PIPA5142308

TREX2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5142308-Each-of-1 In Stock ₹ 38,758.68

PIPA5142308 - Each of 1

₹ 38,758.68

In Stock

Quantity

1

Base Price: ₹ 38,758.68

GST (18%): ₹ 6,976.562

Total Price: ₹ 45,735.242

Antigen

TREX2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TREX2

Gene Alias

3'-5' exonuclease TREX2; 3'-5' exonuclease TREX2 long form; RGD1562245; Three prime repair exonuclease 2; Trex2

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

11219

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q9BQ50

Gene Symbols

TREX2

Immunogen

Peptide with sequence C-HRSSLENPEHDES.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

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Description

  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000
  • TREX2 is one of two major human 3' to 5' exonucleases which are required for checkpoint signaling after DNA damage
  • While the related protein TREX1 is required for ATR expression and mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis, less is known about TREX2
  • Like TREX1, TREX2 is ubiquitously expressed in all tissues examined
  • X-ray crystallography studies of TREX2-single strand DNA complexes revealed that TREX2 binds DNA as a dimer and may act to displace the second DNA strand, suggesting that TREX2 unzips and denatures double stranded DNA and feed the substrate DNA strand into the TREX2 active site
  • At least two isoforms of TREX2 are known to exist.

Compare Similar Items

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Thermo Scientific

PIPA5142308

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Antigen:
TREX2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TREX2

Gene Alias:
3'-5' exonuclease TREX2; 3'-5' exonuclease TREX2 long form; RGD1562245; Three prime repair exonuclease 2; Trex2

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
11219

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9BQ50

Gene Symbols:
TREX2

Immunogen:
Peptide with sequence C-HRSSLENPEHDES.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

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PIPA5142309

--


Antigen:
EPB41L4B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EPB41L4B

Gene Alias:
6430543G08Rik; AA589614; AU021054; band 4.1-like protein 4B; BB007528; CG1; D4Ertd346e; Ehm2; Epb4.1l4b; EPB41L4B; erythrocyte membrane protein band 4.1 like 4B; erythrocyte protein band 4.1 like 4b; erythrocyte protein band 4.1-like 4b; erythrocyte protein band 4.1-like 4b; expressed in high-metastatic cells; expressed in high-metastatic cells; FERM-containing protein CG1; LULU2; Protein EHM2; RGD1562988

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
54566

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9H329

Gene Symbols:
EPB41L4B

Immunogen:
Peptide with sequence C-HNYQPQYHPNIHPSQ.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

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PIPA5142312

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Antigen:
TEB4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MARCHF6

Gene Alias:
3830408G03; 6-Mar; DOA10; doa10 homolog; E3 ubiquitin-protein ligase MARCH6; F830029L24Rik; KIAA0597; MARCH6; MARCH-VI; membrane associated ring finger 6; membrane associated ring-CH-type finger 6; membrane-associated ring finger (C3HC4) 6; membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase; membrane-associated RING finger protein 6; membrane-associated RING-CH finger protein 6; membrane-associated RING-CH protein VI; mKIAA0597; Protein TEB-4; RING finger protein 176; RING-type E3 ubiquitin transferase MARCH6; RNF176; TEB4

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
10299

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin)

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O60337

Gene Symbols:
MARCHF6

Immunogen:
Peptide with sequence C-QRLVNYERKSGKQ.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

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PIPA5142313

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Antigen:
ERCC1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ERCC1

Gene Alias:
COFS4; DNA excision repair protein ERCC-1; ERCC excision repair 1, endonuclease non-catalytic subunit; Ercc1; Ercc-1; excision repair cross-complementation group 1; excision repair cross-complementing 1; excision repair cross-complementing rodent repair deficiency, complementation group 1; excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence); hypothetical protein LOC405807; RAD10; UV20; zgc:77511

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
2067

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunocytochemistry

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P07992

Gene Symbols:
ERCC1

Immunogen:
Peptide with sequence C-QVDVKDPQQALKE.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid