PIPA5140197

UBXN1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5140197-Each-of-1 In Stock ₹ 39,785.40

PIPA5140197 - Each of 1

₹ 39,785.40

In Stock

Quantity

1

Base Price: ₹ 39,785.40

GST (18%): ₹ 7,161.372

Total Price: ₹ 46,946.772

Antigen

UBXN1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

UBXN1

Gene Alias

2B28; 4930455J02Rik; D19Ertd721e; mY33K; Protein 2B28; RGD1309471; SAKS1; SAPK substrate protein 1; T25529; UBA/UBX 33.3 kDa protein; UBX domain protein 1; UBX domain-containing protein 1; UBXD10; UBXN1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

51035

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

0.1 μg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

Q04323

Gene Symbols

UBXN1

Immunogen

Recombinant protein corresponding to Human UBXN1

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Gently mix before use
  • Optimal concentrations and conditions for each application should be determined by the user
  • Immunogen sequence: KAEELAARQR VREKIERDKA ERAKKYGGSV GSQPPPVAPE PGPVPSSPSQ EPPTKREYDQ CRIQVRLPDG Ubiquitin-binding protein that plays a role in the modulation of innate immune response
  • Blocks both the RIG-I-like receptors (RLR) and NF-kappa-B pathways
  • Following viral infection, UBXN1 is induced and recruited to the RLR component MAVS
  • In turn, interferes with MAVS oligomerization, and disrupts the MAVS/TRAF3/TRAF6 signalosome
  • This function probably serves as a brake to prevent excessive RLR signaling (PubMed:23545497)
  • Interferes with the TNFalpha-triggered NF-kappa-B pathway by interacting with cellular inhibitors of apoptosis proteins (cIAPs) and thereby inhibiting their recruitment to TNFR1 (PubMed:25681446)
  • Prevents also the activation of NF-kappa-B by associating with CUL1 and thus inhibiting NF-kappa-B inhibitor alpha/NFKBIA degradation that remains bound to NF-kappa-B (PubMed:28152074)
  • Interacts with the BRCA1-BARD1 heterodimer and regulates its activity
  • Specifically binds 'Lys-6'-linked polyubiquitin chains
  • Interaction with autoubiquitinated BRCA1 leads to the inhibition of the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer (PubMed:20351172)
  • Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol
  • [UniProt]

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5140197

--


Antigen:
UBXN1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
UBXN1

Gene Alias:
2B28; 4930455J02Rik; D19Ertd721e; mY33K; Protein 2B28; RGD1309471; SAKS1; SAPK substrate protein 1; T25529; UBA/UBX 33.3 kDa protein; UBX domain protein 1; UBX domain-containing protein 1; UBXD10; UBXN1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51035

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.1 μg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q04323

Gene Symbols:
UBXN1

Immunogen:
Recombinant protein corresponding to Human UBXN1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA5140198

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Antigen:
C9orf114

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPOUT1

Gene Alias:
9930028P05; AL033358; C9orf114; CENP-32; Centromere protein 32; D2Wsu81e; DNA segment, Chr 2, Wayne State University 81, expressed; HSPC109; Kinetochore-associated protein; LOC499770; Putative methyltransferase C9orf114; putative methyltransferase C9orf114 homolog; similar to LOC495800 protein; SPOUT domain containing methyltransferase 1; SPOUT domain-containing methyltransferase 1; Spout1; uncharacterized protein C9orf114 homolog

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51490

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.3 μg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q5T280

Gene Symbols:
SPOUT1

Immunogen:
Recombinant protein corresponding to Human SPOUT1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA5140199

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Antigen:
MAP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MOAP1

Gene Alias:
AA987038; MAP1; Map-1; Moap1; Modulator of apoptosis 1; paraneoplastic antigen like 4; paraneoplastic antigen Ma4; paraneoplastic Ma antigen family member 4; PNMA4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
64112

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.1 μg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q96BY2

Gene Symbols:
MOAP1

Immunogen:
Recombinant protein corresponding to Human MOAP1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA5140200

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Antigen:
SPATA9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SPATA9

Gene Alias:
CTD-2154I11.2; NYD-SP16; SPATA9; spermatogenesis associated 9; spermatogenesis-associated protein 9; testicular tissue protein Li 179; testis development protein NYD-SP16

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
83890

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.3 μg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9BWV2

Gene Symbols:
SPATA9

Immunogen:
Recombinant protein corresponding to Human SPATA9

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG