PIPA5139770

NOTUM Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5139770-Each-of-1 In Stock ₹ 39,785.40

PIPA5139770 - Each of 1

₹ 39,785.40

In Stock

Quantity

1

Base Price: ₹ 39,785.40

GST (18%): ₹ 7,161.372

Total Price: ₹ 46,946.772

Antigen

NOTUM

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NOTUM

Gene Alias

[Wnt protein] O-palmitoleoyl-L-serine hydrolase; 5730593N15Rik; hNOTUM; NOTUM; notum pectinacetylesterase homolog; notum pectinacetylesterase homolog (Drosophila); NOTUM, palmitoleoyl-protein carboxylesterase; OK/SW-CL.30; Palmitoleoyl-protein carboxylesterase NOTUM; protein notum homolog; RGD1307119

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

147111

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry

Concentration

0.05 μg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q6P988

Gene Symbols

NOTUM

Immunogen

Recombinant protein corresponding to Human NOTUM

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Gently mix before use
  • Optimal concentrations and conditions for each application should be determined by the user
  • Immunogen sequence: ANMVFIPYCS SDVWSGASSK SEKNEYAFMG ALIIQEVVRE LLGRGLSGAK VLLLAGSSAG GTGVLLNVDR VAEQLEKLGY PAIQVRGLAD SGWFL Genetic studies in Drosophila have revealed a novel secreted antagonist for Wingless (Wg) signaling, referred to as Notum/Wingful (Wf)
  • Wf/Notum encodes a protein of 430 amino acid residues, which is related to plant pectin acetylesterases of the a/beta-hydrolase superfamily
  • The main target of Notum action appears to be cell surface proteoglycans Dally and/or Dally-like (Dlp)
  • Notum governs the extracellular Wg morphogen distribution via Dally and Dlp
  • Also, like some vertebrate Wnt antagonists, notum expression is activated by Wg signaling, revealing the existence of a feedback control mechanism in which Wg modifies its own gradient distribution
  • In vertebrate, proteoglycans related to Dally and Dlp likely play important roles in Wnt signaling which encodes a glypican that is required for Wnt-11 signaling
  • A single ortholog of Notum exists in the mouse and the human genome, implying that a similar regulatory mechanism may exist in vertebrates.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5139770

--


Antigen:
NOTUM

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NOTUM

Gene Alias:
[Wnt protein] O-palmitoleoyl-L-serine hydrolase; 5730593N15Rik; hNOTUM; NOTUM; notum pectinacetylesterase homolog; notum pectinacetylesterase homolog (Drosophila); NOTUM, palmitoleoyl-protein carboxylesterase; OK/SW-CL.30; Palmitoleoyl-protein carboxylesterase NOTUM; protein notum homolog; RGD1307119

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
147111

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.05 μg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q6P988

Gene Symbols:
NOTUM

Immunogen:
Recombinant protein corresponding to Human NOTUM

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA5139774

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Antigen:
PHF21A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Phf21a

Gene Alias:
80kDa; Bhc; Bhc80; BHC80a; BM-006; Braf35/HDAC complex (Bhc); BRAF35/HDAC2 complex; BRAF35/HDAC2 complex (80 kDa); BRAF35-HDAC complex protein BHC80; D030065N23Rik; KIAA1696; mBHC80; PFTF1; PHD finger protein 21A; Phf21a; RGD1560612

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51317

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.05 μg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q96BD5

Gene Symbols:
Phf21a

Immunogen:
Recombinant protein corresponding to Human PHF21A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA5139776

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Antigen:
TRMT61A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRMT61A

Gene Alias:
6720458F09Rik; AI606093; C14orf172; GCD14; GCD14 and PCMT domain containing protein RGD1359191; GCD14/PCMT domain containing protein RGD1359191; Gcd14p; hTRM61; mRNA methyladenosine-N(1)-methyltransferase catalytic subunit TRMT61A; RGD1359191; TRM61; Trmt61a; tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; tRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRM61; tRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRMT61A; tRNA methyltransferase 61 homolog A; tRNA methyltransferase 61A; tRNA(m1A58)-methyltransferase subunit TRM61; tRNA(m1A58)-methyltransferase subunit TRMT61A; tRNA(m1A58)MTase subunit TRM61; tRNA(m1A58)MTase subunit TRMT61A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
115708

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.05 μg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q96FX7

Gene Symbols:
TRMT61A

Immunogen:
Recombinant protein corresponding to Human TRMT61A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA5139778

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Antigen:
ZNF568

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZNF568

Gene Alias:
LOC100061744; LOW QUALITY PROTEIN: zinc finger protein 568; zinc finger protein 568; ZNF568

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
374900

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.05 μg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q3ZCX4

Gene Symbols:
ZNF568

Immunogen:
Recombinant protein corresponding to Human ZNF568

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG