PIPA517079

ADAM17 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA517079-Each-of-1 In Stock ₹ 38,502.00

PIPA517079 - Each of 1

₹ 38,502.00

In Stock

Quantity

1

Base Price: ₹ 38,502.00

GST (18%): ₹ 6,930.36

Total Price: ₹ 45,432.36

Antigen

ADAM17

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ADAM17

Gene Alias

a disintegrin and metallopeptidase domain 17; a disintegrin and metalloprotease domain 17; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 17; a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme); ADAM; ADAM 17; ADAM metallopeptidase domain 17; ADAM metallopeptidase domain 18; Adam17; ADAM18; ADAMs; CD156B; CD156b antigen; CSVP; Disintegrin and metalloproteinase domain-containing protein 17; metalloendopeptidases; NISBD; NISBD1; Snake venom-like protease; TACE; TNF-alpha convertase; TNF-alpha converting enzyme; TNF-alpha-converting enzyme; tumor necrosis factor, alpha, converting enzyme

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

6868

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration

90 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

P78536

Gene Symbols

ADAM17

Immunogen

Synthetic peptide corresponding to amino acids surrounding Val200 of human TACE

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Non-human Primate

Product Type

Antibody

Isotype

IgG

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Description

  • It is not recommended to aliquot this antibody
  • ADAM17 (disintegrin and metalloproteinase domain-containing protein 17) cleaves the membrane bound precusor of TNF-alpha to its mature soluble form
  • ADAM 17 is responsbile for the proteolytical release of soluble JAM3 from endothelial cells surface and the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1, and the amyloid precursor protein
  • It acts as an activator of the Notch pathway by mediating cleavage of Notch and generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT)
  • Mutations in the gene can result in inflammatory skin and bowel disease, neonatal 1.

Compare Similar Items

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Thermo Scientific

PIPA517079

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Antigen:
ADAM17

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ADAM17

Gene Alias:
a disintegrin and metallopeptidase domain 17; a disintegrin and metalloprotease domain 17; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 17; a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme); ADAM; ADAM 17; ADAM metallopeptidase domain 17; ADAM metallopeptidase domain 18; Adam17; ADAM18; ADAMs; CD156B; CD156b antigen; CSVP; Disintegrin and metalloproteinase domain-containing protein 17; metalloendopeptidases; NISBD; NISBD1; Snake venom-like protease; TACE; TNF-alpha convertase; TNF-alpha converting enzyme; TNF-alpha-converting enzyme; tumor necrosis factor, alpha, converting enzyme

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6868

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
90 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P78536

Gene Symbols:
ADAM17

Immunogen:
Synthetic peptide corresponding to amino acids surrounding Val200 of human TACE

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517080

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Antigen:
ADAM9

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ADAM9

Gene Alias:
a disintegrin and metallopeptidase domain 9 (meltrin gamma); a disintegrin and metalloprotease domain 9; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 9 (meltrin gamma); ADAM; ADAM 9; ADAM metallopeptidase domain 9; ADAM metallopeptidase domain 9 (meltrin gamma); adam9; ADAMs; AU020942; Cellular disintegrin-related protein; cone rod dystrophy 9; CORD9; Disintegrin and metalloproteinase domain-containing protein 9; Kiaa0021; MCMP; MDC 9; MDC9; meltrin gamma; meltrin-gamma; metalloendopeptidases; Metalloprotease/disintegrin/cysteine-rich protein 9; mKIAA0021; Mltng; Myeloma cell metalloproteinase; OTTHUMP00000216481; OTTHUMP00000216484; OTTHUMP00000216485

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11502, 290834, 8754

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
44 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
Q13443, Q61072

Gene Symbols:
ADAM9

Immunogen:
Synthetic peptide corresponding to the carboxy terminus of human ADAM9

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA517082

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Antigen:
Phospho-SRC3 (Thr24)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NCOA3

Gene Alias:
2010305B15Rik; Actr; AIB1; AIB-1; amplified in breast cancer 1 protein; amplified in breast cancer-1 protein homolog; AW321064; BHLHE42; CAGH16; CBP-interacting protein; class E basic helix-loop-helix protein 42; CTG26; KAT13B; MGC141848; NCOA3; NCoA-3; Nuclear receptor coactivator 3; OTTHUMP00000031716; p/Cip; pCip; Rac3; RAC-3; Receptor-associated coactivator 3; RP5-1049G16.3; Src3; SRC-3; steroid receptor coactivator protein 3; Thyroid hormone receptor activator molecule 1; TNRC14; TNRC16; Tram1; Tram-1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8202

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
Q9Y6Q9

Gene Symbols:
NCOA3

Immunogen:
Synthetic peptide corresponding to sequence surrounding Thr24 of the human SRC-3 protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517084

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Antigen:
Phospho-FAK (Tyr397)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTK2

Gene Alias:
CG10023; CG10023-PA; CG10023-PB; CG10023-PC; CG10023-PD; CG10023-PF; CG10023-PG; CT28129; DFAK; DFak56; Dmel\CG10023; Dmel_CG10023; DmFAK; EC 2.7.10.2; Fadk; FADK 1; Fak; Fak1; Fak56; fak56D; FAK65D; Fak-PA; Fak-PB; Fak-PC; Fak-PD; Fak-PF; Fak-PG; FAK-related non-kinase polypeptide; focal adhesion kinase; Focal adhesion kinase 1; focal adhesion kinase homolog; focal adhesion kinase isoform FAK-Del33; focal adhesion kinase pp125FAK; focal adhesion kinase-related nonkinase; focal ashension kinase 1; FRNK; I79_019430; Kiaa4203; mKIAA4203; p125FAK; p41/p43FRNK; pFAK; pp125 PTK2; pp125FAK; PPP1R71; Protein phosphatase 1 regulatory subunit 71; protein phosphatase 1, regulatory subunit 71; protein tyrosine kinase 2; protein tyrosine kinase 2 L homeolog; protein-tyrosine kinase; protein-tyrosine kinase 2; PTK2; PTK2 protein tyrosine kinase 2; ptk2.L; tyrosine kinase; XELAEV_18032408mg; XPFAK

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100170770, 100759464, 102167153, 14083, 25614, 5747

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
3 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
O35346, P34152, Q05397

Gene Symbols:
PTK2

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pTyr397 of human FAK

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Hamster, Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG