PIPA5143720
Phospho-MYH9 (Ser1943) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5143720-Each-of-1 | In Stock | ₹ 44,106.18 |
PIPA5143720 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,106.18
GST (18%): ₹ 7,939.112
Total Price: ₹ 52,045.292
Antigen
Phospho-MYH9 (Ser1943)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MYH9
Gene Alias
BDPLT6; Cellular myosin heavy chain, type A; DFNA17; epsts; fi22c04; fj85e11; flectin; Fltn; FTNS; KLG/PTK7; LOC100911597; LOW QUALITY PROTEIN: myosin-9; MGC104539; MHA; Myh9; myh9.L; myh9a; myh9l2; Myhn1; Myhn-1; myosin; Myosin Heavy Chain 2A; myosin heavy chain 9; myosin heavy chain IX; myosin heavy chain, non-muscle IIa; myosin IIA; myosin, heavy chain 9, non-muscle; myosin, heavy chain 9, non-muscle L homeolog; myosin, heavy chain 9, non-muscle, like-2; myosin, heavy chain 9a, non-muscle; myosin, heavy polypeptide 9, non-muscle; myosin, heavy polypeptide 9a, non-muscle; myosin-2a; myosin9; Myosin-9; myosin-9; myosin-9a; myosin-9-like; NMHC II-A; NMHC-II A; NMHCIIA; NMHC-II-A; NMMHC IIA; NMMHC II-a; nmmhca; NMMHC-A; NMMHC-IIA; non-muscle myosin heavy chain 9; non-muscle myosin heavy chain A; non-muscle myosin heavy chain II A; non-muscle myosin heavy chain IIa; nonmuscle myosin heavy chain II-A; non-muscle myosin heavy polypeptide 9; nonmuscle myosin II heavy chain A; TU72.6; Unknow
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100911597, 17886, 4627
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG
Applications
Immunocytochemistry, Western Blot
Concentration
Lot-Specific
Formulation
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.
P35579, Q62812, Q8VDD5
Gene Symbols
MYH9
Immunogen
Phospho-NMHC-IIA (Ser-1943) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding Ser-1943 in human myosin IIA heavy chain. This peptide sequence is highly conserved in rat and mouse NMHC-IIA, but is not found in NMHC-IIB and is not well conserved in NMHC-IIC.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Liquid
Related Products
Description
- This antibody was cross-adsorbed to unphosphorylated NMHC-IIA (Ser-1943) peptide before affinity purification using phospho-NMHC-IIA (Ser-1943) peptide (without carrier)
- The antibody detects a 200 kDa* protein corresponding to NMHC-IIA on SDS-PAGE immunoblots of human A431, Jurkat, mouse C2C12, and rat PC12 cells
- This reactivity is removed after treatment with lambda phosphatase
- The antibody also detects NMHC-IIA (Ser-1943) phosphorylation in chick Fibroblasts
- TMP21 is a ubiquitously expressed protein that is involved in vesicular targeting and protein transport
- More recent experiments have shown that it is also a component in the presenilin complex and modulates the -gamma-secretase but not the epsilon-secretase cleavage activity of the amyloid precursor protein
- The presenilin complex is composed of the proteins APH1, nicastrin, and PEN2 in addition to presenilin-1
- Together, these proteins cleave the amyloid precursor protein at what is known as the -gamma- and epsilon-sites and can lead to the accumulation of the Abeta cleavage product that is associated with Alzheimer's disease
- Co-immunoprecipitation experiments using antibodies against these proteins also yielded TMP21 indicating that TMP21 may play a role in the regulation of this complex
- Suppression of TMP21 expression by siRNA in transfected cells caused increased -gamma-secretase activity but not epsilon-secretase activity, and increased Abeta production, demonstrating that TMP21 can modulate -gamma-secretase activity.
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Antigen: Phospho-MYH9 (Ser1943)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MYH9
Gene Alias: BDPLT6; Cellular myosin heavy chain, type A; DFNA17; epsts; fi22c04; fj85e11; flectin; Fltn; FTNS; KLG/PTK7; LOC100911597; LOW QUALITY PROTEIN: myosin-9; MGC104539; MHA; Myh9; myh9.L; myh9a; myh9l2; Myhn1; Myhn-1; myosin; Myosin Heavy Chain 2A; myosin heavy chain 9; myosin heavy chain IX; myosin heavy chain, non-muscle IIa; myosin IIA; myosin, heavy chain 9, non-muscle; myosin, heavy chain 9, non-muscle L homeolog; myosin, heavy chain 9, non-muscle, like-2; myosin, heavy chain 9a, non-muscle; myosin, heavy polypeptide 9, non-muscle; myosin, heavy polypeptide 9a, non-muscle; myosin-2a; myosin9; Myosin-9; myosin-9; myosin-9a; myosin-9-like; NMHC II-A; NMHC-II A; NMHCIIA; NMHC-II-A; NMMHC IIA; NMMHC II-a; nmmhca; NMMHC-A; NMMHC-IIA; non-muscle myosin heavy chain 9; non-muscle myosin heavy chain A; non-muscle myosin heavy chain II A; non-muscle myosin heavy chain IIa; nonmuscle myosin heavy chain II-A; non-muscle myosin heavy polypeptide 9; nonmuscle myosin II heavy chain A; TU72.6; Unknow
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100911597, 17886, 4627
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: P35579, Q62812, Q8VDD5
Gene Symbols: MYH9
Immunogen: Phospho-NMHC-IIA (Ser-1943) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding Ser-1943 in human myosin IIA heavy chain. This peptide sequence is highly conserved in rat and mouse NMHC-IIA, but is not found in NMHC-IIB and is not well conserved in NMHC-IIC.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Antigen:
Phospho-MYH9 (Ser1943)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MYH9
Gene Alias:
BDPLT6; Cellular myosin heavy chain, type A; DFNA17; epsts; fi22c04; fj85e11; flectin; Fltn; FTNS; KLG/PTK7; LOC100911597; LOW QUALITY PROTEIN: myosin-9; MGC104539; MHA; Myh9; myh9.L; myh9a; myh9l2; Myhn1; Myhn-1; myosin; Myosin Heavy Chain 2A; myosin heavy chain 9; myosin heavy chain IX; myosin heavy chain, non-muscle IIa; myosin IIA; myosin, heavy chain 9, non-muscle; myosin, heavy chain 9, non-muscle L homeolog; myosin, heavy chain 9, non-muscle, like-2; myosin, heavy chain 9a, non-muscle; myosin, heavy polypeptide 9, non-muscle; myosin, heavy polypeptide 9a, non-muscle; myosin-2a; myosin9; Myosin-9; myosin-9; myosin-9a; myosin-9-like; NMHC II-A; NMHC-II A; NMHCIIA; NMHC-II-A; NMMHC IIA; NMMHC II-a; nmmhca; NMMHC-A; NMMHC-IIA; non-muscle myosin heavy chain 9; non-muscle myosin heavy chain A; non-muscle myosin heavy chain II A; non-muscle myosin heavy chain IIa; nonmuscle myosin heavy chain II-A; non-muscle myosin heavy polypeptide 9; nonmuscle myosin II heavy chain A; TU72.6; Unknow
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100911597, 17886, 4627
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P35579, Q62812, Q8VDD5
Gene Symbols:
MYH9
Immunogen:
Phospho-NMHC-IIA (Ser-1943) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding Ser-1943 in human myosin IIA heavy chain. This peptide sequence is highly conserved in rat and mouse NMHC-IIA, but is not found in NMHC-IIB and is not well conserved in NMHC-IIC.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Antigen: MYH13
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Myh13
Gene Alias: EO Myosin; extraocular muscle myosin heavy chain; extraocular myosin; extraocular myosin heavy chain; fast myosin heavy chain extraocular; MHCEO; MYH13; MyHC; MyHC-EO; MyHC-IIL; Myosin heavy chain 13; Myosin heavy chain, skeletal muscle, extraocular; Myosin heavy chain, skeletal muscle, laryngeal; myosin heavy polypeptide 13; myosin, heavy chain 13, skeletal muscle; myosin, heavy polypeptide 13, skeletal muscle; myosin-13; myosin-13; LOW QUALITY PROTEIN: myosin-13; skeletal muscle myosin heavy chain MyHC-EO/IIL; superfast myosin
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 29605, 544791, 8735
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Applications: Western Blot
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: Q9UKX3
Gene Symbols: Myh13
Immunogen: A synthetic peptide (coupled to KLH) corresponding to amino acid residues in the C-terminal region from mouse MYH13/extraocular myosin. This sequence has 100% identity with rat and human MYH13, and has no homology to other myosin family members.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Antigen:
MYH13
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Myh13
Gene Alias:
EO Myosin; extraocular muscle myosin heavy chain; extraocular myosin; extraocular myosin heavy chain; fast myosin heavy chain extraocular; MHCEO; MYH13; MyHC; MyHC-EO; MyHC-IIL; Myosin heavy chain 13; Myosin heavy chain, skeletal muscle, extraocular; Myosin heavy chain, skeletal muscle, laryngeal; myosin heavy polypeptide 13; myosin, heavy chain 13, skeletal muscle; myosin, heavy polypeptide 13, skeletal muscle; myosin-13; myosin-13; LOW QUALITY PROTEIN: myosin-13; skeletal muscle myosin heavy chain MyHC-EO/IIL; superfast myosin
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
29605, 544791, 8735
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Applications:
Western Blot
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
Q9UKX3
Gene Symbols:
Myh13
Immunogen:
A synthetic peptide (coupled to KLH) corresponding to amino acid residues in the C-terminal region from mouse MYH13/extraocular myosin. This sequence has 100% identity with rat and human MYH13, and has no homology to other myosin family members.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Antigen: MYL9/MYL12
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MYL12A
Gene Alias: 1500001M02Rik; 20 kDa myosin light chain; 2900073G15Rik; AI327049; AI838292; brain specific myosin regulatory light chain; C77744; C80200; Epididymis secretory protein Li 24; HEL-S-24; LC20; MLC2; MLC-2; MLC20; MLC-2A; MLC-2B; MLC-2C; MLCB; MLC-B; MRCL3; MRLC1; Mrlc2; MRLC3; Mrlcb; Myl12a; MYL12B; MYL2B; MYL9; MYLC2B; Mylc2c; myosin light chain 12A; myosin light chain 12B; myosin light chain 9; myosin light chain, regulatory B; myosin light chain, regulatory B-like; myosin light chain, regulatory C; myosin regulatory light chain 1; myosin regulatory light chain 12A; Myosin regulatory light chain 12B; myosin regulatory light chain 2; myosin regulatory light chain 2, nonsarcomeric; Myosin regulatory light chain 2, smooth muscle isoform; myosin regulatory light chain 20 kDa; myosin regulatory light chain 2-A, smooth muscle isoform; Myosin regulatory light chain 2-B, smooth muscle isoform; myosin regulatory light chain 3; myosin regulatory light chain 9; Myosin regulatory light chain MRLC1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 103910, 10398, 10627, 296313, 501203, 50685, 67268, 67938, 98932
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: O14950, P13832, P18666, P19105, P24844, Q3THE2, Q64122, Q9CQ19
Gene Symbols: MYL12A, MYL12B, MYL9
Immunogen: MLC synthetic peptide (coupled to KLH) corresponds to amino acid residues in the N-terminus of human myosin regulatory light chain 12A (Myl12A). This peptide sequence is highly conserved in human, rat, mouse, chicken, and zebrafish Myl12A, and in other smooth muscle and non-muscle MLCs.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Antigen:
MYL9/MYL12
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MYL12A
Gene Alias:
1500001M02Rik; 20 kDa myosin light chain; 2900073G15Rik; AI327049; AI838292; brain specific myosin regulatory light chain; C77744; C80200; Epididymis secretory protein Li 24; HEL-S-24; LC20; MLC2; MLC-2; MLC20; MLC-2A; MLC-2B; MLC-2C; MLCB; MLC-B; MRCL3; MRLC1; Mrlc2; MRLC3; Mrlcb; Myl12a; MYL12B; MYL2B; MYL9; MYLC2B; Mylc2c; myosin light chain 12A; myosin light chain 12B; myosin light chain 9; myosin light chain, regulatory B; myosin light chain, regulatory B-like; myosin light chain, regulatory C; myosin regulatory light chain 1; myosin regulatory light chain 12A; Myosin regulatory light chain 12B; myosin regulatory light chain 2; myosin regulatory light chain 2, nonsarcomeric; Myosin regulatory light chain 2, smooth muscle isoform; myosin regulatory light chain 20 kDa; myosin regulatory light chain 2-A, smooth muscle isoform; Myosin regulatory light chain 2-B, smooth muscle isoform; myosin regulatory light chain 3; myosin regulatory light chain 9; Myosin regulatory light chain MRLC1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
103910, 10398, 10627, 296313, 501203, 50685, 67268, 67938, 98932
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
O14950, P13832, P18666, P19105, P24844, Q3THE2, Q64122, Q9CQ19
Gene Symbols:
MYL12A, MYL12B, MYL9
Immunogen:
MLC synthetic peptide (coupled to KLH) corresponds to amino acid residues in the N-terminus of human myosin regulatory light chain 12A (Myl12A). This peptide sequence is highly conserved in human, rat, mouse, chicken, and zebrafish Myl12A, and in other smooth muscle and non-muscle MLCs.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Antigen: Phospho-MYL12A (Ser1)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Myl12a
Gene Alias: 2900073G15Rik; AI838292; brain specific myosin regulatory light chain; C80200; Epididymis secretory protein Li 24; HEL-S-24; MLC-2; MLC20; MLC-2A; MLC-2B; MLCB; MRCL3; MRLC2; MRLC3; MYL12A; MYL12B; MYL2B; MYLC2B; myosin light chain 12A; myosin light chain, regulatory B-like; myosin regulatory light chain 12A; Myosin regulatory light chain 12B; Myosin regulatory light chain 2, nonsarcomeric; Myosin regulatory light chain 20 kDa; myosin regulatory light chain 2-A, smooth muscle isoform; Myosin regulatory light chain 2-B, smooth muscle isoform; myosin regulatory light chain 3; Myosin regulatory light chain MRLC2; Myosin regulatory light chain MRLC3; myosin regulatory light chain RLC-A; Myosin RLC; myosin RLC-A; myosin, light chain 12A, regulatory, non-sarcomeric; myosin, light polypeptide, regulatory, non-sarcomeric (20kD); NMDA receptor-interacting protein; RGD1309537; RLC; Rlc-a; SHUJUN-1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10627, 501203, 531505, 67268
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: P13832, P19105, Q5E9E2
Gene Symbols: Myl12a
Immunogen: Phospho-MLC (Ser-1) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding Ser-1 in bovine myosin regulatory light chain 9 (Myl9). This peptide sequence is highly conserved in human, rat, and mouse Myl9, and in other smooth muscle and non-muscle MLCs.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Bovine, Human, Mouse, Rat
Form: Liquid
Antigen:
Phospho-MYL12A (Ser1)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Myl12a
Gene Alias:
2900073G15Rik; AI838292; brain specific myosin regulatory light chain; C80200; Epididymis secretory protein Li 24; HEL-S-24; MLC-2; MLC20; MLC-2A; MLC-2B; MLCB; MRCL3; MRLC2; MRLC3; MYL12A; MYL12B; MYL2B; MYLC2B; myosin light chain 12A; myosin light chain, regulatory B-like; myosin regulatory light chain 12A; Myosin regulatory light chain 12B; Myosin regulatory light chain 2, nonsarcomeric; Myosin regulatory light chain 20 kDa; myosin regulatory light chain 2-A, smooth muscle isoform; Myosin regulatory light chain 2-B, smooth muscle isoform; myosin regulatory light chain 3; Myosin regulatory light chain MRLC2; Myosin regulatory light chain MRLC3; myosin regulatory light chain RLC-A; Myosin RLC; myosin RLC-A; myosin, light chain 12A, regulatory, non-sarcomeric; myosin, light polypeptide, regulatory, non-sarcomeric (20kD); NMDA receptor-interacting protein; RGD1309537; RLC; Rlc-a; SHUJUN-1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10627, 501203, 531505, 67268
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P13832, P19105, Q5E9E2
Gene Symbols:
Myl12a
Immunogen:
Phospho-MLC (Ser-1) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding Ser-1 in bovine myosin regulatory light chain 9 (Myl9). This peptide sequence is highly conserved in human, rat, and mouse Myl9, and in other smooth muscle and non-muscle MLCs.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Bovine, Human, Mouse, Rat
Form:
Liquid