MYPT1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA517164-Each-of-1 | In Stock | ₹ 50,223.72 |
PIPA517164 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,223.72
GST (18%): ₹ 9,040.27
Total Price: ₹ 59,263.99
Antigen
MYPT1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PPP1R12A
Gene Alias
1200015F06Rik; 130 kDa myosin-binding subunit of smooth muscle myosin phophatase; 130 kDa myosin-binding subunit of smooth muscle myosin phophatase (M130); 130 kDa myosin-binding subunit of smooth muscle myosin phosphatase; 130 kDa regulatory subunit of myosin phosphatase; 133kDa myosin-binding subunit of smooth muscle myosin phosphatase (M133); 5730577I22Rik; AA792106; AV099298; D10Ertd625e; hypothetical protein; I79_016312; LOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 12A; M110; M130; M130 of smooth muscle myosin phosphatase; MBS; MBSP; myosin binding subunit; myosin phosphatase target subunit 1; myosin phosphatase, target subunit 1; myosin phosphatase-targeting subunit 1; myosin-binding subunit of myosin phosphatase; Mypt1; PP-1M; PP1M M110 subunit; PP1M subunit M110; Ppp1r12a; Protein phosphatase 1 regulatory subunit 12A; protein phosphatase 1, regulatory (inhibitor) subunit 12A; protein phosphatase 1, regulatory subunit 12A; protein phosphatase 1M 110 kda regulatory subunit; protein phosphatase myosin-binding subunit; Protein phosphatase subunit 1M; serine/threonine protein phosphatase PP1 smooth muscle regulatory subunit M110; si:dkey-28j4.1; smooth muscle myosin phosphatase myosin-binding subunit; unm p82emcf; unm_p82emcf; zgc:110448; zgc:110448 protein
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100754718, 116670, 17931, 4659
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
5 μg/mL
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.
O14974, Q10728, Q9DBR7
Gene Symbols
PPP1R12A
Immunogen
Synthetic peptide correspondent to amino-terminal residues of human MYPT1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Hamster, Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG
Description
- It is not recommended to aliquot this antibody
- This antibody is not cross-reactive with other family members
- Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase
- Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho
- The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells
- The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP
- RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC
- Rho-associated kinase (Rho-kinase), which is activated by GTP
- RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase
- Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosphorylation of MBS and MLC
- Thus, Rho appears to inhibit myosin phosphatase through the action of Rho-kinase
- Several transcript variants encoding different isoforms have been found for this gene.
Compare Similar Items
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Antigen: MYPT1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PPP1R12A
Gene Alias: 1200015F06Rik; 130 kDa myosin-binding subunit of smooth muscle myosin phophatase; 130 kDa myosin-binding subunit of smooth muscle myosin phophatase (M130); 130 kDa myosin-binding subunit of smooth muscle myosin phosphatase; 130 kDa regulatory subunit of myosin phosphatase; 133kDa myosin-binding subunit of smooth muscle myosin phosphatase (M133); 5730577I22Rik; AA792106; AV099298; D10Ertd625e; hypothetical protein; I79_016312; LOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 12A; M110; M130; M130 of smooth muscle myosin phosphatase; MBS; MBSP; myosin binding subunit; myosin phosphatase target subunit 1; myosin phosphatase, target subunit 1; myosin phosphatase-targeting subunit 1; myosin-binding subunit of myosin phosphatase; Mypt1; PP-1M; PP1M M110 subunit; PP1M subunit M110; Ppp1r12a; Protein phosphatase 1 regulatory subunit 12A; protein phosphatase 1, regulatory (inhibitor) subunit 12A; protein phosphatase 1, regulatory subunit 12A; protein phosphatase 1M 110 kda regulatory subunit; protein phosphatase myosin-binding subunit; Protein phosphatase subunit 1M; serine/threonine protein phosphatase PP1 smooth muscle regulatory subunit M110; si:dkey-28j4.1; smooth muscle myosin phosphatase myosin-binding subunit; unm p82emcf; unm_p82emcf; zgc:110448; zgc:110448 protein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100754718, 116670, 17931, 4659
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 5 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: O14974, Q10728, Q9DBR7
Gene Symbols: PPP1R12A
Immunogen: Synthetic peptide correspondent to amino-terminal residues of human MYPT1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Hamster, Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Antigen: DDX3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DDX3X
Gene Alias: ATP-dependent RNA helicase DDX3X; CAP-Rf; D1Pas1-related sequence 2; D1Pas1-rs2; DBX; DDX14; DDX3; Ddx3x; D-E-A-D (aspartate-glutamate-alanine-aspartate) box polypeptide 3; DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 3; DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked; DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked; DEAD box protein 3, X-chromosomal; DEAD box RNA helicase DEAD3; DEAD box, X isoform; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked; DEAD/H box-3; Dead3; DEAD-box helicase 3, X-linked; DEAD-box protein 3 (DEAD-box RNA helicase DEAD3) (mDEAD3) (Embryonic RNA helicase) (D1PAS1 related sequence 2); Embryonic RNA helicase; Erh; fibroblast growth factor inducible 14; Fin14; Helicase-like protein 2; HLP2; mDEAD3; MRX102
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100764307, 13205, 1654, 317335
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: __
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: O00571, Q62167
Gene Symbols: DDX3X
Immunogen: Synthetic peptide corresponding to the amino-terminal sequence of human DDX3
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Hamster, Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Antigen: Caspr2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CNTNAP2
Gene Alias: 5430425M22Rik; AUTS15; CASPR2; CDFE; Cell recognition molecule Caspr2; Cntnap2; contactin associated protein-like 2; contactin-associated protein-like 2; DKFZp781D1846; homolog of Drosophila neurexin IV; KIAA0868; mKIAA0868; NRXN4; PTHSL1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26047, 500105, 66797
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: __
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: Q9CPW0, Q9UHC6
Gene Symbols: CNTNAP2
Immunogen: Synthetic peptide sourrounding Glu1320 of human Caspr2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
