PIPA514954
RIP2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA514954-Each-of-1 | In Stock | ₹ 44,362.86 |
PIPA514954 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,362.86
GST (18%): ₹ 7,985.315
Total Price: ₹ 52,348.175
Antigen
RIP2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
RIPK2
Gene Alias
2210420D18Rik; CARD3; CARD-carrying kinase; CARD-containing IL-1 beta ICE-kinase; CARD-containing interleukin-1 beta-converting enzyme (ICE)-associated kinase; CARD-containing interleukin-1 beta-converting enzyme-associated kinase; CARDIAK; CCK; D4Bwg0615e; EC 2.7.11.1; GIG30; growth-in; growth-inhibiting gene 30; kinase RIPK2; receptor (TNFRSF)-interacting serine-threonine kinase 2; receptor interacting serine/threonine kinase 2; receptor-interacting protein (RIP)-like interacting caspase-like apoptosis regulatory protein (CLARP) kinase; receptor-interacting protein 2; receptor-interacting serine/threonine-protein kinase 2; receptor-interacting serine-threonine kinase 2; RICK; RIP 2; RIP2; RIP-2; Ripk2; RIP-like; RIP-like-interacting CLARP kinase; Tyrosine-protein kinase RIPK2; UNQ277/PRO314/PRO34092; WUGSC:H_RG437L15.1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography, Protein A
Regulatory Status
RUO
Gene ID (Entrez)
192656, 8767
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
O43353, P58801
Gene Symbols
RIPK2
Immunogen
KLH conjugated synthetic peptide between 458-488 amino acids from the C-terminal region of human RIPK2
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Description
- RIPK2 is a serine/threonine kinase that is involved in cell activation, proliferation, differentiation, and apoptosis
- Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains
- Contributes to the tyrosine phosphorylation of the guanine exchange factor ARHGEF2 through Src tyrosine kinase leading to NF-kappaB activation by NOD2
- Once recruited, RIPK2 autophosphorylates and undergoes 'Lys-63'-linked polyubiquitination by E3 ubiquitin ligases XIAP, BIRC2 and BIRC3
- The polyubiquitinated protein mediates the recruitment of MAP3K7/TAK1 to IKBKG/NEMO and induces 'Lys-63'-linked polyubiquitination of IKBKG/NEMO and subsequent activation of IKBKB/IKKB
- In turn, NF-kappa-B is released from NF-kappa-B inhibitors and translocates into the nucleus where it activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis
- Plays also a role during engagement of the T-cell receptor (TCR) in promoting BCL10 phosphorylation and subsequent NF-kappa-B activation.
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Antigen: RIP2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RIPK2
Gene Alias: 2210420D18Rik; CARD3; CARD-carrying kinase; CARD-containing IL-1 beta ICE-kinase; CARD-containing interleukin-1 beta-converting enzyme (ICE)-associated kinase; CARD-containing interleukin-1 beta-converting enzyme-associated kinase; CARDIAK; CCK; D4Bwg0615e; EC 2.7.11.1; GIG30; growth-in; growth-inhibiting gene 30; kinase RIPK2; receptor (TNFRSF)-interacting serine-threonine kinase 2; receptor interacting serine/threonine kinase 2; receptor-interacting protein (RIP)-like interacting caspase-like apoptosis regulatory protein (CLARP) kinase; receptor-interacting protein 2; receptor-interacting serine/threonine-protein kinase 2; receptor-interacting serine-threonine kinase 2; RICK; RIP 2; RIP2; RIP-2; Ripk2; RIP-like; RIP-like-interacting CLARP kinase; Tyrosine-protein kinase RIPK2; UNQ277/PRO314/PRO34092; WUGSC:H_RG437L15.1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography, Protein A
Regulatory Status: RUO
Gene ID (Entrez): 192656, 8767
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: O43353, P58801
Gene Symbols: RIPK2
Immunogen: KLH conjugated synthetic peptide between 458-488 amino acids from the C-terminal region of human RIPK2
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
RIP2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RIPK2
Gene Alias:
2210420D18Rik; CARD3; CARD-carrying kinase; CARD-containing IL-1 beta ICE-kinase; CARD-containing interleukin-1 beta-converting enzyme (ICE)-associated kinase; CARD-containing interleukin-1 beta-converting enzyme-associated kinase; CARDIAK; CCK; D4Bwg0615e; EC 2.7.11.1; GIG30; growth-in; growth-inhibiting gene 30; kinase RIPK2; receptor (TNFRSF)-interacting serine-threonine kinase 2; receptor interacting serine/threonine kinase 2; receptor-interacting protein (RIP)-like interacting caspase-like apoptosis regulatory protein (CLARP) kinase; receptor-interacting protein 2; receptor-interacting serine/threonine-protein kinase 2; receptor-interacting serine-threonine kinase 2; RICK; RIP 2; RIP2; RIP-2; Ripk2; RIP-like; RIP-like-interacting CLARP kinase; Tyrosine-protein kinase RIPK2; UNQ277/PRO314/PRO34092; WUGSC:H_RG437L15.1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography, Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
192656, 8767
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
O43353, P58801
Gene Symbols:
RIPK2
Immunogen:
KLH conjugated synthetic peptide between 458-488 amino acids from the C-terminal region of human RIPK2
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: RIP3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RIPK3
Gene Alias: 2610528K09Rik; AW107945; Hcyp2; Homocysteine respondent protein HCYP2; mRIP3; receptor interacting protein 3; receptor interacting serine/threonine kinase 3; receptor-interacting protein 3; receptor-interacting serine/threonine-protein kinase 3; receptor-interacting serine-threonine kinase 3; Rip3; RIP-3; Ripk3; RIP-like protein kinase 3
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status: RUO
Gene ID (Entrez): 11035, 56532
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 2 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q9QZL0, Q9Y572
Gene Symbols: RIPK3
Immunogen: KLH conjugated synthetic peptide between 489-518 amino acids from the C-terminal region of human RIPK3
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
RIP3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RIPK3
Gene Alias:
2610528K09Rik; AW107945; Hcyp2; Homocysteine respondent protein HCYP2; mRIP3; receptor interacting protein 3; receptor interacting serine/threonine kinase 3; receptor-interacting protein 3; receptor-interacting serine/threonine-protein kinase 3; receptor-interacting serine-threonine kinase 3; Rip3; RIP-3; Ripk3; RIP-like protein kinase 3
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status:
RUO
Gene ID (Entrez):
11035, 56532
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
2 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
Q9QZL0, Q9Y572
Gene Symbols:
RIPK3
Immunogen:
KLH conjugated synthetic peptide between 489-518 amino acids from the C-terminal region of human RIPK3
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: TGFBR1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TGFBR1
Gene Alias: AAT5; activin A receptor type II-like kinase, 53kDa; activin A receptor type II-like protein kinase of 53kD; Activin receptor-like kinase 5; ACVRLK4; ALK5; Alk-5; AU017191; ESK2; ESS1; LDS1; LDS1A; LDS2A; MSSE; mutant transforming growth factor beta receptor I; ser; serine/threonine-protein kinase receptor R4; SKR4; TbetaRI; tbetaR-I; tgf beta receptor 1; TGF-beta receptor type I; TGF-beta receptor type-1; TGF-beta type I receptor; TGFBR1; TGFR1; TGFR-1; Transfor; transforming growth factor beta receptor 1; transforming growth factor beta receptor I; transforming growth factor, beta receptor 1; transforming growth factor, beta receptor I; transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa); transforming growth factor-beta receptor type I
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 7046
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 2 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P36897
Gene Symbols: TGFBR1
Immunogen: KLH conjugated synthetic peptide between 134-163 amino acids from the central region of human TGF Beta Receptor I
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: Ig
Antigen:
TGFBR1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TGFBR1
Gene Alias:
AAT5; activin A receptor type II-like kinase, 53kDa; activin A receptor type II-like protein kinase of 53kD; Activin receptor-like kinase 5; ACVRLK4; ALK5; Alk-5; AU017191; ESK2; ESS1; LDS1; LDS1A; LDS2A; MSSE; mutant transforming growth factor beta receptor I; ser; serine/threonine-protein kinase receptor R4; SKR4; TbetaRI; tbetaR-I; tgf beta receptor 1; TGF-beta receptor type I; TGF-beta receptor type-1; TGF-beta type I receptor; TGFBR1; TGFR1; TGFR-1; Transfor; transforming growth factor beta receptor 1; transforming growth factor beta receptor I; transforming growth factor, beta receptor 1; transforming growth factor, beta receptor I; transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa); transforming growth factor-beta receptor type I
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
7046
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
2 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P36897
Gene Symbols:
TGFBR1
Immunogen:
KLH conjugated synthetic peptide between 134-163 amino acids from the central region of human TGF Beta Receptor I
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
Ig
Antigen: TGM2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TGM2
Gene Alias: C polypeptide; C polypeptide, protein-glutamine-gamma-glutamyltransferase; G alpha h; G[a]h; G-ALPHA-h; GNAH; Protein-glutamine gamma-glutamyltransferase 2; protein-glutamine-gamma-glutamyltransferase; RP5-1054A22.2; TG C; TG(C); TG2; TGase C; TGase H; TGase2; TGase-2; TGase-H; TgaseII; TGC; TGM2; Tissue transglutaminase; Tissue type transglutaminase; tissue-type transglutaminase; transglutaminase; transglutaminase 2; transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase); Transglutaminase 2 C polypeptide; transglutaminase 2, C polypeptide; transglutaminase C; Transglutaminase H; transglutaminase-2; tTG; tTGas
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status: RUO
Gene ID (Entrez): 7052
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 2 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P21980
Gene Symbols: TGM2
Immunogen: KLH conjugated synthetic peptide between 429-458 amino acids from the central region of human Transglutaminase (TGM2)
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TGM2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TGM2
Gene Alias:
C polypeptide; C polypeptide, protein-glutamine-gamma-glutamyltransferase; G alpha h; G[a]h; G-ALPHA-h; GNAH; Protein-glutamine gamma-glutamyltransferase 2; protein-glutamine-gamma-glutamyltransferase; RP5-1054A22.2; TG C; TG(C); TG2; TGase C; TGase H; TGase2; TGase-2; TGase-H; TgaseII; TGC; TGM2; Tissue transglutaminase; Tissue type transglutaminase; tissue-type transglutaminase; transglutaminase; transglutaminase 2; transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase); Transglutaminase 2 C polypeptide; transglutaminase 2, C polypeptide; transglutaminase C; Transglutaminase H; transglutaminase-2; tTG; tTGas
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status:
RUO
Gene ID (Entrez):
7052
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
2 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P21980
Gene Symbols:
TGM2
Immunogen:
KLH conjugated synthetic peptide between 429-458 amino acids from the central region of human Transglutaminase (TGM2)
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG