PIPA514456

p21 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA514456-Each-of-1 In Stock ₹ 46,929.66

PIPA514456 - Each of 1

₹ 46,929.66

In Stock

Quantity

1

Base Price: ₹ 46,929.66

GST (18%): ₹ 8,447.339

Total Price: ₹ 55,376.999

Antigen

p21

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CDKN1A

Gene Alias

Activating Fragment 1; CAP20; cdk inhibitor CIP1; cdk inhibitor CIP1 (p21); CDKI; CDK-interacting protein 1; CDK-interaction protein 1; Cdkn1; CDKN1A; CDNK1A; CIP1; Cip1); cyclin dependent kinase inhibitor 1A; cyclin-dependent kinase inhibitor 1; cyclin-dependent kinase inhibitor 1A; Cyclin-dependent kinase inhibitor 1A (p21; cyclin-dependent kinase inhibitor 1A (P21); cyclin-dependent kinase inhibitor 1A (p21, Cip1); cyclin-dependent kinase inhibitor 1A variant 1; cyclin-dependent kinase inhibitor 1A variant 2; DNA synthesis inhibitor; MDA6; MDA-6; melanoma differentiation associated protein 6; melanoma differentiation-associated protein; Melanoma differentiation-associated protein 6; OTTHUMP00000016298; p21; p21<WAF1/CIP1>; p21Cip1; p21Cip1/Waf1; p21WAF; PIC1; putative cyclin-dependent kinase inhibitor 1A (p21/WAF1/CIP1); SDI1; SLC12A9; UV96; WAF1; Wild type p53 activated fragment 1 (WAF1); wild-type p53-activated fragment 1

Host Species

Rabbit

Purification Method

Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status

RUO

Gene ID (Entrez)

1026

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

2 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P38936

Gene Symbols

CDKN1A

Immunogen

KLH conjugated synthetic peptide between 134-164 amino acids from the C-terminal region of human p21 (CDKN1A)

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Protein p21 is a tumor suppressor protein which is an inhibitor of Cyclin-dependent kinases (CDK) and is transcriptionally activated by p53
  • P21 is important in the response of cells to genotoxic stress and a major transcriptional target of p53 protein
  • The occurrence of p21 in the nucleus executes binding and inhibition activity of cyclin dependent kinases Cdk1 and Cdk2, and blocks the transition from G1 phase into S phase or from G2 phase into mitosis after DNA damage, which enables the repair of damaged DNA
  • In the cytoplasm, p21 protein has an anti-apoptotic effect
  • P21 is able to bind to and inhibit caspase 3, as well as the apoptotic kinases ASK1 and JNK
  • P21 exhibits a dual function in carcinogenesis, and acts as a tumor suppressor, prevents apoptosis, and acts as an oncogene.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA514456

--


Antigen:
p21

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDKN1A

Gene Alias:
Activating Fragment 1; CAP20; cdk inhibitor CIP1; cdk inhibitor CIP1 (p21); CDKI; CDK-interacting protein 1; CDK-interaction protein 1; Cdkn1; CDKN1A; CDNK1A; CIP1; Cip1); cyclin dependent kinase inhibitor 1A; cyclin-dependent kinase inhibitor 1; cyclin-dependent kinase inhibitor 1A; Cyclin-dependent kinase inhibitor 1A (p21; cyclin-dependent kinase inhibitor 1A (P21); cyclin-dependent kinase inhibitor 1A (p21, Cip1); cyclin-dependent kinase inhibitor 1A variant 1; cyclin-dependent kinase inhibitor 1A variant 2; DNA synthesis inhibitor; MDA6; MDA-6; melanoma differentiation associated protein 6; melanoma differentiation-associated protein; Melanoma differentiation-associated protein 6; OTTHUMP00000016298; p21; p21<WAF1/CIP1>; p21Cip1; p21Cip1/Waf1; p21WAF; PIC1; putative cyclin-dependent kinase inhibitor 1A (p21/WAF1/CIP1); SDI1; SLC12A9; UV96; WAF1; Wild type p53 activated fragment 1 (WAF1); wild-type p53-activated fragment 1

Host Species:
Rabbit

Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status:
RUO

Gene ID (Entrez):
1026

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
2 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P38936

Gene Symbols:
CDKN1A

Immunogen:
KLH conjugated synthetic peptide between 134-164 amino acids from the C-terminal region of human p21 (CDKN1A)

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA514470

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Antigen:
HIPK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HIPK2

Gene Alias:
1110014O20Rik; B230339E18Rik; cb1009; hHIPk2; HIPK2; homeodomain interacting protein kinase 2; homeodomain-interacting protein kinase 2; Nbak1; Nuclear body-associated kinase 1; PRO0593; si:dkey-16j24.2; si:dkey-239k7.1; Sialophorin tail-associated nuclear serine/threonine-protein kinase; Stank; wu:fk56d12

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
28996

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
2 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q9H2X6

Gene Symbols:
HIPK2

Immunogen:
KLH conjugated synthetic peptide between 437-468 amino acids from the N-terminal region of human HIPK2

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
Ig

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Thermo Scientific

PIPA514481

--


Antigen:
PCTAIRE2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDK17

Gene Alias:
6430598J10Rik; CDK17; Cell division protein kinase 17; cyclin dependent kinase 17; cyclin-dependent kinase 17; PCTAIRE protein kinase 2; PCTAIRE2; PCTAIRE-motif protein kinase 2; PCTK2; protein kinase cdc2-related PCTAIRE-2; serine/threonine-protein kinase PCTAIRE-2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5128

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
2 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q00537

Gene Symbols:
CDK17

Immunogen:
KLH conjugated synthetic peptide between 47-77 amino acids from the N-terminal region of human PCTAIRE2 (PCTK2)

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
Ig

Img

Thermo Scientific

PIPA514482

--


Antigen:
PCTAIRE3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cdk18

Gene Alias:
AA682070; Cdk18; Cell division protein kinase 18; Ctk18; cyclin dependent kinase 18; cyclin-dependent kinase 18; PCTAIRE; PCTAIRE protein kinase 3; Pctaire3; PCTAIRE-motif protein kinase 3; Pctk3; Serine/threonine-protein kinase PCTAIRE-3

Host Species:
Rabbit

Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis

Regulatory Status:
RUO

Gene ID (Entrez):
5129

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
2 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q07002

Gene Symbols:
Cdk18

Immunogen:
KLH conjugated synthetic peptide between 25-55 amino acids from the N-terminal region of human PCTAIRE3 (PCTK3)

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG