PIPA513597

FOXO1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA513597-Each-of-1 In Stock ₹ 44,705.10

PIPA513597 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

FOXO1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

FOXO1

Gene Alias

Afxh; AI876417; FKH1; FKHR; Fkhr1; forkhead box O1; forkhead box O1 a; forkhead box O1a; forkhead box O1A (rhabdomyosarcoma); forkhead box protein O1; forkhead box protein O1; LOW QUALITY PROTEIN: forkhead box protein O1; forkhead box protein O1A; Forkhead box protein O1-A; Forkhead in rhabdomyosarcoma; forkhead protein 1; forkhead protein FKHR; forkhead, Drosophila, homolog of, in rhabdomyosarcoma; fox family transcription factor FoxO1a.1; FOX01A; foxhead box protein O1-A; foxo1; FOXO1A; FoxO1a.1; member of FKHR-subclass forkhead/winged helix family; zgc:153388

Host Species

Rabbit

Purification Method

Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status

RUO

Gene ID (Entrez)

2308

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration

2 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

Q12778

Gene Symbols

FOXO1

Immunogen

KLH conjugated synthetic peptide between 454-482 amino acids from the central region of human FKHR

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with bovine and porcine based on sequence homology
  • FOXO1 (FKHR, ForKHead Box 01) is a member in a subfamily of the forkhead homeotic gene family of transcription factors
  • Recent experiments have shown that FOXO1 can act as either a coactivator or a corepressor of nuclear receptor activity that is mediated through the LXXLL motif found in the carboxyl terminal region of the FKHR protein
  • Association of FOXO1 with PAX3 has been implicated in alveolar rhabdomyosarcoma
  • Recent studies link the anti-tumor activity of FOXO1, the process of autophagy and myogenic growth and differentiation
  • FOXO1 is the main target of insulin signaling that regulated the metabolic homeostasis in response to oxidative stress
  • FOXO1 binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'- TT[G/A]TTTAC-3'
  • FOXO1 is a regulator of redox balance, osteoblast numbers and controls bone mass
  • Further, FOXO1 orchestrates the endocrine function of the skeleton in regulating glucose metabolism, and suppresses the transcriptional activity of RUNX2, an upstream activator of osteocalcin/BGLAP
  • In hepatocytes, FOXO1 promotes gluconeogenesis by acting together with PPARGC1A to activate the expression of genes such as IGFBP1, G6PC and PPCK1
  • FOXO1 is an important regulator of cell death acting downstream of CDK1, PKB/AKT1 and SKT4/MST1.

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Show Difference

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Thermo Scientific

PIPA513597

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Antigen:
FOXO1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FOXO1

Gene Alias:
Afxh; AI876417; FKH1; FKHR; Fkhr1; forkhead box O1; forkhead box O1 a; forkhead box O1a; forkhead box O1A (rhabdomyosarcoma); forkhead box protein O1; forkhead box protein O1; LOW QUALITY PROTEIN: forkhead box protein O1; forkhead box protein O1A; Forkhead box protein O1-A; Forkhead in rhabdomyosarcoma; forkhead protein 1; forkhead protein FKHR; forkhead, Drosophila, homolog of, in rhabdomyosarcoma; fox family transcription factor FoxO1a.1; FOX01A; foxhead box protein O1-A; foxo1; FOXO1A; FoxO1a.1; member of FKHR-subclass forkhead/winged helix family; zgc:153388

Host Species:
Rabbit

Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status:
RUO

Gene ID (Entrez):
2308

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
2 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q12778

Gene Symbols:
FOXO1

Immunogen:
KLH conjugated synthetic peptide between 454-482 amino acids from the central region of human FKHR

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA513604

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Antigen:
HMGCS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HMGCS1

Gene Alias:
3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase; 3-hydroxy-3-methylglutaryl coenzyme A synthase; 3-hydroxy-3-methylglutaryl-CoA synthase 1; 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble); 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1; 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble); 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) isoform 1; 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) isoform 2; B130032C06Rik; HMG-CoA synthase; HMGCS; Hmgcs1; HMGCS1 protein-like; hydroxymethylglutaryl-CoA synthase 1; hydroxymethylglutaryl-CoA synthase, cytoplasmic; Unknown (protein for IMAGE:7955111)

Host Species:
Rabbit

Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status:
RUO

Gene ID (Entrez):
3157

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
2 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q01581

Gene Symbols:
HMGCS1

Immunogen:
KLH conjugated synthetic peptide between 442-470 amino acids from the C-terminal region of human HMGCS1

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA513605

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Antigen:
Hemopexin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Hpx

Gene Alias:
Beta-1B-glycoprotein; hemopexin; HPX; Hpxn; hx; hyaluronidase

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
15458, 3263

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P02790, Q91X72

Gene Symbols:
Hpx

Immunogen:
KLH conjugated synthetic peptide between 200-227 amino acids from the central region of human HPX

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA513616

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Antigen:
PDIA6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PDIA6

Gene Alias:
1700015E05Rik; AL023058; C77895; CaBP1; CaBP5; Calcium-binding protein 1; endoplasmic reticulum protein 5; ER protein 5; ERP5; P5; PDIA6; pdi-p5; protein disulfide isomerase A6; protein disulfide isomerase associated 6; protein disulfide isomerase family A member 6; protein disulfide isomerase family A, member 6; protein disulfide isomerase P5; protein disulfide isomerase-associated 6; protein disulfide isomerase-related protein; protein disulfide-isomerase A6; thioredoxin domain containing 7; thioredoxin domain containing 7 (protein disulfide isomerase); thioredoxin domain-containing protein 7; TXNDC7

Host Species:
Rabbit

Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status:
RUO

Gene ID (Entrez):
10130

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
__

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q15084

Gene Symbols:
PDIA6

Immunogen:
KLH conjugated synthetic peptide between 236-264 amino acids from the central region of human PDIA6

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG