PIPA513518
Granzyme B Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA513518-Each-of-1 | In Stock | ₹ 47,186.34 |
PIPA513518 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,186.34
GST (18%): ₹ 8,493.541
Total Price: ₹ 55,679.881
Antigen
Granzyme B
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GZMB
Gene Alias
AI553453; C11; Cathepsin G-like 1; CCP1; CCP-1/C11; CCPI; CGL1; CGL-1; CSPB; CSP-B; Ctla1; Ctla-1; CTSGL1; cytotoxic cell protease 1; cytotoxic serine protease B; Cytotoxic T lymphocyte associated serine esterase 1; cytotoxic T-lymphocyte proteinase 2; cytotoxic T-lymphocyte-associated serine esterase 1; fragmentin; fragmentin 2; fragmentin-2; GLP I; GLP III; GLP-1; granzyme 2; granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); granzyme B(G,H); Granzyme-2; GranzymeB; granzyme-like protein 1; granzyme-like protein I; GRB; GZB; Gzmb; HLP; human lymphocyte protein; Human lymphocyte protein (Hlp); Lymphocyte protease; Natural killer cell protease 1; OTTHUMP00000028189; RNKP-1; SECT; T-cell serine protease 1-3E
Host Species
Rabbit
Purification Method
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status
RUO
Gene ID (Entrez)
14939, 3002
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Flow Cytometry, Immunohistochemistry (Paraffin)
Concentration
2 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P04187, P10144
Gene Symbols
GZMB
Immunogen
KLH conjugated synthetic peptide between 2-32 amino acids from the N-terminal region of human GZMB
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Granzyme B is a member of the granzyme serine protease family, and is found in the granules of cytotoxic T cells and NK cells
- Granzyme B has been described as CGL1 (cathepsin G-like-1), a serine protease expressed only in cytotoxic T-lymphocytes after cell activation, and CTLA-1 (cytotoxic T lymphocyte-associated serine esterase 1) based on identification of mRNA in various cytotoxic T cells, but not observed in non-cytotoxic lymphoid cells
- Granzyme B is crucial for the rapid induction of target cell death by apoptosis, induced by interaction with cytotoxic T cells
- The receptor involved in this process has been identified as mannose 6-phosphate receptor which functions as a death receptor for Granzyme B during cytotoxic T cell-induced apoptosis
- Granzyme B enters target cells to cleave caspase-3 and initiate the caspase cascade leading to DNA fragmentation and apoptosis
- Granzyme B can also act through a mitochondrial apoptosis pathway by cleaving the Bid protein
- Granzymes are neutral serine proteases, which are stored in specialized lytic granules of cytotoxic T lymphocytes (CTLs) and in natural killer (NK) cells
- A number of granzymes (A to G) have been isolated and cloned from mouse CTLs and NK cells, however in man, fewer have been cloned and identified.
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Antigen: Granzyme B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GZMB
Gene Alias: AI553453; C11; Cathepsin G-like 1; CCP1; CCP-1/C11; CCPI; CGL1; CGL-1; CSPB; CSP-B; Ctla1; Ctla-1; CTSGL1; cytotoxic cell protease 1; cytotoxic serine protease B; Cytotoxic T lymphocyte associated serine esterase 1; cytotoxic T-lymphocyte proteinase 2; cytotoxic T-lymphocyte-associated serine esterase 1; fragmentin; fragmentin 2; fragmentin-2; GLP I; GLP III; GLP-1; granzyme 2; granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); granzyme B(G,H); Granzyme-2; GranzymeB; granzyme-like protein 1; granzyme-like protein I; GRB; GZB; Gzmb; HLP; human lymphocyte protein; Human lymphocyte protein (Hlp); Lymphocyte protease; Natural killer cell protease 1; OTTHUMP00000028189; RNKP-1; SECT; T-cell serine protease 1-3E
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status: RUO
Gene ID (Entrez): 14939, 3002
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry (Paraffin)
Concentration: 2 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P04187, P10144
Gene Symbols: GZMB
Immunogen: KLH conjugated synthetic peptide between 2-32 amino acids from the N-terminal region of human GZMB
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Granzyme B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GZMB
Gene Alias:
AI553453; C11; Cathepsin G-like 1; CCP1; CCP-1/C11; CCPI; CGL1; CGL-1; CSPB; CSP-B; Ctla1; Ctla-1; CTSGL1; cytotoxic cell protease 1; cytotoxic serine protease B; Cytotoxic T lymphocyte associated serine esterase 1; cytotoxic T-lymphocyte proteinase 2; cytotoxic T-lymphocyte-associated serine esterase 1; fragmentin; fragmentin 2; fragmentin-2; GLP I; GLP III; GLP-1; granzyme 2; granzyme B; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); granzyme B(G,H); Granzyme-2; GranzymeB; granzyme-like protein 1; granzyme-like protein I; GRB; GZB; Gzmb; HLP; human lymphocyte protein; Human lymphocyte protein (Hlp); Lymphocyte protease; Natural killer cell protease 1; OTTHUMP00000028189; RNKP-1; SECT; T-cell serine protease 1-3E
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status:
RUO
Gene ID (Entrez):
14939, 3002
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin)
Concentration:
2 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P04187, P10144
Gene Symbols:
GZMB
Immunogen:
KLH conjugated synthetic peptide between 2-32 amino acids from the N-terminal region of human GZMB
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: SERPINB3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SERPINB3
Gene Alias: HsT1196; LOC483954; Protein T4-A; SCC; SCCA; SCCA1; SCCA-1; SCCA-PD; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3; serine protease inhibitor B3; serpin B3; serpin family B member 3; serpin peptidase inhibitor, clade B (ovalbumin), member 3; serpin peptidase inhibitor, clade B (ovalbumin), member 4; SERPINB3; SERPINB4; spb3; Squamous cell carcinoma antigen 1; SSCA1; T4-A
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status: RUO
Gene ID (Entrez): 6317
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 2 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P29508
Gene Symbols: SERPINB3
Immunogen: KLH conjugated synthetic peptide between 40-69 amino acids from the N-terminal region of human SPB3
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SERPINB3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SERPINB3
Gene Alias:
HsT1196; LOC483954; Protein T4-A; SCC; SCCA; SCCA1; SCCA-1; SCCA-PD; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3; serine protease inhibitor B3; serpin B3; serpin family B member 3; serpin peptidase inhibitor, clade B (ovalbumin), member 3; serpin peptidase inhibitor, clade B (ovalbumin), member 4; SERPINB3; SERPINB4; spb3; Squamous cell carcinoma antigen 1; SSCA1; T4-A
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status:
RUO
Gene ID (Entrez):
6317
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
2 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P29508
Gene Symbols:
SERPINB3
Immunogen:
KLH conjugated synthetic peptide between 40-69 amino acids from the N-terminal region of human SPB3
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Decorin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DCN
Gene Alias: Bone proteoglycan II; CSCD; DC; Dcn; DCN protein; DCN1C; Decorin; decorin isoform a preproprotein; Dermatan sulfate proteoglycan-II; dermatan sulfate proteoglycan-II (decorin); dermatan sulphate proteoglycans II; Dermatan sulphate proteoglycans II (DSPG2); DSPG; DSPG2; mDcn; PG40; PGII; PGS2; PG-S2; proteoglycan core protein; proteoglycan core protein; binds type I collagen fibers and TGF-beta; decoron; similar to bone proteoglycan II; similar to decorin; SLRR1B; Small leucine rich protein 1B; small leucine-rich protein 1B; unnamed protein product
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status: RUO
Gene ID (Entrez): 13179, 1634
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.9 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P07585, P28654
Gene Symbols: DCN
Immunogen: KLH conjugated synthetic peptide between 122-150 amino acids from the central region of human DCN
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Decorin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DCN
Gene Alias:
Bone proteoglycan II; CSCD; DC; Dcn; DCN protein; DCN1C; Decorin; decorin isoform a preproprotein; Dermatan sulfate proteoglycan-II; dermatan sulfate proteoglycan-II (decorin); dermatan sulphate proteoglycans II; Dermatan sulphate proteoglycans II (DSPG2); DSPG; DSPG2; mDcn; PG40; PGII; PGS2; PG-S2; proteoglycan core protein; proteoglycan core protein; binds type I collagen fibers and TGF-beta; decoron; similar to bone proteoglycan II; similar to decorin; SLRR1B; Small leucine rich protein 1B; small leucine-rich protein 1B; unnamed protein product
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status:
RUO
Gene ID (Entrez):
13179, 1634
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.9 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P07585, P28654
Gene Symbols:
DCN
Immunogen:
KLH conjugated synthetic peptide between 122-150 amino acids from the central region of human DCN
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: MRP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ABCC1
Gene Alias: ABC29; ABCC; Abcc1; Abcc1a; Abcc1b; ATP binding cassette subfamily C member 1; ATP-binding cassette sub-family C ( CFTR/MRP) member 1a; ATP-binding cassette sub-family C member 1; ATP-binding cassette transporter variant ABCC1delta-ex13; ATP-binding cassette transporter variant ABCC1delta-ex13&14; ATP-binding cassette transporter variant ABCC1delta-ex25; ATP-binding cassette transporter variant ABCC1delta-ex25&26; ATP-binding cassette, subfamily C (CFTR/MRP), member 1; ATP-binding cassette, sub-family C (CFTR/MRP), member 1; ATP-binding cassette, sub-family C (CFTR/MRP), member 1a; ATP-binding cassette, sub-family C (CFTR/MRP), member 1b; Avcc1a; DKFZp686N04233; DKFZp781G125; Glutathione-S-conjugate-translocating ATPase ABCC1; GS-X; leuk; leukotriene C(4) transporter; LTC4 transporter; Mdrap; MRP; Mrp1; multidrug resistance protein 1; multidrug resistance-associated protein 1; multiple drug resistance-associated protein
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status: RUO
Gene ID (Entrez): 4363
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Flow Cytometry, Western Blot
Concentration: 2 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P33527
Gene Symbols: ABCC1
Immunogen: KLH conjugated synthetic peptide between 1247-1275 amino acids from the C-terminal region of human ABCC1
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MRP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ABCC1
Gene Alias:
ABC29; ABCC; Abcc1; Abcc1a; Abcc1b; ATP binding cassette subfamily C member 1; ATP-binding cassette sub-family C ( CFTR/MRP) member 1a; ATP-binding cassette sub-family C member 1; ATP-binding cassette transporter variant ABCC1delta-ex13; ATP-binding cassette transporter variant ABCC1delta-ex13&14; ATP-binding cassette transporter variant ABCC1delta-ex25; ATP-binding cassette transporter variant ABCC1delta-ex25&26; ATP-binding cassette, subfamily C (CFTR/MRP), member 1; ATP-binding cassette, sub-family C (CFTR/MRP), member 1; ATP-binding cassette, sub-family C (CFTR/MRP), member 1a; ATP-binding cassette, sub-family C (CFTR/MRP), member 1b; Avcc1a; DKFZp686N04233; DKFZp781G125; Glutathione-S-conjugate-translocating ATPase ABCC1; GS-X; leuk; leukotriene C(4) transporter; LTC4 transporter; Mdrap; MRP; Mrp1; multidrug resistance protein 1; multidrug resistance-associated protein 1; multiple drug resistance-associated protein
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status:
RUO
Gene ID (Entrez):
4363
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Flow Cytometry, Western Blot
Concentration:
2 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P33527
Gene Symbols:
ABCC1
Immunogen:
KLH conjugated synthetic peptide between 1247-1275 amino acids from the C-terminal region of human ABCC1
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG