PIPA5142756
AES Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5142756-Each-of-1 | In Stock | ₹ 38,758.68 |
PIPA5142756 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,758.68
GST (18%): ₹ 6,976.562
Total Price: ₹ 45,735.242
Antigen
AES
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TLE5
Gene Alias
Aes; AES-1; AES-2; AL024115; Amino enhancer of split; amino-terminal enhancer of split; Esp1; gp130-associated protein GAM; Grg; Grg5; Grg-5; Groucho-related protein 5; Protein ESP1; Protein GRG; related to Drosophila groucho; R-esp1; TLE family member 5; TLE family member 5, transcriptional modulator; TLE family member 5; amino-terminal enhancer of split; TLE5
Host Species
Goat
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
166
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.5 mg/mL
Formulation
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q08117
Gene Symbols
AES, TLE5
Immunogen
Peptide with sequence SHLPQQLKFTTSD-C.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Related Products
Description
- Additional Information: This antibody is expected to recognize all reported isoforms (NP_945320.1; NP_001121.2; NP_945321.1)
- This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000
- Adhesion to extracellular matrix regulates cell survival through both integrin engagement and appropriate cell spreading
- Anoikis is the molecular mechanism of apop-tosis induced by integrin detachment
- Amino-terminal enhancer of split (AES) is a member of the Groucho/ transducin-like enhancer of split (TLE) family of transcriptional regulators, a group of transcriptional co-repressors that play important roles in neurogenesis, segmentation, and sex determination
- AES forms a complex with Bit1 (Bcl-2 inhibitor of transcription 1), a mitochondrial protein that is released into the cytoplasm upon onset of apoptosis
- It has been suggested that this complex turns off a survival-promoting gene transcription program controlled by the TLE protein family
- Interestingly, apoptosis of cells transfected with AES and Bit1 could be inhibited if the cells were allowed to attach to fibronectin through the alpha5beta1 integrin suggesting that the Bit1-AES pathway contributing to anoikis is regulated by integrins, and in particular, the alpha5beta1 integrin.
Compare Similar Items
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Antigen: AES
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TLE5
Gene Alias: Aes; AES-1; AES-2; AL024115; Amino enhancer of split; amino-terminal enhancer of split; Esp1; gp130-associated protein GAM; Grg; Grg5; Grg-5; Groucho-related protein 5; Protein ESP1; Protein GRG; related to Drosophila groucho; R-esp1; TLE family member 5; TLE family member 5, transcriptional modulator; TLE family member 5; amino-terminal enhancer of split; TLE5
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 166
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q08117
Gene Symbols: AES, TLE5
Immunogen: Peptide with sequence SHLPQQLKFTTSD-C.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Antigen:
AES
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TLE5
Gene Alias:
Aes; AES-1; AES-2; AL024115; Amino enhancer of split; amino-terminal enhancer of split; Esp1; gp130-associated protein GAM; Grg; Grg5; Grg-5; Groucho-related protein 5; Protein ESP1; Protein GRG; related to Drosophila groucho; R-esp1; TLE family member 5; TLE family member 5, transcriptional modulator; TLE family member 5; amino-terminal enhancer of split; TLE5
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
166
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q08117
Gene Symbols:
AES, TLE5
Immunogen:
Peptide with sequence SHLPQQLKFTTSD-C.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Antigen: Jagged1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: JAG1
Gene Alias: ABE2; AGS; AHD; AWS; CD339; Gsfabe2; HJ1; Htu; JAG1; jagged 1; jagged canonical Notch ligand 1; Jagged1; JAGL1; Ozz; protein jagged-1; Ser-1; Serrate-1
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 16449, 182
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: P78504, Q9QXX0
Gene Symbols: JAG1
Immunogen: Peptide with sequence C-TNKQDNRDLESAQS.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Liquid
Antigen:
Jagged1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
JAG1
Gene Alias:
ABE2; AGS; AHD; AWS; CD339; Gsfabe2; HJ1; Htu; JAG1; jagged 1; jagged canonical Notch ligand 1; Jagged1; JAGL1; Ozz; protein jagged-1; Ser-1; Serrate-1
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
16449, 182
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P78504, Q9QXX0
Gene Symbols:
JAG1
Immunogen:
Peptide with sequence C-TNKQDNRDLESAQS.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Liquid
Antigen: Cannabinoid Receptor 1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CNR1
Gene Alias: brain-type cannabinoid receptor; CANN6; Cannabinoid receptor 1; cannabinoid receptor 1 (brain); CB1; CB1 cannabinoid receptor; CB1 receptor; CB1A; CB1K5; CB1R; CB-R; central cannabinoid receptor; CNR; Cnr1; HGNC:2159; OTTHUMP00000016839; RP1-23D17.1; seven transmembrane domains; G-protein-coupled receptor; Skr6; SKR6R; striatal cannabinoid receptor type 1 protein
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 25248
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: P20272
Gene Symbols: CNR1
Immunogen: Peptide with sequence C-NITEFYNKSLSSFKE.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Rat
Form: Liquid
Antigen:
Cannabinoid Receptor 1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CNR1
Gene Alias:
brain-type cannabinoid receptor; CANN6; Cannabinoid receptor 1; cannabinoid receptor 1 (brain); CB1; CB1 cannabinoid receptor; CB1 receptor; CB1A; CB1K5; CB1R; CB-R; central cannabinoid receptor; CNR; Cnr1; HGNC:2159; OTTHUMP00000016839; RP1-23D17.1; seven transmembrane domains; G-protein-coupled receptor; Skr6; SKR6R; striatal cannabinoid receptor type 1 protein
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
25248
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P20272
Gene Symbols:
CNR1
Immunogen:
Peptide with sequence C-NITEFYNKSLSSFKE.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Rat
Form:
Liquid
Antigen: Cannabinoid Receptor 1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CNR1
Gene Alias: brain-type cannabinoid receptor; CANN6; Cannabinoid receptor 1; cannabinoid receptor 1 (brain); CB1; CB1 cannabinoid receptor; CB1 receptor; CB1A; CB1K5; CB1R; CB-R; central cannabinoid receptor; CNR; Cnr1; HGNC:2159; OTTHUMP00000016839; RP1-23D17.1; seven transmembrane domains; G-protein-coupled receptor; Skr6; SKR6R; striatal cannabinoid receptor type 1 protein
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 1268, 12801
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: P21554, P47746
Gene Symbols: CNR1
Immunogen: Peptide with sequence SNDIQYEDIKGDMAS-C.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Liquid
Antigen:
Cannabinoid Receptor 1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CNR1
Gene Alias:
brain-type cannabinoid receptor; CANN6; Cannabinoid receptor 1; cannabinoid receptor 1 (brain); CB1; CB1 cannabinoid receptor; CB1 receptor; CB1A; CB1K5; CB1R; CB-R; central cannabinoid receptor; CNR; Cnr1; HGNC:2159; OTTHUMP00000016839; RP1-23D17.1; seven transmembrane domains; G-protein-coupled receptor; Skr6; SKR6R; striatal cannabinoid receptor type 1 protein
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
1268, 12801
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P21554, P47746
Gene Symbols:
CNR1
Immunogen:
Peptide with sequence SNDIQYEDIKGDMAS-C.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Liquid