PIPA517256

MAVS Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA517256-Each-of-1 In Stock ₹ 44,533.98

PIPA517256 - Each of 1

₹ 44,533.98

In Stock

Quantity

1

Base Price: ₹ 44,533.98

GST (18%): ₹ 8,016.116

Total Price: ₹ 52,550.096

Antigen

MAVS

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAVS

Gene Alias

CARD adapter inducing interferon beta; CARD adaptor inducing IFN-beta; Cardif; D430028G21Rik; IFN-B promoter stimulator 1; IFN-beta promoter stimulator-1; interferon beta promoter stimulator protein 1; interferon-beta promoter stimulator protein 1; IPS1; IPS-1; KIAA1271; MAVS; mitochondrial antiviral signaling protein; mitochondrial anti-viral signaling protein; mitochondrial antiviral-signaling protein; Putative NF-kappa-B-activating protein 031N; virus-induced signaling adapter; virus-induced signaling adaptor; virus-induced-signaling adapter; VISA

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

57506

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

71 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

Q7Z434

Gene Symbols

MAVS

Immunogen

Synthetic peptide corresponding to residues at the carboxyl terminus of human MAVS

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • It is not recommended to aliquot this antibody
  • Two distinct signaling pathways activate the host innate immunity against viral infection
  • One pathway is reliant on members of the Toll-like receptor (TLR) family while the other uses the RNA helicase RIG-I as a receptor for intracellular viral double-stranded RNA as a trigger for the immune response
  • MAVS is a mitochondrial membrane protein that was identified as a critical component in the IFN beta signaling pathways that recruits IRF-3 to RIG-I, leading to its activation and that of NF-kappa-B
  • MAVS is also thought to interact with other components of the innate immune pathway such as the TLR adapter protein TRIF, TRAF2 and TRAF6
  • MAVS also interacts with the IKK-alpha, IKK-beta and IKK-iota kinases through its C-terminal region
  • Cleavage of this region by the Hepatitis C virus (HCV) protease allows HCV to escape the host immune system
  • Multiple isoforms of MAVS are known to exist.

Compare Similar Items

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Img

Thermo Scientific

PIPA517256

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Antigen:
MAVS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAVS

Gene Alias:
CARD adapter inducing interferon beta; CARD adaptor inducing IFN-beta; Cardif; D430028G21Rik; IFN-B promoter stimulator 1; IFN-beta promoter stimulator-1; interferon beta promoter stimulator protein 1; interferon-beta promoter stimulator protein 1; IPS1; IPS-1; KIAA1271; MAVS; mitochondrial antiviral signaling protein; mitochondrial anti-viral signaling protein; mitochondrial antiviral-signaling protein; Putative NF-kappa-B-activating protein 031N; virus-induced signaling adapter; virus-induced signaling adaptor; virus-induced-signaling adapter; VISA

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
57506

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
71 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
Q7Z434

Gene Symbols:
MAVS

Immunogen:
Synthetic peptide corresponding to residues at the carboxyl terminus of human MAVS

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517257

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Antigen:
HK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Hk2

Gene Alias:
AI642394; DKFZp686M1669; Hexokinase; hexokinase 2; hexokinase II; hexokinase type II; Hexokinase-2; hexokinase-2 muscle; hexokinase-2, muscle; Hexokinase-B; HK II; Hk2; HKII; HXK2; muscle form hexokinase; OTTHUMP00000202738

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3099

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P52789

Gene Symbols:
Hk2

Immunogen:
Synthetic peptide corresponding to the sequence of human hexokinase (isoform II)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517258

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Antigen:
eIF4A1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EIF4A1

Gene Alias:
ATP-dependent RNA helicase eIF4A-1; BM-010; DDX2A; Eif4; EIF4A; EIF-4A; Eif4a1; eIF-4A-I; eIF4A-I; eukaryotic initiation factor 4AI; Eukaryotic initiation factor 4A-I; eukaryotic translation initiation factor 4A, isoform 1; eukaryotic translation initiation factor 4A1; initiation factor eIF-4A long form; QtsA-12280; unnamed protein product

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13681, 1973, 287436

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P60842, P60843

Gene Symbols:
EIF4A1

Immunogen:
Synthetic peptide corresponding to residues surrounding Phe52 of human eIF4A

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517259

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Antigen:
PSMD4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Psmd4

Gene Alias:
26S proteasome non-ATPase regulatory subunit 4; 26S proteasome regulatory subunit RPN10; 26S proteasome regulatory subunit S5A; AF; Af1; AF-1; angiocidin; anti secretory factor 1; antisecretory factor; antisecretory factor 1; ASF; Mcb1; multiubiquitin chain-binding protein; multiubiquitin-chain-binding protein; proteasome (prosome, macropain) 26S subunit, non-ATPase, 4; proteasome 26S subunit, non-ATPase 4; Psmd4; pUB-R5; RP11-126K1.1; Rpn10; RPN10 homolog; S5A; S5a/antisecretory factor protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19185, 5710, 83499

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
76 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
O35226, P55036

Gene Symbols:
Psmd4

Immunogen:
Synthetic peptide corresponding to residues surrounding Gly344 of human S5a/PSMD4 protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG