PIPA5141149

AIRE Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5141149-Each-of-1 In Stock ₹ 40,127.64

PIPA5141149 - Each of 1

₹ 40,127.64

In Stock

Quantity

1

Base Price: ₹ 40,127.64

GST (18%): ₹ 7,222.975

Total Price: ₹ 47,350.615

Antigen

AIRE

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Aire

Gene Alias

Aire; AIRE protein; AIRE1; APECED; APECED protein; APECED protein homolog; APS1; APSI; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog; Autoimmune regulator; autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy); autoimmune regulator AIRE1a; LOW QUALITY PROTEIN: autoimmune regulator; OTTHUMP00000109529; PGA1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11634

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.2% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q9Z0E3

Gene Symbols

Aire

Immunogen

Synthetic peptide corresponding to Human Autoimmune regulator aa 503-552/552 mouse.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse

Form

Liquid

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Description

  • AIRE is a transcriptional regulator protein that binds to DNA as a dimer and tetramer, but not as a monomer, and may be involved in the regulation of gene expression
  • A nuclear protein, AIRE is a 545 amino acid protein with an HSR domain, two PHD type zinc fingers, and a SAND domain, and may be present in soluble high-molecular-weight complexes
  • It may form homodimer, homotetramer and also nuclear bodies and interacts with the transcriptional coactivator CBP and CREBBP
  • Three isoforms of AIRE are reported and one of them is predicted to be a candidate for nuclear-mediated decay (NMD)
  • AIRE is involved in immune regulation and is known to mediate E3 ubiquitin ligase activity
  • Defects in AIRE are responsible for the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5141149

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Antigen:
AIRE

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Aire

Gene Alias:
Aire; AIRE protein; AIRE1; APECED; APECED protein; APECED protein homolog; APS1; APSI; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog; Autoimmune regulator; autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy); autoimmune regulator AIRE1a; LOW QUALITY PROTEIN: autoimmune regulator; OTTHUMP00000109529; PGA1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11634

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q9Z0E3

Gene Symbols:
Aire

Immunogen:
Synthetic peptide corresponding to Human Autoimmune regulator aa 503-552/552 mouse.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Img

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PIPA5141150

--


Antigen:
CELSR2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CELSR2

Gene Alias:
ADGRC2; adhesion G protein-coupled receptor C2; cadherin EGF LAG seven-pas G-type receptor 2; cadherin EGF LAG seven-pass G-type receptor 2; Cadherin family member 10; cadherin, EGF LAG seven-pass G-type receptor 2; cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila); CDHF10; Celsr2; EGFL2; EGF-like protein 2; EGF-like-domain, multiple 2; epidermal growth factor-like 2; epidermal growth factor-like protein 2; flamingo; Flamingo homolog; flamingo homolog 3; Flamingo1; flamingo-like protein celsr2; FLJ34118; FLJ42737; FLJ45143; FLJ45845; KIAA0279; MEGF3; mfmi1; mKIAA0279; Multiple EGF-like domains protein 3; multiple epidermal growth factor-like domains 3; multiple epidermal growth factor-like domains protein 3; seven-pass transmembrane cadherin

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1952, 53883

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q9HCU4, Q9R0M0

Gene Symbols:
CELSR2

Immunogen:
Synthetic peptide within Human Cadherin EGF LAG seven-pass G-type receptor 2 aa 21-70/2,923.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

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PIPA5141152

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Antigen:
DCHS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DCHS1

Gene Alias:
Cadherin-19; cadherin-25; cadherin-related family member 6; CDH19; CDH25; CDHR6; dachsous cadherin-related 1; DCHS1; FIB1; fibroblast cadherin 1; fibroblast cadherin FIB1; Fibroblast cadherin-1; KIAA1773; MVP2; PCDH16; Protein dachsous homolog 1; protocadherin-16; VMLDS1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8642

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q96JQ0

Gene Symbols:
DCHS1

Immunogen:
Synthetic peptide within Human Protocadherin-16 aa 624-673/3,298.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

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PIPA5141155

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Antigen:
TMEM67

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TMEM67

Gene Alias:
5330408M12Rik; B230117O07; b2b1163.1Clo; b2b1291.1Clo; JBTS6; meckel syndrome type 3 protein; Meckel syndrome type 3 protein homolog; Meckelin; Mks3; NPHP11; TMEM67; TNEM67; transmembrane protein 67

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
329795, 91147

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q5HYA8, Q8BR76

Gene Symbols:
TMEM67

Immunogen:
Synthetic peptide within human Meckelin aa 20-80.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid