PIPA517247

Huntingtin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA517247-Each-of-1 In Stock ₹ 42,394.98

PIPA517247 - Each of 1

₹ 42,394.98

In Stock

Quantity

1

Base Price: ₹ 42,394.98

GST (18%): ₹ 7,631.096

Total Price: ₹ 50,026.076

Antigen

Huntingtin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Htt

Gene Alias

AI256365; C430023I11Rik; Hd; HD protein; HD protein homolog; Hdh; HTT; Huntingtin; huntingtin (Huntington disease); Huntingtin, myristoylated N-terminal fragment; Huntington disease gene homolog; huntington disease protein; huntington disease protein homolog; IT15; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

15194, 29424, 3064

Content And Storage

-20°C

Form

Liquid

Applications

Immunoprecipitation, Western Blot

Concentration

14 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

P42858, P42859, P51111

Gene Symbols

Htt

Immunogen

Synthetic peptide surrounding Pro1220 of human huntingtin.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • It is not recommended to aliquot this antibody
  • Huntingtin is a disease gene linked to Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons
  • This is thought to be caused by an expanded, unstable trinucleotide repeat in the huntingtin gene, which translates as a polyglutamine repeat in the protein product
  • HD is a mid-life onset autosomal dominant neurodegenerative disease that is characterized by psychiatric disorders, dementia, and involuntary movements (chorea), leading to death in 10-20 years.The huntingtin locus is large, spanning 180 kb and consisting of 67 exons
  • The huntingtin gene is widely expressed and is required for normal development
  • It is expressed as 2 alternatively polyadenylated forms displaying different relative abundance in various fetal and adult tissues
  • The larger transcript is approximately 13.7 kb and is expressed predominantly in adult and fetal brain whereas the smaller transcript of approximately 10.3 kb is more widely expressed
  • The genetic defect leading to Huntington's disease may not necessarily eliminate transcription, but may confer a new property on the mRNA or alter the function of the protein.

Compare Similar Items

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Img

Thermo Scientific

PIPA517247

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Antigen:
Huntingtin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Htt

Gene Alias:
AI256365; C430023I11Rik; Hd; HD protein; HD protein homolog; Hdh; HTT; Huntingtin; huntingtin (Huntington disease); Huntingtin, myristoylated N-terminal fragment; Huntington disease gene homolog; huntington disease protein; huntington disease protein homolog; IT15; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15194, 29424, 3064

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
14 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P42858, P42859, P51111

Gene Symbols:
Htt

Immunogen:
Synthetic peptide surrounding Pro1220 of human huntingtin.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517252

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Antigen:
IRF2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IRF2

Gene Alias:
9830146E22Rik; AI646973; DKFZp686F0244; Interferon regulatory factor 2; IRF2; Irf-2; OTTHUMP00000218576; OTTHUMP00000218580

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16363, 290749, 3660

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P14316, P23906

Gene Symbols:
IRF2

Immunogen:
Synthetic peptide corresponding to residues surrounding Asp327 of human IRF-2 protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

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Thermo Scientific

PIPA517254

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Antigen:
IRF4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IRF4

Gene Alias:
AI385587; interferon regulatory factor 4; Irf4; IRF-4; LSIRF; Lymphocyte-specific interferon regulatory factor; multiple myeloma oncogene 1; MUM1; NF-EM5; PU.1 interaction partner; Sfpi1/PU.1 interaction partner; SHEP8; Spip; Transcriptional activator PIP

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16364, 291100, 3662

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
Q15306, Q64287

Gene Symbols:
IRF4

Immunogen:
Synthetic peptide corresponding to residues around Pro173 of human IRF-4 protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517255

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Antigen:
IRF5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IRF5

Gene Alias:
AW491843; Interferon regulatory factor 5; interferon regulatory factor 5 bone marrow; IRF5; IRF-5; mirf5; OTTHUMP00000212907; SLEB10

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27056, 296953, 3663

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
40 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P56477, Q13568

Gene Symbols:
IRF5

Immunogen:
Synthetic peptide corresponding to residues surrounding Ser172 of mouse IRF-5 protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG