PIPA5143393

PAX2a Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5143393-Each-of-1 In Stock ₹ 37,903.08

PIPA5143393 - Each of 1

₹ 37,903.08

In Stock

Quantity

1

Base Price: ₹ 37,903.08

GST (18%): ₹ 6,822.554

Total Price: ₹ 44,725.634

Antigen

PAX2a

Classification

Polyclonal

Conjugate

Unconjugated

Gene Alias

FSGS7; Opdc; optic disc coloboma; paired box 2; paired box gene 2; paired box homeotic gene 2; paired box protein Pax-2; PAPRS; PAX2; Pax-2

Immunogen

Recombinant protein encompassing a sequence within the center region of zebrafish Pax2a. The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (PFA fixed), Western Blot

Concentration

1.03 mg/mL

Formulation

PBS with 20% glycerol and 0.025% Proclin 300; pH 7

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Target Species

Fish, Zebrafish

Product Type

Antibody

Isotype

IgG

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Description

  • Store as concentrated solution
  • Centrifuge briefly prior to opening vial
  • Positive control: 2dpf zebrafish embryos, 36 hpf zebrafish embryos
  • The pax genes are a family of transcription factors that are active in specific tissues during early embryonic development
  • Pax family members possess a DNA-binding domain encoded by the paired box
  • Because paired domain containing genes encode transcription factors, they are capable of executing a genetic program
  • Several pax genes have also been associated with developmental mutations including: pax-3, which is associated with Waardenburg syndrome, pax-6, which is associated with Aniridia, and pax-2, which is associated with Wilms tumor
  • During embryogenesis, Pax-2 is expressed in the developing kidney
  • In particular, the pax-2 gene is expressed in condensing metanephric mesenchyme and in early epithelial structures derived from mesenchyme; however, pax-2 mRNA and protein levels are rapidly down regulated as the tubular epithelium matures
  • Although Pax-2 is down regulated during renal epithelium maturation, Pax-2 expression persists in the undifferentiated epithelium of Wilms' tumors
  • Persistent expression of Pax-2 in Wilms' tumors occurs frequently and correlates with the proliferation of poorly differentiated epithelial cells in these tumors
  • Interestingly, expression of the Wilms' tumor suppresser protein, WT1, coincides with down-regulation of the pax-2 gene; thus, suggesting that WT1 can directly repress pax-2 transcription.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5143393

--


Antigen:
PAX2a

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
FSGS7; Opdc; optic disc coloboma; paired box 2; paired box gene 2; paired box homeotic gene 2; paired box protein Pax-2; PAPRS; PAX2; Pax-2

Immunogen:
Recombinant protein encompassing a sequence within the center region of zebrafish Pax2a. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (PFA fixed), Western Blot

Concentration:
1.03 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% Proclin 300; pH 7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Target Species:
Fish, Zebrafish

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5143394

--


Antigen:
EGR2b

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
AT591; CMT1D; CMT4E; DKFZp686J1957; E3 SUMO-protein ligase EGR2; E3 SUMO-protein transferase ERG2; early growth response 2; early growth response protein 2; Egr2; Egr-2; FLJ1454; FLJ14547; Krox20; Krox-20; Krox-20 homolog; KROX-20, Drosophila, homolog (early growth response-2); NGF1-B; OTTHUMP00000062133; Zfp-25; Zfp-6; Zinc finger protein Krox-20

Immunogen:
Recombinant protein encompassing a sequence within the center region of zebrafish Egr2b. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Target Species:
Zebrafish

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5143399

--


Antigen:
Dharma

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
boz; dha; dharma; nwk

Immunogen:
Recombinant protein encompassing a sequence within the center region of zebrafish Dharma. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Target Species:
Zebrafish

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5143400

--


Antigen:
MAFBa

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
b-maf; c-Maf; kr; Kreisler; Kreisler (maf-related) leucine zipper protein; Kreisler maf-related leucine zipper homolog; Kreisler maf-related leucine zipper homolog (b-maf); KRML; Krml1; LOW QUALITY PROTEIN: transcription factor MafB; maf; MAF bZIP transcription factor B; Maf1; MAFB; maf-B; MAFB/Kreisler basic region/leucine zipper transcription factor; MCTO; MGC43127; segmentation protein Kr; si:ch73-337g9.1; transcription factor Maf; Transcription factor Maf-1; transcription factor MafB; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog b (paralog b); v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B; v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian); V-maf musculoaponeurotic fibrosarcoma oncogene homolog B

Immunogen:
Recombinant protein encompassing a sequence within the center region of zebrafish Mafba. The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (PFA fixed)

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Target Species:
Zebrafish

Product Type:
Antibody

Isotype:
IgG