PIPA512777

Phospho-TAK1 (Ser192) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA512777-Each-of-1 In Stock ₹ 44,705.10

PIPA512777 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-TAK1 (Ser192)

Classification

Polyclonal

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

O43318

Gene Symbols

MAP3K7

Immunogen

KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S192 of human MAP3K7

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Dot Blot

Conjugate

Unconjugated

Gene

MAP3K7

Gene Alias

B430101B05; C87327; hypothetical protein LOC553788; I79_000697; M3K7; map3k7; map3k7.L; MAPKKK; MEKK7; mitogen activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7 L homeolog; RP1-154G14.1; si:ch211-225h9.1; Tak1; TAK1z; TGF1a; TGF-beta activated kinase 1; TGF-beta-activated kinase 1; TGF-beta-activated kinase TAK1; transforming growth factor beta-activated kinase 1; transforming growth factor-beta-activated kinase 1; XELAEV_18027270mg; xTAK1; zgc:110612

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

6885

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • This antibody is predicted to react with bovine, mouse and rat based on sequence homology
  • TAK1 (also known as MAP3K7), a part of the serine/threonine kinase family, is a versatile protein with many signaling functions
  • Originally identified as a TGF- beta-activated kinase, TAK1 interacts with TGF- beta-receptor and TRAF6 to modulate TGF- beta activation of JNK and p38
  • It has additional roles in activation of p38 and JNK through Wnt, BMP, and activin signaling pathways as well in response to thyroid hormone, osmotic stress, endothelin, and ephrine
  • Through activation of von Hippel-Lindau tumor suppressor expression, TAK1 represses PDGF-B, integrin beta1 and integrin beta5, promoting proper wound healing
  • TAK1 also plays an essential role in IKK activation in numerous signaling pathways including IL-1, IL-6, IL-18, TNF, CD40, TLR, and RIG-I
  • Activation of the TAK1-IKK pathway requires TAB2/3 and ubiquitination
  • In this process, TAB2/3 binds to the C-terminal region of TAK1 and becomes polyubiquitinated, TAK1 is autophosphorylated at Thr178, Thr184, Thr187 and Ser192, and finally TAK1 phosphorylates IKK- beta
  • Additionally, TAK1 represses human telomerase reverse transcriptase suggesting a role in regulation of cell lifespan.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA512777

--


Antigen:
Phospho-TAK1 (Ser192)

Classification:
Polyclonal

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
O43318

Gene Symbols:
MAP3K7

Immunogen:
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S192 of human MAP3K7

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Dot Blot

Conjugate:
Unconjugated

Gene:
MAP3K7

Gene Alias:
B430101B05; C87327; hypothetical protein LOC553788; I79_000697; M3K7; map3k7; map3k7.L; MAPKKK; MEKK7; mitogen activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7 L homeolog; RP1-154G14.1; si:ch211-225h9.1; Tak1; TAK1z; TGF1a; TGF-beta activated kinase 1; TGF-beta-activated kinase 1; TGF-beta-activated kinase TAK1; transforming growth factor beta-activated kinase 1; transforming growth factor-beta-activated kinase 1; XELAEV_18027270mg; xTAK1; zgc:110612

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
6885

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIPA512778

--


Antigen:
Phospho-c-Raf (Thr269)

Classification:
Polyclonal

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P04049

Gene Symbols:
Raf1

Immunogen:
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T269 of human RAF1

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Dot Blot

Conjugate:
Unconjugated

Gene:
Raf1

Gene Alias:
6430402F14Rik; AA990557; BB129353; CMD1NN; CRAF; C-RAF; C-Raf proto-oncogene, serine/threonine kinase; Craf1; Craf1 transforming; D830050J10Rik; EC 2.7.11.1; kinase Raf1; murine leukemia viral (v-raf-1) oncogene homolog 1 (3611-MSV); murine sarcoma 3611 oncogene 1; NS5; Oncogene RAF1; OTTHUMP00000207813; OTTHUMP00000209389; proto-oncogene c-RAF; RAF; raf proto-oncogene serine/threonine protein kinase; RAF proto-oncogene serine/threonine-protein kinase; RAF1; Raf-1; Raf-1 proto-oncogene, serine/threonine kinase; sarcoma 3611 oncogene; v-Raf; v-raf-1 leukemia viral oncogene 1; vraf1 murine le; v-raf-1 murine leukemia viral oncogene homolog 1; v-raf-1 murine leukemia viral oncogene-like protein 1; v-raf-leukemia viral oncogene 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5894

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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PIPA512779

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Antigen:
Phospho-HSP27 (Ser78)

Classification:
Polyclonal

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P04792

Gene Symbols:
HSPB1

Immunogen:
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S78 of human HSPB1

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Dot Blot

Conjugate:
Unconjugated

Gene:
HSPB1

Gene Alias:
27kDa; 28 kDa heat shock protein; CMT2F; DKFZp586P1322; epididymis secretory protein Li 102; estrogen-regulated 24 kDa protein; Growth-related 25 kDa protein; heat shock 25 kDa protein; Heat shock 27 kDa protein; heat shock 27kD protein 1; heat shock 27kDa protein 1; Heat shock protein; heat shock protein 1; heat shock protein 27 kDa beta-1; heat shock protein B1; heat shock protein beta-1; heat shock protein family B (small) member 1; heat shock protein, 25 kDa; heat-shock protein; HEL-S-102; HMN2B; HS; HS.76067; HSP; HSP 25; HSP 27; Hsp25; HSP27; HSP28; HSPB1; p25; Phospho-HSP 27; SRP27; Stress-responsive protein 27; truncated hsp25

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3315

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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PIPA512799

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Antigen:
Phospho-VPS34 (Ser676)

Classification:
Polyclonal

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q8NEB9

Gene Symbols:
Pik3c3

Immunogen:
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S676 of human PI3KC3

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Dot Blot

Conjugate:
Unconjugated

Gene:
Pik3c3

Gene Alias:
5330434F23Rik; catalytic phosphatidylinositol 3-kinase 3; catalytic subunit type 3 Antibody; class 3 phosphoinositide-3-kinase; Class III PI 3-kinase; hVps34; hVps34 Antibody; OTTMUSP00000023341; OTTMUSP00000023350; phosphatidylinositol 3-kinase; Phosphatidylinositol 3-kinase catalytic subunit type 3; phosphatidylinositol 3-kinase p100 subunit; phosphatidylinositol 3-kinase, catalytic subunit type 3; Phosphoinositide-3-kinase class 3; phosphoinositide-3-kinase, class 3; PI3K type 3; PI-3K Vps34p; pi3kc3; PI3-kinase type 3; Pik3c3; PIK3C3 Antibody; PtdIns-3-kinase type 3; VPS34

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5289

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid