PIPA515028
MERTK Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA515028-Each-of-1 | In Stock | ₹ 47,443.02 |
PIPA515028 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,443.02
GST (18%): ₹ 8,539.744
Total Price: ₹ 55,982.764
Antigen
MERTK
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Mertk
Gene Alias
c-Eyk; c-mer; c-mer proto-oncogene tyrosine kinase; Eyk; MER; MER proto-oncogene, tyrosine kinase; MER receptor tyrosine kinase; MERTK; MGC133349; nmf12; Nyk; Proto-oncogene c-Mer; proto-oncogene tyrosine-protein kinase MER; rdy; receptor tyrosine kinase MerTK; Receptor tyrosine tinase gene probably the gene for Rdy; retinal dystrophy; RP38; sMER; sMERTK; soluble MER; soluble MERTK; STK kinase; Tyro 12; Tyro12; Tyrosine-protein kinase Mer
Host Species
Rabbit
Purification Method
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status
RUO
Gene ID (Entrez)
10461, 17289, 65037
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
2 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P57097, Q12866, Q60805
Gene Symbols
Mertk
Immunogen
His tag recombinant protein (45-382aa) of human MERTK
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Description
- MERTK (cMER) is a tyrosine kinase proto-oncogene and is involved in the retinal pigment epithelium (RPE) phagocytosis pathway, which is implicated in human retinal disease
- Regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis)
- Ligand binding at the cell surface induces autophosphorylation of MERTK on its intracellular domain that provides docking sites for downstream signaling molecules
- Following activation by ligand, interacts with GRB2 or PLCG2 and induces phosphorylation of MAPK1, MAPK2, FAK/PTK2 or RAC1
- MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment
- Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis
- Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.
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Antigen: MERTK
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Mertk
Gene Alias: c-Eyk; c-mer; c-mer proto-oncogene tyrosine kinase; Eyk; MER; MER proto-oncogene, tyrosine kinase; MER receptor tyrosine kinase; MERTK; MGC133349; nmf12; Nyk; Proto-oncogene c-Mer; proto-oncogene tyrosine-protein kinase MER; rdy; receptor tyrosine kinase MerTK; Receptor tyrosine tinase gene probably the gene for Rdy; retinal dystrophy; RP38; sMER; sMERTK; soluble MER; soluble MERTK; STK kinase; Tyro 12; Tyro12; Tyrosine-protein kinase Mer
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status: RUO
Gene ID (Entrez): 10461, 17289, 65037
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 2 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P57097, Q12866, Q60805
Gene Symbols: Mertk
Immunogen: His tag recombinant protein (45-382aa) of human MERTK
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MERTK
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Mertk
Gene Alias:
c-Eyk; c-mer; c-mer proto-oncogene tyrosine kinase; Eyk; MER; MER proto-oncogene, tyrosine kinase; MER receptor tyrosine kinase; MERTK; MGC133349; nmf12; Nyk; Proto-oncogene c-Mer; proto-oncogene tyrosine-protein kinase MER; rdy; receptor tyrosine kinase MerTK; Receptor tyrosine tinase gene probably the gene for Rdy; retinal dystrophy; RP38; sMER; sMERTK; soluble MER; soluble MERTK; STK kinase; Tyro 12; Tyro12; Tyrosine-protein kinase Mer
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status:
RUO
Gene ID (Entrez):
10461, 17289, 65037
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
2 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P57097, Q12866, Q60805
Gene Symbols:
Mertk
Immunogen:
His tag recombinant protein (45-382aa) of human MERTK
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: AMPD3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ampd3
Gene Alias: adenosine monophosphate deaminase (isoform E); adenosine monophosphate deaminase 3; AMP aminohydrolase; AMP deaminase 3; AMP deaminase H-type; AMP deaminase isoform E; Ampd; Ampd3; Erythrocyte AMP deaminase; erythrocyte type AMP deaminase; erythrocyte-specific AMP deaminase; heart-type AMPD; myoadenylate deaminase
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11717, 272
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: __
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: O08739, Q01432
Gene Symbols: Ampd3
Immunogen: KLH conjugated synthetic peptide between 325-356 amino acids from the central region of human AMPD3
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
AMPD3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ampd3
Gene Alias:
adenosine monophosphate deaminase (isoform E); adenosine monophosphate deaminase 3; AMP aminohydrolase; AMP deaminase 3; AMP deaminase H-type; AMP deaminase isoform E; Ampd; Ampd3; Erythrocyte AMP deaminase; erythrocyte type AMP deaminase; erythrocyte-specific AMP deaminase; heart-type AMPD; myoadenylate deaminase
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11717, 272
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
__
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
O08739, Q01432
Gene Symbols:
Ampd3
Immunogen:
KLH conjugated synthetic peptide between 325-356 amino acids from the central region of human AMPD3
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: CYP4Z1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CYP4Z1
Gene Alias: CYP4A20; CYP4Z1; CYPIVZ1; cytochrome P450 4Z1; cytochrome P450 family 4 subfamily Z member 1; cytochrome P450, family 4, subfamily Z, polypeptide 1; UNQ3060/PRO9882
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status: RUO
Gene ID (Entrez): 199974
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 2 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q86W10
Gene Symbols: CYP4Z1
Immunogen: KLH conjugated synthetic peptide between 89-118 amino acids from the N-terminal region of human CYP4Z1
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CYP4Z1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CYP4Z1
Gene Alias:
CYP4A20; CYP4Z1; CYPIVZ1; cytochrome P450 4Z1; cytochrome P450 family 4 subfamily Z member 1; cytochrome P450, family 4, subfamily Z, polypeptide 1; UNQ3060/PRO9882
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status:
RUO
Gene ID (Entrez):
199974
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
2 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
Q86W10
Gene Symbols:
CYP4Z1
Immunogen:
KLH conjugated synthetic peptide between 89-118 amino acids from the N-terminal region of human CYP4Z1
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ALOX15
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Alox15
Gene Alias: 12/15-lipoxygenase; 12/15-LO; 12/15-LOX; 12-LO; 12-LOX; 15-lipooxygenase-1; 15-LOX; 15-LOX-1; 15LOX-1; 15-LOX2; Alox12; Alox12l; Alox15; Arachidonate 12-lipoxygenase, leukocyte-type; arachidonate 15-lipoxygenase; Arachidonate omega-6 lipoxygenase; L-12LO; LOG15
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status: RUO
Gene ID (Entrez): 246
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P16050
Gene Symbols: Alox15
Immunogen: KLH conjugated synthetic peptide between 610-643 amino acids from the C-terminal region of human ALOX15
Quantity: 200 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ALOX15
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Alox15
Gene Alias:
12/15-lipoxygenase; 12/15-LO; 12/15-LOX; 12-LO; 12-LOX; 15-lipooxygenase-1; 15-LOX; 15-LOX-1; 15LOX-1; 15-LOX2; Alox12; Alox12l; Alox15; Arachidonate 12-lipoxygenase, leukocyte-type; arachidonate 15-lipoxygenase; Arachidonate omega-6 lipoxygenase; L-12LO; LOG15
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status:
RUO
Gene ID (Entrez):
246
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P16050
Gene Symbols:
Alox15
Immunogen:
KLH conjugated synthetic peptide between 610-643 amino acids from the C-terminal region of human ALOX15
Quantity:
200 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG