PIPA516616

Amphiregulin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA516616-Each-of-1 In Stock ₹ 44,533.98

PIPA516616 - Each of 1

₹ 44,533.98

In Stock

Quantity

1

Base Price: ₹ 44,533.98

GST (18%): ₹ 8,016.116

Total Price: ₹ 52,550.096

Antigen

Amphiregulin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AREG

Gene Alias

amphiregulin; amphiregulin B; AR; AREG; AREGB; colorectum cell-derived growth factor; CRDGF; Mcub; MGC13647; schwannoma-derived growth factor; SDGF

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

11839, 374

Content And Storage

4° C

Form

Liquid

Applications

Immunoprecipitation

Concentration

1 mg/mL

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.

P15514, P31955

Gene Symbols

AREG

Immunogen

A synthetic 19-mer peptide, corresponding to aa 8-26 (VKPPQNKTESENTSDKPKR) from the secreted amphiregulin of human origin

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Description

  • PA5-16616 targets Amphiregulin in IP applications and shows reactivity with Human and mouse samples
  • The PA5-16616 immunogen is a synthetic 19-mer peptide, corresponding to aa 8-26 (VKPPQNKTESENTSDKPKR) from the secreted amphiregulin of human origin
  • Amphiregulin (AR) binds to EGF-Receptor (EGFR) with lower affinity than EGF
  • The mature secreted form AR is an 84-amino acid residue glycosylated polypeptide growth regulator, which is generated by proteolytic processing of a 252-amino acid transmembrane precursor
  • Seven different polypeptide ligands, which derive from distinct genes, are capable of binding to the extracellular domain of EGFR
  • These ligands include EGF, TGFalpha, AR, HB-EGF, cripto-1, epiregulin, and betacellulin
  • All of these growth factors contain a characteristic EGF-like domain which is defined by 6 evenly spaced cysteine residues that generate 3 loops through the formation of disulfide bonds
  • AR protein has been localized by immunohistochemistry to the epithelium of the colon, stomach, pancreas, breast, and placenta
  • AR is reportedly overexpressed in human cancers of breast, colon, stomach, and pancreas.

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Img

Thermo Scientific

PIPA516616

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Antigen:
Amphiregulin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AREG

Gene Alias:
amphiregulin; amphiregulin B; AR; AREG; AREGB; colorectum cell-derived growth factor; CRDGF; Mcub; MGC13647; schwannoma-derived growth factor; SDGF

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11839, 374

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunoprecipitation

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P15514, P31955

Gene Symbols:
AREG

Immunogen:
A synthetic 19-mer peptide, corresponding to aa 8-26 (VKPPQNKTESENTSDKPKR) from the secreted amphiregulin of human origin

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA516621

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Antigen:
Amphiregulin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AREG

Gene Alias:
amphiregulin; amphiregulin B; AR; AREG; AREGB; colorectum cell-derived growth factor; CRDGF; Mcub; MGC13647; schwannoma-derived growth factor; SDGF

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11839, 374

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P15514, P31955

Gene Symbols:
AREG

Immunogen:
A synthetic 19-mer peptide, corresponding to aa 26-44 from the secreted amphiregulin of human origin

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA516629

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Antigen:
NRG1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NRG1

Gene Alias:
6030402G23Rik; Acetylcholine receptor-inducing activity; ARIA; Breast cancer cell differentiation factor p45; D230005F13Rik; GGF; GGF2; GGFII; Glial growth factor; glial growth factor 2; heregulin; heregulin, alpha (45kD, ERBB2 p185-activator); HGL; HRG; HRG1; HRGA; HRGalpha; MST131; MSTP131; NDF; Neu differentiation factor; neuregulin 1; neuregulin 1 type III beta 3; Neuregulin-1; NRG1; NRG-1; NRG1-IT2; pro-neuregulin-1, membrane-bound isoform; Pro-NRG1; sensory and motor neuron derived factor; Sensory and motor neuron-derived factor; SMDF; type I neuregulin 1; type III neuregulin 1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
211323, 3084

Content And Storage:
4° C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q02297

Gene Symbols:
NRG1

Immunogen:
A highly antigenic synthetic peptide from the EGF-like domain of human heregulin

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA516647

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Antigen:
Kappa Light Chain

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IGKV1-5

Gene Alias:
D4Mit8; HCAK1; ig kappa chain c region; Igk; Igk@; Igkc; Igk-C; IGKCD; IGKV; IGKV15; IGKV1-5; Immunoglobulin K; immunoglobulin kappa chain complex; immunoglobulin kappa constant; immunoglobulin kappa light chain; immunoglobulin kappa locus; immunoglobulin kappa variable 1-5; kappa; Kappa LC; Km; L12; L12a; LOC500183; similar to NGF-binding Ig light chain; V1

Host Species:
Rabbit

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
28299, 28901, 3514, 50802

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
__

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P01601, P01602, P01834, P0DOX7

Gene Symbols:
IGK, IGKC, IGKV1-5, IGKV1D-16

Immunogen:
kappa light chains purified from human Bence Jones proteins

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG