PIPA5142872
SOX9b Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5142872-Each-of-1 | In Stock | ₹ 40,317.00 |
PIPA5142872 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,317.00
GST (18%): ₹ 7,257.06
Total Price: ₹ 47,574.06
Antigen
SOX9b
Classification
Polyclonal
Conjugate
Unconjugated
Host Species
Goat
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Target Species
Human
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
0.5 mg/mL
Formulation
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Immunogen
Peptide with sequence C-PLQDGIDFGAVD.
Quantity
100 μg
Primary or Secondary
Primary
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG
Related Products
Description
- Additional Information: No cross-reactivity with Sox9a
- This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000
- Transcription factor that plays a key role in chondrocytes differentiation and skeletal development
- Specifically binds the 5'-ACAAAG-3' DNA motif present in enhancers and super-enhancers and promotes expression of genes important for chondrogenesis, including COL2A1
- Plays a central role in successive steps of chondrocyte differentiation
- Absolutely required for precartilaginous condensation, the first step in chondrogenesis during which skeletal progenitors differentiate into prechondrocytes
- Together with SOX5 and SOX6, required for overt chondrogenesis when condensed prechondrocytes differentiate into early stage chondrocytes, the second step in chondrogenesis
- Later, required to direct hypertrophic maturation and block osteoblast differentiation of growth plate chondrocytes: maintains chondrocyte columnar proliferation, delays prehypertrophy and then prevents osteoblastic differentiation of chondrocytes
- Also required for chondrocyte hypertrophy, both indirectly, by keeping the lineage fate of chondrocytes, and directly, by remaining present in upper hypertrophic cells
- Low lipid levels are the main nutritional determinant for chondrogenic commitment of skeletal progenitor cells: when lipids levels are low, FOXO transcription factors promote expression of SOX9, which induces chondrogenic commitment and suppresses fatty acid oxidation
- In addition to cartilage development, also acts as a regulator of proliferation and differentiation in epithelial stem/progenitor cells.
Compare Similar Items
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Antigen: SOX9b
Classification: Polyclonal
Conjugate: Unconjugated
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Immunogen: Peptide with sequence C-PLQDGIDFGAVD.
Quantity: 100 μg
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Antigen:
SOX9b
Classification:
Polyclonal
Conjugate:
Unconjugated
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Immunogen:
Peptide with sequence C-PLQDGIDFGAVD.
Quantity:
100 μg
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Antigen: Lava Lamp
Classification: Polyclonal
Conjugate: Unconjugated
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Target Species: Drosophila
Form: Liquid
Applications: Immunocytochemistry
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Immunogen: Peptide with sequence C-HTDAQVSAELAKQ.
Quantity: 100 μg
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Antigen:
Lava Lamp
Classification:
Polyclonal
Conjugate:
Unconjugated
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Target Species:
Drosophila
Form:
Liquid
Applications:
Immunocytochemistry
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Immunogen:
Peptide with sequence C-HTDAQVSAELAKQ.
Quantity:
100 μg
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Antigen: DVL1
Classification: Polyclonal
Conjugate: Unconjugated
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Target Species: Human, Mouse
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Immunogen: Peptide with sequence C-PQLEEAPLTVKSD.
Quantity: 100 μg
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Antigen:
DVL1
Classification:
Polyclonal
Conjugate:
Unconjugated
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Target Species:
Human, Mouse
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Immunogen:
Peptide with sequence C-PQLEEAPLTVKSD.
Quantity:
100 μg
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Antigen: SDCCAG8
Classification: Polyclonal
Conjugate: Unconjugated
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Immunogen: Peptide with sequence C-TINDQSQYIHHLEAE.
Quantity: 100 μg
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Antigen:
SDCCAG8
Classification:
Polyclonal
Conjugate:
Unconjugated
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Immunogen:
Peptide with sequence C-TINDQSQYIHHLEAE.
Quantity:
100 μg
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG