PIPA5142457

CXXC4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5142457-Each-of-1 In Stock ₹ 38,758.68

PIPA5142457 - Each of 1

₹ 38,758.68

In Stock

Quantity

1

Base Price: ₹ 38,758.68

GST (18%): ₹ 6,976.562

Total Price: ₹ 45,735.242

Antigen

CXXC4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CXXC4

Gene Alias

9330210J02Rik; C030003J12Rik; CXXC finger 4; CXXC finger protein 4; CXXC4; CXXC-type zinc finger protein 4; Dvl-binding protein IDAX (inhibition of the Dvl and Axin complex); Idax; inhibition of the Dvl and axin complex protein; inhibitor of the Dvl and Axin complex

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

80319

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Applications

Immunohistochemistry (Paraffin)

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q9H2H0

Gene Symbols

CXXC4

Immunogen

Peptide with sequence C-GTSLERTPVPSAEA.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

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Description

  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000
  • Preliminary analysis showed no signal in Western Blot
  • CXXC4 is zinc finger protein that binds directly to the PDZ domain of DVL1, a protein involved in the Wnt signaling pathway, through its C-terminal region
  • CXXC4 interaction with DVL1 competes with DVL1-AXIN binding, although the affinity of DVL1 for CXXC4 is lower than that for AXIN
  • In mouse fibroblasts, CXXC4 suppressed Wnt3a induction of beta-catenin and inhibited Wnt3a-dependent TCF4 activation, suggesting that CXXC4 acts as a negative regulator of the Wnt signaling pathway and functions between DVL and beta-catenin
  • Recent reports suggest that decreased CXXC4 expression is associated with kidney cancer metastasis, cell proliferation, reduced apoptosis in response to cancer drugs, and upregulation of genes involved with proliferation, invasion and cell survival, suggesting that CXXC4 plays a critical role in tumor progression in kidney cancer.

Compare Similar Items

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Thermo Scientific

PIPA5142457

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Antigen:
CXXC4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CXXC4

Gene Alias:
9330210J02Rik; C030003J12Rik; CXXC finger 4; CXXC finger protein 4; CXXC4; CXXC-type zinc finger protein 4; Dvl-binding protein IDAX (inhibition of the Dvl and Axin complex); Idax; inhibition of the Dvl and axin complex protein; inhibitor of the Dvl and Axin complex

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
80319

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin)

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9H2H0

Gene Symbols:
CXXC4

Immunogen:
Peptide with sequence C-GTSLERTPVPSAEA.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

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PIPA5142459

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Antigen:
ATG4D

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Atg4d

Gene Alias:
9830134P12Rik; APG4 (ATG4) autophagy-related homolog D; APG4 autophagy 4 homolog D; APG4D; APG4-D; ATG4 autophagy related 4 homolog D; Atg4d; Atg4dl; Autl4; AUT-like 4 cysteine endopeptidase; AUT-like 4, cysteine endopeptidase; Autophagin-4; autophagy related 4D cysteine peptidase; autophagy related 4D, cysteine peptidase; autophagy-related 4D; autophagy-related cysteine endopeptidase 4; Autophagy-related protein 4 homolog D; cysteine protease ATG4D; Cysteine protease ATG4D, mitochondrial; cysteine protease involved in autophagy; cysteine protease involved in autophagy APG4-D

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
84971

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q86TL0

Gene Symbols:
Atg4d

Immunogen:
Peptide with sequence CSQLAQPTLRLPRT.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

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PIPA5142460

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Antigen:
ATG4C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATG4C

Gene Alias:
APG4 (ATG4) autophagy-related homolog C; APG4 autophagy 4 homolog C; APG4C; APG4-C; ATG4 autophagy related 4 homolog C; ATG4C; Atg4cl; AUTL1; AUTL3; AUT-like 1, cysteine endopeptidase; AUT-like 3 cysteine endopeptidase; autophagin 3; autophagin-3; autophagy related 4C cysteine peptidase; autophagy related 4C, cysteine peptidase; autophagy-related 4C; autophagy-related cysteine endopeptidase 3; Autophagy-related protein 4 homolog C; cysteine peptidase; cysteine protease ATG4C; cysteine protease involved in autophagy; FLJ14867

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
84938

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q96DT6

Gene Symbols:
ATG4C

Immunogen:
Peptide with sequence C-EDEKKQLKRFSTEE.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

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PIPA5142461

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Antigen:
FZD4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FZD4

Gene Alias:
CD344; CD344 antigen; EVR1; FEVR; frizzled 4, seven transmembrane spanning receptor; frizzled class receptor 4; frizzled family receptor 4; frizzled homolog 4; frizzled homolog 4 (Drosophila); frizzled receptor 4; frizzled-4; Fz4; Fz-4; Fzd4; FZD4S; FzE4; GPCR; hFz4; mFz4; MGC34390; rFz4; WNT receptor frizzled-4

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
8322

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin)

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9ULV1

Gene Symbols:
FZD4

Immunogen:
Peptide with sequence C-KIRSNLQKDGTKT.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid