PIPA5142731

ERO1L Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5142731-Each-of-1 In Stock ₹ 38,758.68

PIPA5142731 - Each of 1

₹ 38,758.68

In Stock

Quantity

1

Base Price: ₹ 38,758.68

GST (18%): ₹ 6,976.562

Total Price: ₹ 45,735.242

Antigen

ERO1L

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ERO1A

Gene Alias

Endoplasmic oxidoreductin-1-like protein; endoplasmic reticulum oxidation 1; endoplasmic reticulum oxidoreductase 1 alpha; endoplasmic reticulum oxidoreductase alpha; Endoplasmic reticulum oxidoreductin-1-like protein; ero1; ERO1A; Ero1alpha; ERO1-alpha; ERO1L; ERO1-L; ERO1LA; ERO1-L-alpha; ERO1-like; ERO1-like (S. cerevisiae); ERO1-like protein alpha; Giig11; Global ischemia-induced protein 11; oxidoreductin-1-L-alpha; UNQ434/PRO865

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

30001

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q96HE7

Gene Symbols

ERO1A

Immunogen

Peptide with sequence C-QSDEVPDGIKSASY.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

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Description

  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000
  • ERO1L (endoplasmic oxidoreductin-1-like protein) is localized in ER membrane as peripheral membrane protein on the lumenal side
  • Its association with ERP44 is essential for its retention in the ER and is unique in coupling oxygen reduction to de novo disulfides formation
  • The ERO1L enzyme is broadly distributed at low levels in several tissues with highest levels in the upper digestive tract and is stimulated by hypoxia via HIF-signaling
  • ERO1L generally exists as monomer, but has the ability to function as monomer or homodimer and interacts with PDILT
  • After translation, ERO1L gets n-glycosylated and the disulfide bonds constitute the redox-active center whereby the Cys-94/Cys-99 disulfide bond accepts an electron from P4HB followed by funneling the same to the active site disulfide Cys-394/Cys-397
  • ERO1L acts by oxidizing directly to P4HB/PDI isomerase through direct disulfide exchange and associates with ERP44
  • ERO1L is implicated in immunoglobulin folding, oxidative stress, release of unfolded cholera toxin from reduced P4HB/PDI upon Vibrio cholerae infection, and plays a key role in ER stress-induced CHOP-dependent apoptosis through inositol 1,4,5-trisphosphate receptor IP3R1 activation.

Compare Similar Items

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Thermo Scientific

PIPA5142731

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Antigen:
ERO1L

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ERO1A

Gene Alias:
Endoplasmic oxidoreductin-1-like protein; endoplasmic reticulum oxidation 1; endoplasmic reticulum oxidoreductase 1 alpha; endoplasmic reticulum oxidoreductase alpha; Endoplasmic reticulum oxidoreductin-1-like protein; ero1; ERO1A; Ero1alpha; ERO1-alpha; ERO1L; ERO1-L; ERO1LA; ERO1-L-alpha; ERO1-like; ERO1-like (S. cerevisiae); ERO1-like protein alpha; Giig11; Global ischemia-induced protein 11; oxidoreductin-1-L-alpha; UNQ434/PRO865

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
30001

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q96HE7

Gene Symbols:
ERO1A

Immunogen:
Peptide with sequence C-QSDEVPDGIKSASY.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

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PIPA5142732

--


Antigen:
UBASH3A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
UBASH3A

Gene Alias:
5830413C03Rik; C330001M22; Cbl-interacting protein 4; CLIP4; STS2; Sts-2; Suppressor of T-cell receptor signaling 2; T-cell ubiquitin ligand 1; T-cell ubiquitin ligand protein; TULA; TULA1; TULA-1; Ubash3a; ubiquitin associated and SH3 domain containing A; ubiquitin associated and SH3 domain containing, A; ubiquitin-associated and SH3 domain-containing protein A

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
53347

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P57075

Gene Symbols:
UBASH3A

Immunogen:
Peptide with sequence C-DSGIRISSVFASP.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

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PIPA5142733

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Antigen:
PTCH

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ptch1

Gene Alias:
A230106A15Rik; BCNS; etID309849.2; FLJ26746; FLJ42602; HGNC:9585; HPE7; lep; leprechaun; mes; mesenchymal dysplasia; NBCCS; OTTHUMP00000021709; OTTHUMP00000021710; patched; Patched 1; patched 2; patched homolog 1; patched homolog 2; patched protein; patched1; patched-2 protein; patched-like protein; protein patched homolog 1; Ptc; ptc1; ptc-1; ptc2; Ptch; PTCH protein +12b; PTCH protein +4'; PTCH protein -10; PTCH protein -3; PTCH protein -3,4,5; PTCH1; Ptch1 protein +12b; PTCH11; Ptch2; RP11-435O5.3

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
19206, 5727

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q13635, Q61115

Gene Symbols:
Ptch1

Immunogen:
Peptide with sequence C-EELKKINYQVDSWEE.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

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PIPA5142734

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Antigen:
PIM2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PIM2

Gene Alias:
DXCch3; PIM2; Pim-2; pim-2 oncogene; Pim-2 proto-oncogene, serine/threonine kinase; pim-2h; proto-oncogene Pim-2 (serine threonine kinase); proviral integration site 2; serine/threonine protein kinase pim-2; serine/threonine-protein kinase pim-2

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
11040

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9P1W9

Gene Symbols:
PIM2

Immunogen:
Peptide with sequence C-KDREAFEAEYRLGP.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid