PIPA512845

Phospho-TSC2 (Ser939) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA512845-Each-of-1 In Stock ₹ 45,047.34

PIPA512845 - Each of 1

₹ 45,047.34

In Stock

Quantity

1

Base Price: ₹ 45,047.34

GST (18%): ₹ 8,108.521

Total Price: ₹ 53,155.861

Antigen

Phospho-TSC2 (Ser939)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TSC2

Gene Alias

LAM; Nafld; OTTHUMP00000198394; PPP1R160; protein phosphatase 1, regulatory subunit 160; Rc; renal carcinoma; Tcs2; Tsc2; TSC4; Tuberin; tuberous sclerosis 2; tuberous sclerosis 2 homolog protein; tuberous sclerosis 2 protein; Tuberous sclerosis 2 protein homolog

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

7249

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Dot Blot, Immunocytochemistry

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P49815

Gene Symbols

TSC2

Immunogen

KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S939 of human TSC2

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with mouse based on sequence homology
  • TSC2 (Tuberin, Tuberous sclerosis complex, TSC Complex Subunit 2), is implicated as a tumor suppressor and may function in vesicular transport, play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors
  • TSC2 associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin
  • Phosphorylation of tuberin on Ser 939 and Thr 1462 regulates its interaction with hamartin, and is stimulated by various growth factors through the phosphoinositide 3-kinase/Akt pathway
  • TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors
  • Interaction between TSC1 and TSC2 may facilitate vesicular docking
  • TSC2 specifically stimulates the intrinsic GTPase activity of the Ras related protein RAP1A and RAB5, suggesting a possible mechanism for its role in regulating cellular growth
  • Mutations in TSC2 lead to constitutive activation of RAP1A in tumors and are involved in diseases such as lymphangioleiomyomatosis and TSC2 angiomyolipoma
  • Alternative splicing results in transcript variants of three different isoforms of TSC2.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA512845

--


Antigen:
Phospho-TSC2 (Ser939)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TSC2

Gene Alias:
LAM; Nafld; OTTHUMP00000198394; PPP1R160; protein phosphatase 1, regulatory subunit 160; Rc; renal carcinoma; Tcs2; Tsc2; TSC4; Tuberin; tuberous sclerosis 2; tuberous sclerosis 2 homolog protein; tuberous sclerosis 2 protein; Tuberous sclerosis 2 protein homolog

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7249

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Dot Blot, Immunocytochemistry

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P49815

Gene Symbols:
TSC2

Immunogen:
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S939 of human TSC2

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA512858

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Antigen:
Phospho-HGK (Ser629)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP4K4

Gene Alias:
9430080K19Rik; AU043147; AU045934; AW046177; epididymis secretory protein Li 31; FLH21957; FLJ10410; FLJ20373; FLJ90111; HEL-S-31; hepatocyte progenitor kinase-like/germinal center kinase-like kinase; HGK; HPK/GCK-like kinase HGK; KIAA0687; Map4k4; MAPK/ERK kinase kinase kinase 4; MEK kinase kinase 4; MEKKK 4; MEKKK4; mitogen activated protein kinase kinase kinase kinase 4; mitogen-activated protein kinase kinase kinase kinase 4; NCK interacting kinase; nck-interacting kinase; NIK; Ste20 group protein kinase HGK

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9448

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Dot Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
O95819

Gene Symbols:
MAP4K4

Immunogen:
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S629 of human MAP4K4

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA512862

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Antigen:
Phospho-TSC2 (Ser664)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TSC2

Gene Alias:
LAM; Nafld; OTTHUMP00000198394; PPP1R160; protein phosphatase 1, regulatory subunit 160; Rc; renal carcinoma; Tcs2; Tsc2; TSC4; Tuberin; tuberous sclerosis 2; tuberous sclerosis 2 homolog protein; tuberous sclerosis 2 protein; Tuberous sclerosis 2 protein homolog

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7249

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Dot Blot, Immunocytochemistry

Concentration:
__

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P49815

Gene Symbols:
TSC2

Immunogen:
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S664 of human TSC2

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA512867

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Antigen:
Phospho-JNK1 (Thr183)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAPK8

Gene Alias:
AI849689; c-Jun N-terminal kinase 1; FLJ12099; FLJ33785; JNK; JNK1; JNK1 beta1 protein kinase; jnk1a-1; JNK1A2; JNK21B1/2; JNK3; JNK3A; JNK-46; JUN N-terminal kinase; MAP kinase 10; MAP kinase 8; MAPK 10; MAPK 8; MAPK10; Mapk8; mapk8 protein; mapk8b; MGC50974; mitogen activated protein kinase 8; mitogen-activated protein kinase 8; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kinase 8b; MK10; OTTHUMP00000019552; p493F12; p54 gamma; p54bSAPK; Phospho-JNK; PRKM10; PRKM8; protein kinase JNK1; protein kinase mitogen-activated 8; SAPK gamma; SAPK1; SAPK1C; stress-activated protein kinase 1; stress-activated protein kinase 1c; Stress-activated protein kinase JNK1; zgc:112379

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5599

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Dot Blot

Concentration:
__

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P45983

Gene Symbols:
MAPK8

Immunogen:
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T183 of human MAPK8

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG