PIPA517126
TMP21 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA517126-Each-of-1 | In Stock | ₹ 38,844.24 |
PIPA517126 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,844.24
GST (18%): ₹ 6,991.963
Total Price: ₹ 45,836.203
Antigen
TMP21
Classification
Polyclonal
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.
P49755, Q63584, Q9D1D4
Gene Symbols
TMED10
Immunogen
Synthetic peptide corresponding to residues of human TMP21
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Gene
TMED10
Gene Alias
1110014C03Rik; 21 kDa transmembrane trafficking protein; 21 kDa transmembrane-trafficking protein; hypothetical protein; integral membrane protein p23; integral membrane protein Tmp21-I (p23); p23; p24 family protein delta-1; P24(DELTA); p24d1; p24delta; p24delta1; S31I125; S31III125; testicular tissue protein Li 206; tmed10; tmed10.L; TMP21; Tmp-21-I; transmembrane emp24 domain-containing protein 10; transmembrane emp24-like trafficking protein 10; transmembrane emp24-like trafficking protein 10 (yeast); transmembrane p24 trafficking protein 10; transmembrane p24 trafficking protein 10 L homeolog; transmembrane protein; transmembrane protein tmp21; transmembrane trafficking protein; transmembrane trafficking protein 21; XELAEV_18000191mg; Xp24d2; Xp24delta2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
10972, 68581, 84599
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- It is not recommended to aliquot this antibody
- TMP21 is a ubiquitously expressed protein that is involved in vesicular targeting and protein transport
- More recent experiments have shown that it is also a component in the presenilin complex and modulates the -gamma-secretase but not the epsilon-secretase cleavage activity of the amyloid precursor protein
- The presenilin complex is composed of the proteins APH1, nicastrin, and PEN2 in addition to presenilin-1
- Together, these proteins cleave the amyloid precursor protein at what is known as the -gamma- and epsilon-sites and can lead to the accumulation of the Abeta cleavage product that is associated with Alzheimer's disease
- Co-immunoprecipitation experiments using antibodies against these proteins also yielded TMP21 indicating that TMP21 may play a role in the regulation of this complex
- Suppression of TMP21 expression by siRNA in transfected cells caused increased -gamma-secretase activity but not epsilon-secretase activity, and increased Abeta production, demonstrating that TMP21 can modulate -gamma-secretase activity.
Compare Similar Items
Show Difference
Antigen: TMP21
Classification: Polyclonal
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: P49755, Q63584, Q9D1D4
Gene Symbols: TMED10
Immunogen: Synthetic peptide corresponding to residues of human TMP21
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: TMED10
Gene Alias: 1110014C03Rik; 21 kDa transmembrane trafficking protein; 21 kDa transmembrane-trafficking protein; hypothetical protein; integral membrane protein p23; integral membrane protein Tmp21-I (p23); p23; p24 family protein delta-1; P24(DELTA); p24d1; p24delta; p24delta1; S31I125; S31III125; testicular tissue protein Li 206; tmed10; tmed10.L; TMP21; Tmp-21-I; transmembrane emp24 domain-containing protein 10; transmembrane emp24-like trafficking protein 10; transmembrane emp24-like trafficking protein 10 (yeast); transmembrane p24 trafficking protein 10; transmembrane p24 trafficking protein 10 L homeolog; transmembrane protein; transmembrane protein tmp21; transmembrane trafficking protein; transmembrane trafficking protein 21; XELAEV_18000191mg; Xp24d2; Xp24delta2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10972, 68581, 84599
Content And Storage: -20°C
Form: Liquid
Antigen:
TMP21
Classification:
Polyclonal
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.:
P49755, Q63584, Q9D1D4
Gene Symbols:
TMED10
Immunogen:
Synthetic peptide corresponding to residues of human TMP21
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
TMED10
Gene Alias:
1110014C03Rik; 21 kDa transmembrane trafficking protein; 21 kDa transmembrane-trafficking protein; hypothetical protein; integral membrane protein p23; integral membrane protein Tmp21-I (p23); p23; p24 family protein delta-1; P24(DELTA); p24d1; p24delta; p24delta1; S31I125; S31III125; testicular tissue protein Li 206; tmed10; tmed10.L; TMP21; Tmp-21-I; transmembrane emp24 domain-containing protein 10; transmembrane emp24-like trafficking protein 10; transmembrane emp24-like trafficking protein 10 (yeast); transmembrane p24 trafficking protein 10; transmembrane p24 trafficking protein 10 L homeolog; transmembrane protein; transmembrane protein tmp21; transmembrane trafficking protein; transmembrane trafficking protein 21; XELAEV_18000191mg; Xp24d2; Xp24delta2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10972, 68581, 84599
Content And Storage:
-20°C
Form:
Liquid
Antigen: CDK7
Classification: Polyclonal
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: P50613, P51952, Q03147
Gene Symbols: CDK7
Immunogen: Synthetic peptide corresponding to the amino terminus of human CDK7
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: CDK7
Gene Alias: 39 KDa protein kinase; 39 protein kinase; AI323415; AI528512; C230069N13; CAK; CAK1; CDK; CDK7; CDK-activating kinase; CDK-activating kinase 1; Cdkn7; cell division protein kinase 7; CR4 protein kinase; CRK4; CRK4 PK (CDC2-related-kinase-4 protein kinase); cyclin dependent kinase 7; cyclin-dependent kinase 7; cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase); cyclin-dependent kinase 7 (MO15 homolog Xenopus laevis cdk-activating kinase); cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase); EC 2.7.11.22; EC 2.7.11.23; HCAK; homolog of Xenopus MO15 Cdk-activating kinase; kinase subunit of CAK; MO15; Mpk-7; OTTHUMP00000222032; OTTHUMP00000222033; p39 Mo15; p39MO15; Protein-tyrosine kinase MPK-7; serine/threonine kinase stk1; serine/threonine protein kinase 1; serine/threonine protein kinase MO15; Serine/threonine-protein kinase 1; STK1; TFIIH basal transcription factor complex kinase subunit
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1022, 12572, 171150
Content And Storage: -20°C
Form: Liquid
Antigen:
CDK7
Classification:
Polyclonal
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.:
P50613, P51952, Q03147
Gene Symbols:
CDK7
Immunogen:
Synthetic peptide corresponding to the amino terminus of human CDK7
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
CDK7
Gene Alias:
39 KDa protein kinase; 39 protein kinase; AI323415; AI528512; C230069N13; CAK; CAK1; CDK; CDK7; CDK-activating kinase; CDK-activating kinase 1; Cdkn7; cell division protein kinase 7; CR4 protein kinase; CRK4; CRK4 PK (CDC2-related-kinase-4 protein kinase); cyclin dependent kinase 7; cyclin-dependent kinase 7; cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase); cyclin-dependent kinase 7 (MO15 homolog Xenopus laevis cdk-activating kinase); cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase); EC 2.7.11.22; EC 2.7.11.23; HCAK; homolog of Xenopus MO15 Cdk-activating kinase; kinase subunit of CAK; MO15; Mpk-7; OTTHUMP00000222032; OTTHUMP00000222033; p39 Mo15; p39MO15; Protein-tyrosine kinase MPK-7; serine/threonine kinase stk1; serine/threonine protein kinase 1; serine/threonine protein kinase MO15; Serine/threonine-protein kinase 1; STK1; TFIIH basal transcription factor complex kinase subunit
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1022, 12572, 171150
Content And Storage:
-20°C
Form:
Liquid
Antigen: Phospho-CRMP2 (Thr514)
Classification: Polyclonal
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: O08553, P47942, Q16555
Gene Symbols: DPYSL2
Immunogen: Synthetic peptide surrounding Thr514 of human CRMP-2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: DPYSL2
Gene Alias: AI851130; collapsin response mediator protein 2; collapsin response mediator protein hCRMP-2; CRMP2; CRMP-2; DHPRP2; dihydropyrimidinase like 2; dihydropyrimidinase-like 2; dihydropyrimidinase-related protein 2; DPYL2; Dpysl2; DRP2; DRP-2; Musunc33; N2A3; Neural-specific protein NSP60; TOAD-64; turned on after division 64; turned on after division 64 kDa protein; turned on after division, 64 kDa protein; ULIP2; ULIP-2; unc-33-like phosphoprotein 2; Unknown (protein for MGC:137406)
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12934, 1808, 25416
Content And Storage: -20°C
Form: Liquid
Antigen:
Phospho-CRMP2 (Thr514)
Classification:
Polyclonal
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.:
O08553, P47942, Q16555
Gene Symbols:
DPYSL2
Immunogen:
Synthetic peptide surrounding Thr514 of human CRMP-2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
DPYSL2
Gene Alias:
AI851130; collapsin response mediator protein 2; collapsin response mediator protein hCRMP-2; CRMP2; CRMP-2; DHPRP2; dihydropyrimidinase like 2; dihydropyrimidinase-like 2; dihydropyrimidinase-related protein 2; DPYL2; Dpysl2; DRP2; DRP-2; Musunc33; N2A3; Neural-specific protein NSP60; TOAD-64; turned on after division 64; turned on after division 64 kDa protein; turned on after division, 64 kDa protein; ULIP2; ULIP-2; unc-33-like phosphoprotein 2; Unknown (protein for MGC:137406)
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12934, 1808, 25416
Content And Storage:
-20°C
Form:
Liquid
Antigen: TLR1
Classification: Polyclonal
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: Q15399
Gene Symbols: TLR1
Immunogen: Synthetic peptide corresponding to residues at the amino terminus of human TLR1 protein
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Non-human Primate
Product Type: Antibody
Isotype: IgG
Applications: Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Gene: TLR1
Gene Alias: CD281; KIAA0012; rsc786; TIL; TIL. LPRS5; TLR1; toll like receptor 1; Toll/interleukin-1 receptor-like protein; toll-like receptor 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7096
Content And Storage: -20°C
Form: Liquid
Antigen:
TLR1
Classification:
Polyclonal
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.:
Q15399
Gene Symbols:
TLR1
Immunogen:
Synthetic peptide corresponding to residues at the amino terminus of human TLR1 protein
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Gene:
TLR1
Gene Alias:
CD281; KIAA0012; rsc786; TIL; TIL. LPRS5; TLR1; toll like receptor 1; Toll/interleukin-1 receptor-like protein; toll-like receptor 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7096
Content And Storage:
-20°C
Form:
Liquid