PIPA5143436

Zika Virus NS3 (strain H/PF/2013) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143436-Each-of-1 In Stock ₹ 37,560.84

PIPA5143436 - Each of 1

₹ 37,560.84

In Stock

Quantity

1

Base Price: ₹ 37,560.84

GST (18%): ₹ 6,760.951

Total Price: ₹ 44,321.791

Antigen

Zika Virus NS3 (strain H/PF/2013)

Classification

Polyclonal

Conjugate

Unconjugated

Gene Alias

NS3 protease; Zika NS3 protease; Zika Virus NS3 protease

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of Zika virus NS3 protein (Zika virus (strain H/PF/2013)). The exact sequence is proprietary.

Quantity

100 μL

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 20% glycerol and 0.025% Proclin 300; pH 7

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Target Species

Virus

Product Type

Antibody

Isotype

IgG

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Description

  • Store as concentrated solution
  • Centrifuge briefly prior to opening vial
  • Zika virus is a flavivirus discovered in 1947, but the association between Zika virus infection and brain disorders was not demonstrated until 2015 in Brazil
  • Infection mostly poses a threat to women during pregnancy, since it may cause microcephaly and other neurological dysfunctions in the developing fetus
  • ZIKV NS3 expression alone may induce BMP2 maturation, osteogenic gene expression and calcification, but purified NS3 protease has been reported to effectively cleave pro-BMP2 in vitro to generate biologically active mature BMP2
  • These findings highlight ZIKV-induced calcification where the NS3 protease subverts the BMP2-mediated osteogenic signalling pathway to trigger brain calcification
  • The nonstructural NS3 protein is essential for virus replication because it helps to remodel the cellular microenvironment
  • Several reports show that this protease can process cellular substrates and thereby modify cellular pathways that are important for the virus.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5143436

--


Antigen:
Zika Virus NS3 (strain H/PF/2013)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
NS3 protease; Zika NS3 protease; Zika Virus NS3 protease

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of Zika virus NS3 protein (Zika virus (strain H/PF/2013)). The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% Proclin 300; pH 7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Target Species:
Virus

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5143437

--


Antigen:
Zika Virus NS4B (strain H/PF/2013)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
Zika virus Non-structural protein 4B; Zika virus NS4B; ZIKV Non-structural protein 4B; ZIKV NS4B

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of Zika virus NS4B protein (Zika virus (strain H/PF/2013)). The exact sequence is proprietary.

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% Proclin 300; pH 7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Target Species:
Virus

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5143438

--


Antigen:
Zika Virus Capsid (strain H/PF/2013)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
Zika virus Capsid; ZIKV Capsid

Immunogen:
Full length Zika virus Capsid recombinant protein. (Zika virus (strain H/PF/2013))

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.74 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% Proclin 300; pH 7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Target Species:
Virus

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5143439

--


Antigen:
Zika Virus NS2B (strain H/PF/2013)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene Alias:
Zika virus Non-structural protein 2B; Zika virus NS2B; ZIKV Non-structural protein 2B; ZIKV NS2B

Immunogen:
Full length Zika virus NS2B recombinant protein. (Zika virus (strain H/PF/2013))

Quantity:
100 μL

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.025% Proclin 300; pH 7

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Target Species:
Virus

Product Type:
Antibody

Isotype:
IgG