PIPA517217

ATG12 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA517217-Each-of-1 In Stock ₹ 41,796.06

PIPA517217 - Each of 1

₹ 41,796.06

In Stock

Quantity

1

Base Price: ₹ 41,796.06

GST (18%): ₹ 7,523.291

Total Price: ₹ 49,319.351

Antigen

ATG12

Classification

Polyclonal

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

O94817

Gene Symbols

ATG12

Immunogen

Synthetic peptide corresponding to residues near the amino terminus of human Atg12

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Western Blot

Conjugate

Unconjugated

Gene

ATG12

Gene Alias

4931423H11Rik; A330058M13Rik; APG 12; APG12; Apg12 (autophagy, yeast) homolog; APG12L; APG12-like; ATG12; ATG12 autophagy related 12 homolog; Atg12l; Atg12p; Atg12-PB; Autophagy protein 12-like; autophagy related 12; autophagy related protein 12; autophagy-related 12; autophagy-related protein 12; Autophagy-specific gene 12; CG10861; CG10861-PB; Dmel\CG10861; Dmel_CG10861; FBR93; HAPG12; IP05205p; IP05405p; OTTHUMP00000159129; ubiquitin-like protein ATG12; YBR1506; YBR217W

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9140

Content And Storage

-20°C

Form

Liquid

Description

  • It is not recommended to aliquot this antibody
  • ATG12, a member of the autophagy protein family, forms a conjugate with ATG5; this conjugate has a ubiquitin-protein ligase (E3)-like activity for protein lipidation in autophagy
  • This conjugate also associates with innate immune response proteins such as RIG-I and VISA (also known as IPS-1), inhibiting type I interferon production and permitting viral replication in host cells
  • ATG12 has also been shown to interact with ATG10 in human embryonic kidney cells in the presence of ATG7
  • At least two isoforms of ATG12 are known to exist
  • Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells
  • It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components
  • This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1.

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Img

Thermo Scientific

PIPA517217

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Antigen:
ATG12

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
O94817

Gene Symbols:
ATG12

Immunogen:
Synthetic peptide corresponding to residues near the amino terminus of human Atg12

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
ATG12

Gene Alias:
4931423H11Rik; A330058M13Rik; APG 12; APG12; Apg12 (autophagy, yeast) homolog; APG12L; APG12-like; ATG12; ATG12 autophagy related 12 homolog; Atg12l; Atg12p; Atg12-PB; Autophagy protein 12-like; autophagy related 12; autophagy related protein 12; autophagy-related 12; autophagy-related protein 12; Autophagy-specific gene 12; CG10861; CG10861-PB; Dmel\CG10861; Dmel_CG10861; FBR93; HAPG12; IP05205p; IP05405p; OTTHUMP00000159129; ubiquitin-like protein ATG12; YBR1506; YBR217W

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9140

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIPA517221

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Antigen:
IKK epsilon

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
Q14164, Q9R0T8

Gene Symbols:
IKBKE

Immunogen:
Synthetic peptide corresponding to a region near the carboxyl terminus of IKKe protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
IKBKE

Gene Alias:
AW558201; I-kappa-B kinase epsilon; Ikbke; IKKE; IKK-E; IKKepsilon; IKK-epsilon; IKKI; IKK-i; IKK-related kinase epsilon; inducible I kappa-B kinase; inducible IkappaB kinase; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon; inhibitor of kappaB kinase epsilon; inhibitor of nuclear factor kappa-B kinase subunit epsilon; KIAA0151; RP11-534L20.1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
363984, 56489, 9641

Content And Storage:
-20°C

Form:
Liquid

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Thermo Scientific

PIPA517222

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Antigen:
Blooms Syndrome

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P54132

Gene Symbols:
BLM

Immunogen:
Synthetic peptide corresponding to residues near the amino terminus of human BLM

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
BLM

Gene Alias:
Blm; Bloom syndrome homolog; Bloom syndrome protein; Bloom syndrome protein homolog; Bloom syndrome RecQ like helicase; Bloom syndrome, RecQ helicase-like; BS; DNA helicase, RecQ-like type 2; mBLM; MGC126616; MGC131618; MGC131620; RecQ helicase homolog; recQ protein-like 3; RecQ2; RECQL2; RECQL3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
641

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIPA517223

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Antigen:
PBX1

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P40424, P41778

Gene Symbols:
PBX1

Immunogen:
Synthetic peptide corresponding to amino acids near the amino terminus of human Pbx1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
ChIP Assay, Immunocytochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
PBX1

Gene Alias:
2310056B04Rik; D230003C07Rik; DKFZp686B09108; Homeobox protein PBX1; homeobox protein PRL; MGC126627; OTTHUMP00000032205; PBX homeobox 1; Pbx1; Pbx-1; pre B cell leukemia homeobox 1; pre-B-cell leukemia homeobox 1; pre-B-cell leukemia transcription factor 1; PRL

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18514, 5087

Content And Storage:
-20°C

Form:
Liquid