunogen:
KLH conjugated synthetic peptide between 198-226 amino acids from the C-terminal region of human NPM1
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PCNA
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Pcna
Gene Alias: ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; hypothetical protein LOC515499; MGC8367; Pcna; pcna protein; Pcna/cyclin; PCNAR; POL30; Proliferating cell nuclear antigen; wu:fa28e03; wu:fb36g03; YBR0811; YBR088C
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 5111
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 2.0 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P12004
Gene Symbols: Pcna
Immunogen: KLH conjugated synthetic peptide between 231-261 amino acids from the C-terminal region of human PCNA
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PCNA
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Pcna
Gene Alias:
ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; hypothetical protein LOC515499; MGC8367; Pcna; pcna protein; Pcna/cyclin; PCNAR; POL30; Proliferating cell nuclear antigen; wu:fa28e03; wu:fb36g03; YBR0811; YBR088C
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
5111
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
2.0 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P12004
Gene Symbols:
Pcna
Immunogen:
KLH conjugated synthetic peptide between 231-261 amino acids from the C-terminal region of human PCNA
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PCNA
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Pcna
Gene Alias: ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; hypothetical protein LOC515499; MGC8367; Pcna; pcna protein; Pcna/cyclin; PCNAR; POL30; Proliferating cell nuclear antigen; wu:fa28e03; wu:fb36g03; YBR0811; YBR088C
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status: RUO
Gene ID (Entrez): 5111
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 2 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P12004
Gene Symbols: Pcna
Immunogen: KLH conjugated synthetic peptide between 89-117 amino acids from the central region of human PCNA
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PCNA
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Pcna
Gene Alias:
ATLD2; cb16; Cyclin; DNA polymerase delta auxiliary protein; etID36690.10; fa28e03; fb36g03; HGCN8729; hypothetical protein LOC515499; MGC8367; Pcna; pcna protein; Pcna/cyclin; PCNAR; POL30; Proliferating cell nuclear antigen; wu:fa28e03; wu:fb36g03; YBR0811; YBR088C
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status:
RUO
Gene ID (Entrez):
5111
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
2 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P12004
Gene Symbols:
Pcna
Immunogen:
KLH conjugated synthetic peptide between 89-117 amino acids from the central region of human PCNA
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: EBP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Pa2g4
Gene Alias: 38kDa; AA672939; Cell cycle protein p38-2G4 homolog; Ebp1; ErbB-3 binding protein 1; ErbB3-binding protein 1; ErbB3-binding protein Ebp1; hG4 1; hG4-1; IRES-specific cellular trans-acting factor 45 kDa; ITAF45; MGC81621; MGC94070; Mpp1; p38 2G4; p38-2G4; Pa2g4; Plfap; proliferation-associated 2G4; proliferation-associated 2G4, 38kD; proliferation-associated 2G4, 38kDa; proliferation-associated protein 1; Proliferation-associated protein 2G4; protein p38-2G4; si:dz150i12.2; wu:fb19b11; wu:ft56d05; zgc:86732
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 18813, 5036
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration: __
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P50580, Q9UQ80
Gene Symbols: Pa2g4
Immunogen: KLH conjugated synthetic peptide between 228-255 amino acids from the central region of human EBP1
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
EBP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Pa2g4
Gene Alias:
38kDa; AA672939; Cell cycle protein p38-2G4 homolog; Ebp1; ErbB-3 binding protein 1; ErbB3-binding protein 1; ErbB3-binding protein Ebp1; hG4 1; hG4-1; IRES-specific cellular trans-acting factor 45 kDa; ITAF45; MGC81621; MGC94070; Mpp1; p38 2G4; p38-2G4; Pa2g4; Plfap; proliferation-associated 2G4; proliferation-associated 2G4, 38kD; proliferation-associated 2G4, 38kDa; proliferation-associated protein 1; Proliferation-associated protein 2G4; protein p38-2G4; si:dz150i12.2; wu:fb19b11; wu:ft56d05; zgc:86732
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
18813, 5036
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
__
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P50580, Q9UQ80
Gene Symbols:
Pa2g4
Immunogen:
KLH conjugated synthetic peptide between 228-255 amino acids from the central region of human EBP1
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG