PIPA5141979

SOCS1 Polyclonal Antibody, Biotin, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5141979-Each-of-1 In Stock ₹ 38,758.68

PIPA5141979 - Each of 1

₹ 38,758.68

In Stock

Quantity

1

Base Price: ₹ 38,758.68

GST (18%): ₹ 6,976.562

Total Price: ₹ 45,735.242

Antigen

SOCS1

Classification

Polyclonal

Conjugate

Biotin

Gene

Socs1

Gene Alias

CIS1; Cish1; Cish7; cytokine inducible SH2-containing protein 1; cytokine inducible SH2-containing protein 7; cytokine-inducible SH2 protein 1; JAB; JAK binding protein; JAK2-binding protein; JAK-binding protein; Socs1; SOCS-1; SSI1; SSI-1; STAT induced SH3 protein 1; STAT-induced STAT inhibitor 1; Suppressor of cytokine signaling 1; Tec-interacting protein 3; TIP3; TIP-3

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

12703, 8651

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

O15524, O35716

Gene Symbols

Socs1

Immunogen

Peptide with sequence C-VLRDYLSSFPFQI.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Form

Liquid

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Description

  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000
  • The Suppressor of cytokine signaling (SOCS) and cytokine-inducible SH2 proteins are a family of intracellular proteins which regulate the immune cell responses to cytokines
  • SOCS1 acts to suppress dendritic cell (DC) as well as T cell hyperactivation following cytokine signaling by inhibiting JAK tyrosine kinase, a kinase necessary for type I and II cytokine receptors to initiate signaling, by directly binding to the catalytic domain of the kinase
  • SOCS1 also possesses E3 ubiquitin protein ligase activity that results in the polyubiquitination of its target proteins and subsequent degradation by the proteosome
  • It is through this method that SOCS1 negatively regulates signaling by Toll-like receptors TLR2 and TLR4 by mediating the degradation of the TLR signaling adaptor protein TIRAP.

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Thermo Scientific

PIPA5141979

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Antigen:
SOCS1

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
Socs1

Gene Alias:
CIS1; Cish1; Cish7; cytokine inducible SH2-containing protein 1; cytokine inducible SH2-containing protein 7; cytokine-inducible SH2 protein 1; JAB; JAK binding protein; JAK2-binding protein; JAK-binding protein; Socs1; SOCS-1; SSI1; SSI-1; STAT induced SH3 protein 1; STAT-induced STAT inhibitor 1; Suppressor of cytokine signaling 1; Tec-interacting protein 3; TIP3; TIP-3

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
12703, 8651

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O15524, O35716

Gene Symbols:
Socs1

Immunogen:
Peptide with sequence C-VLRDYLSSFPFQI.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

Img

Thermo Scientific

PIPA5141982

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Antigen:
DAPP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DAPP1

Gene Alias:
b lymphocyte adapter protein Bam32; Bam32; B-cell adapter molecule of 32 kDa; Dapp1; Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide; dual adaptor for phosphotyrosine and 3-phosphoinositides 1; dual adaptor of phosphotyrosine and 3-phosphoinositides; dual adaptor of phosphotyrosine and 3-phosphoinositides 1; hDAPP1; HSPC066; mDAPP1

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
27071

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9UN19

Gene Symbols:
DAPP1

Immunogen:
Peptide with sequence SALCISPEEKTDHK.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

Thermo Scientific

PIPA5141985

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Antigen:
CSK

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
CSK

Gene Alias:
AW212630; CSK; CSK, non-receptor tyrosine kinase; C-SRC kinase; c-src tyrosine kinase; C-terminal Src kinase; MGC117393; p50CSK; protein-tyrosine kinase (CSK); protein-tyrosine kinase CYL; Protein-tyrosine kinase MPK-2; Tyrosine-protein kinase CSK

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
12988, 1445, 315707

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P32577, P41240, P41241

Gene Symbols:
CSK

Immunogen:
Peptide with sequence CEQLEHIKTHELHL.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

Thermo Scientific

PIPA5141991

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Antigen:
TSPYL2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TSPYL2

Gene Alias:
CASK interacting nucleosome assembly protein; CASK-interacting nucleosome assembly protein; CDA1; Cell division autoantigen 1; cell division autoantigen 1 nucleolar protein; CINAP; CTCL; CTCL tumor antigen se20-4; CTCL-associated antigen se20-4; Cutaneous T-cell lymphoma-associated antigen se20-4; cutaneous T-cell lymphoma-associated tumor antigen se20-4; DENTT; differentially expressed nucleolar TGF-beta1 target; differentially-expressed nucleolar TGF-beta1 target protein; DXBwg1396e; DXHXS1008E; E130307F10Rik; HRIHFB2216; NP79; nuclear protein of 79 kDa; nucleolar TGF-beta1 target protein; RGD1563283; RP1-290F12.2; SE204; testis-specific protein Y encoded-like 2; testis-specific Y-encoded-like protein 2; TSPX; TSPY like 2; Tspyl2; TSPY-like 2; TSPY-like protein 2

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
64061

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin)

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9H2G4

Gene Symbols:
TSPYL2

Immunogen:
Peptide with sequence C-PNGWANPGKRGKTG.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid