PIPA5143857

BUBR1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143857-Each-of-1 In Stock ₹ 34,052.88

PIPA5143857 - Each of 1

₹ 34,052.88

In Stock

Quantity

1

Base Price: ₹ 34,052.88

GST (18%): ₹ 6,129.518

Total Price: ₹ 40,182.398

Antigen

BUBR1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BUB1B

Gene Alias

AU045529; BUB1 budding uninhibited by benzimidazoles 1 homolog beta; BUB1 mitotic checkpoint serine/threonine kinase B; Bub1A; Bub1b; BUB1B, mitotic checkpoint serine/threonine kinase; BUB1beta; BUBR1; budding uninhibited by benzimidazoles 1 beta; budding uninhibited by benzimidazoles 1 homolog beta; budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae); hBub1; hBUBR1; MAD3/BUB1-related protein kinase; MAD3L; Mitotic checkpoint kinase MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MVA1; Protein SSK1; SSK1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12236, 171576, 701

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.

O60566, Q9Z1S0

Gene Symbols

BUB1B

Immunogen

E.coli-derived human BubR1/BUB1B recombinant protein (Position: K26-E448).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Lyophilized

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Description

  • Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL
  • BUBR1 is a member of the Ser/Thr protein kinase family
  • It is a component of the mitotic checkpoint that delays anaphase until all chromosome are properly attached to the mitotic spindle
  • Compromised spindle checkpoints are thought to play an important role in genetic instability that predisposes cells to malignant transformations
  • Human cells contain two related checkpoint protein kinases, evolved from the BUB1 gene; hBUBR1 and hBUB1
  • They are important components of the spindle checkpoint Both kinases monitor mitotic kinetochore-microtubule interactions
  • hBUBR1 is essential for normal mitotic progression as it prevents cells from entering into anaphase too early
  • BUBR1 has been detected in human cancers
  • It has been identified as a novel binding partner of BCSG1 (Breast Cancer-Specific Gene 1), which has been suggested to accelerate the progression of breast cancer by compromising the mitotic checkpoint control through inactivation of BUBR1.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5143857

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Antigen:
BUBR1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BUB1B

Gene Alias:
AU045529; BUB1 budding uninhibited by benzimidazoles 1 homolog beta; BUB1 mitotic checkpoint serine/threonine kinase B; Bub1A; Bub1b; BUB1B, mitotic checkpoint serine/threonine kinase; BUB1beta; BUBR1; budding uninhibited by benzimidazoles 1 beta; budding uninhibited by benzimidazoles 1 homolog beta; budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae); hBub1; hBUBR1; MAD3/BUB1-related protein kinase; MAD3L; Mitotic checkpoint kinase MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MVA1; Protein SSK1; SSK1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12236, 171576, 701

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
O60566, Q9Z1S0

Gene Symbols:
BUB1B

Immunogen:
E.coli-derived human BubR1/BUB1B recombinant protein (Position: K26-E448).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Lyophilized

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PIPA5143858

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Antigen:
NPC2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NPC2

Gene Alias:
2700012J19Rik; AA408070; AU045843; EDDM1; epididymal protein 1; epididymal secretory protein 1; epididymal secretory protein E1; HE1; human epididymis-specific protein 1; mE1; MGC1333; Niemann Pick type C2; niemann Pick type C2 protein homolog; Niemann-Pick disease type C2 protein; Niemann-Pick disease, type C2; Niemann-Pick type C2; NPC intracellular cholesterol transporter 2; Npc2; NP-C2; re1; tissue-specific secretory protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10577, 286898, 67963

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
P61916, Q9Z0J0

Gene Symbols:
NPC2

Immunogen:
E.coli-derived human Niemann Pick C2/NPC2 recombinant protein (Position: E20-L151).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Lyophilized

Img

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PIPA5143859

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Antigen:
HAP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HAP1

Gene Alias:
Hap1; HAP-1; HAP-1 antibody; HAP1-A; HAP1-B; HAP2; hHLP1; HIP5; HLP; HLP1; huntingtin associated protein 1; huntingtin-associated protein 1; huntingtin-associated protein 2; neuroan 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15114, 29430, 9001

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and no preservative

Gene Accession No.:
O35668, P54256, P54257

Gene Symbols:
HAP1

Immunogen:
E.coli-derived human HAP1 recombinant protein (Position: M1-R671).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Lyophilized

Img

Thermo Scientific

PIPA5143860

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Antigen:
PACAP-38

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Adcyap1

Gene Alias:
Adcyap1; adenylate cyclase activating polypeptide 1; adenylate cyclase activating polypeptide 1 (pituitary); PACAP; PACAP-27; PACAP-38; PACAP-related peptide; pituitary adenylate cyclase activating polypeptide; pituitary adenylate cyclase activating polypeptide 1; pituitary adenylate cyclase-activating polypeptide; Pituitary adenylate cyclase-activating polypeptide 27; Pituitary adenylate cyclase-activating polypeptide 38; pituitary adenylate cyclase-activating polypeptide precursor (Pacap); prepro-PACAP; PRP-48

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and no preservative

Gene Accession No.:
P18509

Gene Symbols:
Adcyap1

Immunogen:
A synthetic peptide corresponding to a sequence of human PACAP-38/ADCYAP1 (QMAVKKYLAAVLGKRYKQRVK).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized