PIPA5142205

CDKN2A (Isoform 3) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5142205-Each-of-1 In Stock ₹ 38,758.68

PIPA5142205 - Each of 1

₹ 38,758.68

In Stock

Quantity

1

Base Price: ₹ 38,758.68

GST (18%): ₹ 6,976.562

Total Price: ₹ 45,735.242

Antigen

CDKN2A (Isoform 3)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CDKN2A

Gene Symbols

CDKN2A

Immunogen

Peptide with sequence C-ILRKKGRLPGEFSE.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

P42771

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

1029

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

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Description

  • Additional Information: This antibody is expected to recognize the pancreas isoform (NP_478104.1) only
  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000
  • This gene generates several transcript variants which differ in their first exons
  • At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase
  • The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants
  • This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, the E3 ubiquitin-protein ligase MDM2, a protein responsible for the degradation of p53
  • In spite of the structural and functional differences, the CDK inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control
  • This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene
  • [provided by RefSeq, Sep 2012]

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5142205

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Antigen:
CDKN2A (Isoform 3)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDKN2A

Gene Symbols:
CDKN2A

Immunogen:
Peptide with sequence C-ILRKKGRLPGEFSE.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P42771

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
1029

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Img

Thermo Scientific

PIPA5142209

--


Antigen:
PARP12

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PARP12

Gene Symbols:
PARP12

Immunogen:
Peptide with sequence C-NAHDIKNKSSAP.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9H0J9

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
64761

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Img

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PIPA5142210

--


Antigen:
Prostaglandin E Receptor EP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ptger1

Gene Symbols:
Ptger1

Immunogen:
Peptide with sequence C-DSRRRWGAHGPRS.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P34995

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
5731

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Img

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PIPA5142212

--


Antigen:
PRODH

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Prodh

Gene Symbols:
Prodh

Immunogen:
Peptide with sequence C-ERDGSGTNKRDKQYQ.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O43272

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
5625

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG