PIPA516529

CXCR4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA516529-Each-of-1 In Stock ₹ 45,304.02

PIPA516529 - Each of 1

₹ 45,304.02

In Stock

Quantity

1

Base Price: ₹ 45,304.02

GST (18%): ₹ 8,154.724

Total Price: ₹ 53,458.744

Antigen

CXCR4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Cxcr4

Gene Alias

b2b220Clo; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD antigen CD184; CD184; CD184 antigen; chemokine (C-X-C motif) receptor 4; chemokine (C-X-C) receptor 4; chemokine receptor; chemokine receptor (LCR1); chemokine receptor 4; chemokine receptor CXCR4; Cmkar4; CXC; CXC chemokine receptor; C-X-C chemokine receptor type 4; CXC motif chemokine; C-X-C motif chemokine receptor 4; CXCR4; CXC-R4; CXCR-4; D2S201E; FB22; Fusin; HM89; HSY3RR; HUMSTR; LAP3; LAP-3; LCR1; LESTR; Leukocyte-derived seven transmembrane domain receptor; leukocyte-expressed seven-transmembrane-domain; lipopolysaccharide-associated protein 3; LPS-associated protein 3; neuropeptide Y receptor Y3; neuropeptide Y3 receptor; NPY3R; NPYR; NPYRL; NPYY3R; PB-CKR; PBSF/SDF-1; pre-B-cell-derived chemokine receptor; SDF-1 receptor; Sdf1r; seven transmembrane helix receptor; seven-transmembrane-segment receptor, spleen; stromal cell-derived factor 1 receptor; WHIM; WHIMS

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

12767, 7852

Content And Storage

4° C

Form

Liquid

Applications

Flow Cytometry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.

P61073, P70658

Gene Symbols

Cxcr4

Immunogen

A synthetic peptide derived from the second extracellular loop of human CXCR4

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate

Product Type

Antibody

Isotype

IgG

Description

  • PA5-16529 targets CXCR4 in FACS and WB applications and shows reactivity with mouse, Non-human primate, and Human samples
  • The PA5-16529 immunogen is a synthetic peptide derived from the second extracellular loop of human CXCR4
  • CXCR4 (Fusin, LESTR, HUMSTR) is a member of the G-protein-coupled chemokine receptor family with seven membrane-spanning domains, and functions as a co-receptor for X4 HIV-1 entry into CD4+ cells
  • CXCR4 has been proved to be the co-receptor for HIV-2's binding to CD4 through envelope glycoprotein gp 120 and promotes Env-mediated fusion of the virus
  • In other cases, CXCR4 can even function as the only receptor for HIV-2's binding to the CD4 host cells
  • CXCR4 is the receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation
  • CXCR4 acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels
  • Also, CXCR4 is involved in hematopoiesis and in cardiac ventricular septum formation, and plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells
  • In the CNS, CXCR4 could mediate hippocampal-neuron survival and is involved in cerebellar development
  • CXCR4 binds bacterial lipopolysaccharide (LPS) and mediates LPS-induced inflammatory response, including TNF secretion by monocytes
  • Antibodies to CXCR4 block HIV-1 and HIV-2 fusion and infection of human target cells
  • The amino-terminal domain and the second extracellular loop of CXCR4 serve as HIV biding sites.

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Thermo Scientific

PIPA516529

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Antigen:
CXCR4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cxcr4

Gene Alias:
b2b220Clo; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD antigen CD184; CD184; CD184 antigen; chemokine (C-X-C motif) receptor 4; chemokine (C-X-C) receptor 4; chemokine receptor; chemokine receptor (LCR1); chemokine receptor 4; chemokine receptor CXCR4; Cmkar4; CXC; CXC chemokine receptor; C-X-C chemokine receptor type 4; CXC motif chemokine; C-X-C motif chemokine receptor 4; CXCR4; CXC-R4; CXCR-4; D2S201E; FB22; Fusin; HM89; HSY3RR; HUMSTR; LAP3; LAP-3; LCR1; LESTR; Leukocyte-derived seven transmembrane domain receptor; leukocyte-expressed seven-transmembrane-domain; lipopolysaccharide-associated protein 3; LPS-associated protein 3; neuropeptide Y receptor Y3; neuropeptide Y3 receptor; NPY3R; NPYR; NPYRL; NPYY3R; PB-CKR; PBSF/SDF-1; pre-B-cell-derived chemokine receptor; SDF-1 receptor; Sdf1r; seven transmembrane helix receptor; seven-transmembrane-segment receptor, spleen; stromal cell-derived factor 1 receptor; WHIM; WHIMS

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12767, 7852

Content And Storage:
4° C

Form:
Liquid

Applications:
Flow Cytometry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P61073, P70658

Gene Symbols:
Cxcr4

Immunogen:
A synthetic peptide derived from the second extracellular loop of human CXCR4

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA516576

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Antigen:
PDGFRB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pdgfrb

Gene Alias:
AI528809; Beta platelet-derived growth factor receptor; beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; CD140B; CD140b antigen; IBGC4; IMF1; JTK12; KOGS; PDGF beta chain; PDGF Receptor beta; Pdgfr; Pdgfr1; PDGFR-1; PDGFRB; PDGF-R-beta; PDGFR-beta; PENTT; platelet derived growth factor receptor beta; platelet derived growth factor receptor, beta polypeptide; platelet-derived growth factor receptor 1; Platelet-derived growth factor receptor beta; platelet-derived growth factor receptor beta variant 1; Platelet-derived growth factor receptor, beta; platelet-derived growth factor receptor, beta polypeptide

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
18596, 5159

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P05622, P09619

Gene Symbols:
Pdgfrb

Immunogen:
A synthetic peptide derived from near the C-terminus of human PDGFR, beta

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA516590

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Antigen:
S100A6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
S100A6

Gene Alias:
2A9; 5B10; CABP; Cacy; calcium binding protein A6 (calcyclin); calcyclin; Growth factor-inducible protein 2A9; lung 10 kDa protein; MLN 4; PRA; Prolactin receptor-associated protein; protein S100-A6; S100 calcium binding protein A6; S100 calcium binding protein A6 (calcyclin); S100 calcium-binding protein A6; S100 calcium-binding protein A6 (calcyclin); S100a6

Host Species:
Rabbit

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
100033887, 101083651, 20200, 480143, 618256, 6277, 85247

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
Conc. Not Determined

Formulation:
whole serum diluted in PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
O77691, P05964, P06703, P14069

Gene Symbols:
LOC618256, S100A6

Immunogen:
Purified recombinant human S100 A6 monomer expressed in E. coli

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Equine, Feline, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA516604

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Antigen:
Human Lambda Light Chain

Classification:
Polyclonal

Conjugate:
FITC

Gene:
__

Gene Alias:
Iglc

Host Species:
Rabbit

Purification Method:
Purified

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Form:
Liquid

Applications:
Immunofluorescence

Concentration:
__

Formulation:
TBS with 1% carrier protein and 0.1% sodium azide; pH 7.4

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Lambda light chains isolated from human urine

Quantity:
2 mL

Primary or Secondary:
Secondary

Target Species:
Human

Product Type:
__

Isotype:
IgG