PIPA5142275

MYLK Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5142275-Each-of-1 In Stock ₹ 38,758.68

PIPA5142275 - Each of 1

₹ 38,758.68

In Stock

Quantity

1

Base Price: ₹ 38,758.68

GST (18%): ₹ 6,976.562

Total Price: ₹ 45,735.242

Antigen

MYLK

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MYLK

Gene Alias

155 kda myosin light chain kinase homolog; 9530072E15Rik; A clone isolated from a chicken gizzard cDNA library which has high homology with the 3'-end sequence of the chicken gizzard myosin light chain kinase (MLCK) cDNA; The 5'-leader seqeuence derives from the intronic sequence of the MLCK gene.; A930019C19Rik; AAT7; AW489456; kinase related protein; kinase-related protein; KRP; KRP/Telokin; MLCK; MLCK1; MLCK108; MLCK210; MSTP083; mylk; MYLK1; myosin light chain kinase; myosin light chain kinase, smooth muscle; Myosin light chain kinase, smooth muscle, deglutamylated form; myosin, light polypeptide kinase; nmMlck; smMLCK; smooth muscle myosin light chain kinase; smooth muscle myosin light chain kinase (61-kDa active fragment); smooth muscle myosin light chain kinase precursor (EC 2.7.2.37); telokin; unnamed protein product

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

4638

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q15746

Gene Symbols

MYLK

Immunogen

Peptide with sequence C-KDTKNMEAKKLSKD.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

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Description

  • Additional Information: This antibody is expected to recognise all reported isoforms (NP_444253.3; NP_444254.3 ; NP_444255.3 and NP_444256.3)
  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000
  • MYLK (MLCK) is a serine/threonine kinase that phosphorylates myosin regulatory light chains to assist in the production of contractile activity (myosin-actin interaction)
  • MLCK is responsible for smooth muscle contraction via phosphorylation of a specific serine in the N-terminus of myosin light chains (MLC), an event that facilitates myosin interaction with actin filaments
  • It is a central determinant in the development of vascular permeability and tissue edema formation
  • In the nervous system it has been shown to control the growth initiation of astrocytic processes in culture and to participate in transmitter release at synapses formed between cultured sympathetic ganglion cells
  • MLCK acts as a critical participant in signaling sequences that result in fibroblast apoptosis
  • Smooth muscle and non-muscle isozymes are expressed in a wide variety of adult and fetal tissues and in cultured endothelium with qualitative expression appearing to be neither tissue- nor development-specific
  • Non-muscle isoform 2 is the dominant splice variant expressed in various tissues
  • The Telokin isoform, which binds calmodulin, has been found in a wide variety of adult and fetal tissues
  • MLCK is probably down-regulated by phosphorylation
  • The protein contains 1 fibronectin type III domain and 9 immunoglobulin-like C2-type domains.

Compare Similar Items

Show Difference

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PIPA5142275

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Antigen:
MYLK

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MYLK

Gene Alias:
155 kda myosin light chain kinase homolog; 9530072E15Rik; A clone isolated from a chicken gizzard cDNA library which has high homology with the 3'-end sequence of the chicken gizzard myosin light chain kinase (MLCK) cDNA; The 5'-leader seqeuence derives from the intronic sequence of the MLCK gene.; A930019C19Rik; AAT7; AW489456; kinase related protein; kinase-related protein; KRP; KRP/Telokin; MLCK; MLCK1; MLCK108; MLCK210; MSTP083; mylk; MYLK1; myosin light chain kinase; myosin light chain kinase, smooth muscle; Myosin light chain kinase, smooth muscle, deglutamylated form; myosin, light polypeptide kinase; nmMlck; smMLCK; smooth muscle myosin light chain kinase; smooth muscle myosin light chain kinase (61-kDa active fragment); smooth muscle myosin light chain kinase precursor (EC 2.7.2.37); telokin; unnamed protein product

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
4638

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q15746

Gene Symbols:
MYLK

Immunogen:
Peptide with sequence C-KDTKNMEAKKLSKD.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

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PIPA5142276

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Antigen:
RPL8

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
Rpl8

Gene Alias:
60S ribosomal protein L8; hypothetical protein LOC535056; L8; Large ribosomal subunit protein uL2; ribosomal protein L8; rpl8; zgc:73105; zgc:77641

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
6132

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P62917

Gene Symbols:
Rpl8

Immunogen:
Peptide with sequence KAGRAYHKYKAKRNC.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

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PIPA5142277

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Antigen:
HYAL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HYAL1

Gene Alias:
Hya1; HYAL1; Hyal-1; Hyaluronidase; hyaluronidase 1; hyaluronidase-1; hyaluronoglucosaminidase 1; hyaluronoglucosaminidase-1; LUCA1; LuCa-1; Lung carcinoma protein 1; MPS9; NAT6; plasma hyaluronidase; tumor suppressor LUCA-1

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
3373

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin)

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q12794

Gene Symbols:
HYAL1

Immunogen:
Peptide with sequence ENTRTKESCQAIKEY.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

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PIPA5142280

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Antigen:
IDE

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
IDE

Gene Alias:
1300012G03Rik; 4833415K22Rik; AA675336; Abeta-degrading protease; AI507533; FLJ35968; Ide; INSDEGM; Insulin degrading enzyme; insulin protease; insulinase; Insulin-degrading enzyme; Insulysin; zgc:162603

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
3416

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P14735

Gene Symbols:
IDE

Immunogen:
Peptide with sequence CQQYNFDRDNTE.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid