PIPA517197

Phospho-CDK9 (Thr186) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA517197-Each-of-1 In Stock ₹ 44,705.10

PIPA517197 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-CDK9 (Thr186)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CDK9

Gene Alias

C-2k; CDC2L4; CDC2-related kinase; Cdk9; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; CTK1; cyclin dependent kinase 9; cyclin-dependent kinase 9; cyclin-dependent kinase 9 (CDC2-related kinase); PITALRE; RP11-228B15.5; serine/threonine protein kinase PITALRE; Serine/threonine-protein kinase PITALRE; TAK; Tat-associated kinase complex catalytic subunit

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1025, 107951, 362110

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

126 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

P50750, Q641Z4, Q99J95

Gene Symbols

CDK9

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding pThr186 of human CDK9

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

Description

  • It is not recommended to aliquot this antibody
  • CDK9 is a serine/threonine kinase which when complexed with CyclinT1 forms an active holoenzyme complex
  • This complex plays a key role in regulating the eukaryotic cell cycle
  • CDK9 is coexpressed and copurified with CyclinT1
  • CDK9 regulates cytokine inducible transcription networks by facilitating promoter recognition of target transcription factors
  • CDK9 promotes RNA synthesis in genetic programs for cell growth, differentiation, and viral pathogenesis
  • The CDK9/cyclin-K complex also has kinase activity towards CTD of RNAPII and can substitute for CDK9/cyclin-T P-TEFb in vitro
  • Chronic activation of CDK9 causes cardiac myocyte enlargement leading to cardiac hypertrophy and confers a predisposition to heart failure.

Compare Similar Items

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Img

Thermo Scientific

PIPA517197

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Antigen:
Phospho-CDK9 (Thr186)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDK9

Gene Alias:
C-2k; CDC2L4; CDC2-related kinase; Cdk9; Cell division cycle 2-like protein kinase 4; Cell division protein kinase 9; CTK1; cyclin dependent kinase 9; cyclin-dependent kinase 9; cyclin-dependent kinase 9 (CDC2-related kinase); PITALRE; RP11-228B15.5; serine/threonine protein kinase PITALRE; Serine/threonine-protein kinase PITALRE; TAK; Tat-associated kinase complex catalytic subunit

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1025, 107951, 362110

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
126 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P50750, Q641Z4, Q99J95

Gene Symbols:
CDK9

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pThr186 of human CDK9

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517198

--


Antigen:
XLF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NHEJ1

Gene Alias:
1700029B21Rik; cernunnos; FLJ12610; Nhej1; non-homologous end joining factor 1; non-homologous end-joining factor 1; nonhomologous end-joining factor 1; protein cernunnos; Xlf; XRCC4-like factor

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
79840

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
Q9H9Q4

Gene Symbols:
NHEJ1

Immunogen:
Synthetic peptide corresponding to amino acids near the carboxy terminus of human XLF

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517200

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Antigen:
INCENP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Incenp

Gene Alias:
2700067E22Rik; AU019509; binds and activates aurora-B and -C in vivo and in vitro; C130081E20; C77457; chromosomal passenger protein; Incenp; Inner centromere protein; inner centromere protein antigens 135/155kDa; inner centromere protein INCENP

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3619

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Concentration:
7.7 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
Q9NQS7

Gene Symbols:
Incenp

Immunogen:
Synthetic peptide corresponding to amino acids surrounding Ala841 of human INCENP

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517201

--


Antigen:
INCENP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Incenp

Gene Alias:
2700067E22Rik; AU019509; binds and activates aurora-B and -C in vivo and in vitro; C130081E20; C77457; chromosomal passenger protein; Incenp; Inner centromere protein; inner centromere protein antigens 135/155kDa; inner centromere protein INCENP

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3619

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
Q9NQS7

Gene Symbols:
Incenp

Immunogen:
Synthetic peptide corresponding to amino acids surrounding Pro240 of human INCENP

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG