PIPA515328
ARK5 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA515328-Each-of-1 | In Stock | ₹ 44,790.66 |
PIPA515328 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,790.66
GST (18%): ₹ 8,062.319
Total Price: ₹ 52,852.979
Antigen
ARK5
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NUAK1
Gene Alias
AMP-activated protein kinase family member 5; AMPK-related protein kinase 5; ARK5; AU014801; AW494241; B230104P22Rik; I79_017442; KIAA0537; NUAK family kinase 1; NUAK family SNF1-like kinase 1; NUAK family, SNF1-like kinase, 1; Nuak1; Omphalocele kinase 1; Omphk1; RGD1309956; ZNUAK family, SNF1-like kinase, 1
Host Species
Rabbit
Purification Method
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status
RUO
Gene ID (Entrez)
77976, 9891
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
2 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
O60285, Q641K5
Gene Symbols
NUAK1
Immunogen
KLH conjugated synthetic peptide between 604-634 amino acids from the C-terminal region of human ARK5
Quantity
200 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Description
- NUAK1 (ARK5) is a serine/threonine kinase that plays a role in many cellular functions
- The overexpression of this kinase has been associated with tumor invasion and metastasis (colorectal neoplasm)
- Acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of 'Ser-464' of LATS1, thereby controlling its stability
- Controls cell adhesion by regulating activity of the myosin protein phosphatase 1 (PP1) complex
- Acts by mediating phosphorylation of PPP1R12A subunit of myosin PP1: phosphorylated PPP1R12A then interacts with 14-3-3, leading to reduced dephosphorylation of myosin MLC2 by myosin PP1
- May be involved in DNA damage response: phosphorylates p53/TP53 at 'Ser-15' and 'Ser-392' and is recruited to the CDKN1A/WAF1 promoter to participate in transcription activation by p53/TP53
- May also act as a tumor malignancy-associated factor by promoting tumor invasion and metastasis under regulation and phosphorylation by AKT1
- Suppresses Fas-induced apoptosis by mediating phosphorylation of CASP6, thereby suppressing the activation of the caspase and the subsequent cleavage of CFLAR
- Regulates UV radiation-induced DNA damage response mediated by CDKN1A
- In association with STK11, phosphorylates CDKN1A in response to UV radiation and contributes to its degradation which is necessary for optimal DNA repair.
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Antigen: ARK5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NUAK1
Gene Alias: AMP-activated protein kinase family member 5; AMPK-related protein kinase 5; ARK5; AU014801; AW494241; B230104P22Rik; I79_017442; KIAA0537; NUAK family kinase 1; NUAK family SNF1-like kinase 1; NUAK family, SNF1-like kinase, 1; Nuak1; Omphalocele kinase 1; Omphk1; RGD1309956; ZNUAK family, SNF1-like kinase, 1
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status: RUO
Gene ID (Entrez): 77976, 9891
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 2 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: O60285, Q641K5
Gene Symbols: NUAK1
Immunogen: KLH conjugated synthetic peptide between 604-634 amino acids from the C-terminal region of human ARK5
Quantity: 200 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
ARK5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NUAK1
Gene Alias:
AMP-activated protein kinase family member 5; AMPK-related protein kinase 5; ARK5; AU014801; AW494241; B230104P22Rik; I79_017442; KIAA0537; NUAK family kinase 1; NUAK family SNF1-like kinase 1; NUAK family, SNF1-like kinase, 1; Nuak1; Omphalocele kinase 1; Omphk1; RGD1309956; ZNUAK family, SNF1-like kinase, 1
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status:
RUO
Gene ID (Entrez):
77976, 9891
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
2 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
O60285, Q641K5
Gene Symbols:
NUAK1
Immunogen:
KLH conjugated synthetic peptide between 604-634 amino acids from the C-terminal region of human ARK5
Quantity:
200 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: MOS
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MOS
Gene Alias: C-MOS; c-mos oncogene; c-mos proto-oncogene; MGC119962; MGC119963; Moloney sarcoma oncogene; mos; MOS proto-oncogene, serine/threonine kinase; MOS proto-oncogene, serine/threonine kinase L homeolog; mos.L; mosxe; MSV; oncogene MOS, Moloney murine sarcoma virus; oocyte maturation factor mos; p39; p39-mos; pp39-mos; protein kinase; proto-oncogene c-Mos; Proto-oncogene serine/threonine-protein kinase mos; serine/threonine-protein kinase mos; v-mos Moloney murine sarcoma viral oncogene homolog; v-mos Moloney murine sarcoma viral oncogene homolog L homeolog; XELAEV_18032032mg
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status: RUO
Gene ID (Entrez): 4342
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: __
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P00540
Gene Symbols: MOS
Immunogen: KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MOS
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MOS
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MOS
Gene Alias:
C-MOS; c-mos oncogene; c-mos proto-oncogene; MGC119962; MGC119963; Moloney sarcoma oncogene; mos; MOS proto-oncogene, serine/threonine kinase; MOS proto-oncogene, serine/threonine kinase L homeolog; mos.L; mosxe; MSV; oncogene MOS, Moloney murine sarcoma virus; oocyte maturation factor mos; p39; p39-mos; pp39-mos; protein kinase; proto-oncogene c-Mos; Proto-oncogene serine/threonine-protein kinase mos; serine/threonine-protein kinase mos; v-mos Moloney murine sarcoma viral oncogene homolog; v-mos Moloney murine sarcoma viral oncogene homolog L homeolog; XELAEV_18032032mg
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status:
RUO
Gene ID (Entrez):
4342
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
__
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P00540
Gene Symbols:
MOS
Immunogen:
KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MOS
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: NEK2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NEK2
Gene Alias: AA617254; C77054; HSPK 21; HsPK21; NEK 2; NEK 2A; Nek2; Nek2 kinase; NEK2A; Never in mitosis A-related kinase 2; NIMA - related expressed kinase 2; NIMA (never in mitosis gene a)-related expressed kinase 2; NIMA (never in mitosis gene a)-related kinase 2; NIMA related kinase 2; nimA-like protein kinase 1; NIMA-related expressed kinase 2; NIMA-related kinase 2; nimA-related protein kinase 2; NLK 1; NLK1; PPP1R111; protein phosphatase 1, regulatory subunit 111; RP67; Serine/threonine-protein kinase Nek2
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status: RUO
Gene ID (Entrez): 4751
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P51955
Gene Symbols: NEK2
Immunogen: KLH conjugated synthetic peptide between 350-382 amino acids from the central region of human NEK2
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NEK2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NEK2
Gene Alias:
AA617254; C77054; HSPK 21; HsPK21; NEK 2; NEK 2A; Nek2; Nek2 kinase; NEK2A; Never in mitosis A-related kinase 2; NIMA - related expressed kinase 2; NIMA (never in mitosis gene a)-related expressed kinase 2; NIMA (never in mitosis gene a)-related kinase 2; NIMA related kinase 2; nimA-like protein kinase 1; NIMA-related expressed kinase 2; NIMA-related kinase 2; nimA-related protein kinase 2; NLK 1; NLK1; PPP1R111; protein phosphatase 1, regulatory subunit 111; RP67; Serine/threonine-protein kinase Nek2
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status:
RUO
Gene ID (Entrez):
4751
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P51955
Gene Symbols:
NEK2
Immunogen:
KLH conjugated synthetic peptide between 350-382 amino acids from the central region of human NEK2
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PCK1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PCK1
Gene Alias: AI265463; GTP; HGNC:8724; MGC22652; PCK; Pck1; Pck-1; PE PEPCKC; PEP carboxykinase; PEPCK; PEPCK1; PEPCKC; PEPCK-C; phosphoenolpyruvate carboxykinase (GTP); phosphoenolpyruvate carboxykinase 1; phosphoenolpyruvate carboxykinase 1 (soluble); phosphoenolpyruvate carboxykinase 1, cytosolic; phosphoenolpyruvate carboxykinase, cytosolic; phosphoenolpyruvate carboxykinase, cytosolic (GTP); phosphoenolpyruvate carboxykinase, cytosolic [GTP]; phosphoenolpyruvate carboxylase; phosphopyruvate carboxylase; RATPEPCK
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status: RUO
Gene ID (Entrez): 18534, 5105
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 2.0 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P35558, Q9Z2V4
Gene Symbols: PCK1
Immunogen: KLH conjugated synthetic peptide between 40-70 amino acids from the N-terminal region of human PCK1
Quantity: 400 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
PCK1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PCK1
Gene Alias:
AI265463; GTP; HGNC:8724; MGC22652; PCK; Pck1; Pck-1; PE PEPCKC; PEP carboxykinase; PEPCK; PEPCK1; PEPCKC; PEPCK-C; phosphoenolpyruvate carboxykinase (GTP); phosphoenolpyruvate carboxykinase 1; phosphoenolpyruvate carboxykinase 1 (soluble); phosphoenolpyruvate carboxykinase 1, cytosolic; phosphoenolpyruvate carboxykinase, cytosolic; phosphoenolpyruvate carboxykinase, cytosolic (GTP); phosphoenolpyruvate carboxykinase, cytosolic [GTP]; phosphoenolpyruvate carboxylase; phosphopyruvate carboxylase; RATPEPCK
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status:
RUO
Gene ID (Entrez):
18534, 5105
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
2.0 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P35558, Q9Z2V4
Gene Symbols:
PCK1
Immunogen:
KLH conjugated synthetic peptide between 40-70 amino acids from the N-terminal region of human PCK1
Quantity:
400 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG