PIPA5142503

SKA3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5142503-Each-of-1 In Stock ₹ 38,758.68

PIPA5142503 - Each of 1

₹ 38,758.68

In Stock

Quantity

1

Base Price: ₹ 38,758.68

GST (18%): ₹ 6,976.562

Total Price: ₹ 45,735.242

Antigen

SKA3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SKA3

Gene Alias

C13orf3; F630043A04Rik; RAMA1; RGD1307201; RP11-101P17.12-002; Ska3; spindle and kinetochore associated complex subunit 3; spindle and kinetochore-associated protein 3

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

221150

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q8IX90

Gene Symbols

SKA3

Immunogen

Peptide with sequence C-PLSKTNSSSNDLE.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

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Description

  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000
  • Upon entry into mitosis, the cell's microtubule (MT) network forms the mitotic spindle, allowing the segregation of paired chromosomes
  • Proteinaceous structures on centromeric chromatin termed kinetochores (KT) are essential for the proper attachment of the chromosomes to the spindle MTs
  • A recently discovered spindle and kinetochore complex, comprised of proteins SKA1, SKA2, and SKA3, has been found to be required for stable KT-MT interactions and timely anaphase onset
  • Like with SKA1 or SKA2, depletion of SKA3 by siRNA delays anaphase transition, resulting in a prolonged a metaphase-like state
  • These SKA3-depleted cells accumulate high levels of the checkpoint protein Bub1 at kinetochores, suggesting the SKA complex plays a key role in spindle checkpoint silencing and the maintenance of chromosome cohesion in mitosis.

Compare Similar Items

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Thermo Scientific

PIPA5142503

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Antigen:
SKA3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SKA3

Gene Alias:
C13orf3; F630043A04Rik; RAMA1; RGD1307201; RP11-101P17.12-002; Ska3; spindle and kinetochore associated complex subunit 3; spindle and kinetochore-associated protein 3

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
221150

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q8IX90

Gene Symbols:
SKA3

Immunogen:
Peptide with sequence C-PLSKTNSSSNDLE.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

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PIPA5142504

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Antigen:
TPCN2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TPCN2

Gene Alias:
BC025890; D830047E22Rik; SHEP10; Tpc2; TPCN2; Two pore calcium channel protein 2; two pore segment channel 2; two-pore calcium channel protein 2; voltage-dependent calcium channel protein TPC2

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
219931

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q8NHX9

Gene Symbols:
TPCN2

Immunogen:
Peptide with sequence C-EDELTERLSQHPH.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Img

Thermo Scientific

PIPA5142508

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Antigen:
MNT

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MNT

Gene Alias:
BHLHD3; Class D basic helix-loop-helix protein 3; MAD6; max binding protein; MAX network transcriptional repressor; max-binding protein MNT; Max-interacting protein; MNT; MNT, MAX dimerization protein; MXD6; Myc antagonist MNT; Protein ROX; Rox

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
17428

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O08789

Gene Symbols:
MNT

Immunogen:
Peptide with sequence C-DQASTSTASEGEDNI.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

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PIPA5142509

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Antigen:
UBR2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
UBR2

Gene Alias:
9930021A08Rik; AI462103; AW540746; bA49A4.1; C6orf133; dJ242G1.1; dJ392M17.3; E130209G04Rik; E3 ubiquitin-protein ligase UBR2; Kiaa0349; mKIAA0349; N-recognin-2; RING-type E3 ubiquitin transferase UBR2; si:ch211-239i4.2; ubiquitin ligase E3 alpha-II; ubiquitin protein ligase E3 component n-recognin 2; ubiquitin-protein ligase E3-alpha-2; Ubiquitin-protein ligase E3-alpha-II; Ubr2

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
23304

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q8IWV8

Gene Symbols:
UBR2

Immunogen:
Peptide with sequence SCPKSGGDKSRAPT.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid