PIPA5143381
Zika Virus NS3 (strain H/PF/2013) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5143381-Each-of-1 | In Stock | ₹ 37,903.08 |
PIPA5143381 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,903.08
GST (18%): ₹ 6,822.554
Total Price: ₹ 44,725.634
Antigen
Zika Virus NS3 (strain H/PF/2013)
Classification
Polyclonal
Conjugate
Unconjugated
Gene Alias
NS3 protease; Zika NS3 protease; Zika Virus NS3 protease
Immunogen
Full length Zika virus NS3 recombinant protein. (Zika virus (strain H/PF/2013))
Quantity
100 μL
Primary or Secondary
Primary
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
0.35 mg/mL
Formulation
PBS with 1% BSA, 20% glycerol and 0.025% Proclin 300; pH 7
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Target Species
Virus
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Store as concentrated solution
- Centrifuge briefly prior to opening vial
- Positive control: Zika-infected Vero
- Zika virus is a flavivirus discovered in 1947, but the association between Zika virus infection and brain disorders was not demonstrated until 2015 in Brazil
- Infection mostly poses a threat to women during pregnancy, since it may cause microcephaly and other neurological dysfunctions in the developing fetus
- ZIKV NS3 expression alone may induce BMP2 maturation, osteogenic gene expression and calcification, but purified NS3 protease has been reported to effectively cleave pro-BMP2 in vitro to generate biologically active mature BMP2
- These findings highlight ZIKV-induced calcification where the NS3 protease subverts the BMP2-mediated osteogenic signalling pathway to trigger brain calcification
- The nonstructural NS3 protein is essential for virus replication because it helps to remodel the cellular microenvironment
- Several reports show that this protease can process cellular substrates and thereby modify cellular pathways that are important for the virus.
Compare Similar Items
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Antigen: Zika Virus NS3 (strain H/PF/2013)
Classification: Polyclonal
Conjugate: Unconjugated
Gene Alias: NS3 protease; Zika NS3 protease; Zika Virus NS3 protease
Immunogen: Full length Zika virus NS3 recombinant protein. (Zika virus (strain H/PF/2013))
Quantity: 100 μL
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.35 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.025% Proclin 300; pH 7
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Target Species: Virus
Product Type: Antibody
Isotype: IgG
Antigen:
Zika Virus NS3 (strain H/PF/2013)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene Alias:
NS3 protease; Zika NS3 protease; Zika Virus NS3 protease
Immunogen:
Full length Zika virus NS3 recombinant protein. (Zika virus (strain H/PF/2013))
Quantity:
100 μL
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.35 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% Proclin 300; pH 7
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Target Species:
Virus
Product Type:
Antibody
Isotype:
IgG
Antigen: Zika Virus NS4B (strain H/PF/2013)
Classification: Polyclonal
Conjugate: Unconjugated
Gene Alias: Zika virus Non-structural protein 4B; Zika virus NS4B; ZIKV Non-structural protein 4B; ZIKV NS4B
Immunogen: Full length Zika virus NS4B recombinant protein. (Zika virus (strain H/PF/2013))
Quantity: 100 μL
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.32 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.025% Proclin 300; pH 7
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Target Species: Virus
Product Type: Antibody
Isotype: IgG
Antigen:
Zika Virus NS4B (strain H/PF/2013)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene Alias:
Zika virus Non-structural protein 4B; Zika virus NS4B; ZIKV Non-structural protein 4B; ZIKV NS4B
Immunogen:
Full length Zika virus NS4B recombinant protein. (Zika virus (strain H/PF/2013))
Quantity:
100 μL
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.32 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% Proclin 300; pH 7
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Target Species:
Virus
Product Type:
Antibody
Isotype:
IgG
Antigen: B-Raf (K601E Mutant)
Classification: Polyclonal
Conjugate: Unconjugated
Gene Alias: B-raf; B-Raf proto-oncogene, serine/threonine kinase; BRAF1; B-RAF1; NS7; RAFB1
Immunogen: Carrier-protein conjugated synthetic peptide surrounding mutant K601E of human B-Raf. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.54 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.025% Proclin 300; pH 7
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
B-Raf (K601E Mutant)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene Alias:
B-raf; B-Raf proto-oncogene, serine/threonine kinase; BRAF1; B-RAF1; NS7; RAFB1
Immunogen:
Carrier-protein conjugated synthetic peptide surrounding mutant K601E of human B-Raf. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.54 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% Proclin 300; pH 7
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: c-Kit (D816V Mutant)
Classification: Polyclonal
Conjugate: Unconjugated
Gene Alias: CD117; C-Kit; KIT proto-oncogene, receptor tyrosine kinase; MASTC; PBT; SCFR
Immunogen: Carrier-protein conjugated synthetic peptide surrounding mutant D816V of human c-Kit. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 0.64 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.025% Proclin 300; pH 7
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
c-Kit (D816V Mutant)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene Alias:
CD117; C-Kit; KIT proto-oncogene, receptor tyrosine kinase; MASTC; PBT; SCFR
Immunogen:
Carrier-protein conjugated synthetic peptide surrounding mutant D816V of human c-Kit. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
0.64 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% Proclin 300; pH 7
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG