PIPA517324

ERO1L Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA517324-Each-of-1 In Stock ₹ 38,844.24

PIPA517324 - Each of 1

₹ 38,844.24

In Stock

Quantity

1

Base Price: ₹ 38,844.24

GST (18%): ₹ 6,991.963

Total Price: ₹ 45,836.203

Antigen

ERO1L

Classification

Polyclonal

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

Q96HE7

Gene Symbols

ERO1A

Immunogen

Synthetic peptide corresponding to residues surrounding Leu218 of human Ero1-La

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Conjugate

Unconjugated

Gene

ERO1A

Gene Alias

Endoplasmic oxidoreductin-1-like protein; endoplasmic reticulum oxidation 1; endoplasmic reticulum oxidoreductase 1 alpha; endoplasmic reticulum oxidoreductase alpha; Endoplasmic reticulum oxidoreductin-1-like protein; ero1; ERO1A; Ero1alpha; ERO1-alpha; ERO1L; ERO1-L; ERO1LA; ERO1-L-alpha; ERO1-like; ERO1-like (S. cerevisiae); ERO1-like protein alpha; Giig11; Global ischemia-induced protein 11; oxidoreductin-1-L-alpha; UNQ434/PRO865

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

30001

Content And Storage

-20°C

Form

Liquid

Description

  • It is not recommended to aliquot this antibody
  • ERO1L (endoplasmic oxidoreductin-1-like protein) is localized in ER membrane as peripheral membrane protein on the lumenal side
  • Its association with ERP44 is essential for its retention in the ER and is unique in coupling oxygen reduction to de novo disulfides formation
  • The ERO1L enzyme is broadly distributed at low levels in several tissues with highest levels in the upper digestive tract and is stimulated by hypoxia via HIF-signaling
  • ERO1L generally exists as monomer, but has the ability to function as monomer or homodimer and interacts with PDILT
  • After translation, ERO1L gets n-glycosylated and the disulfide bonds constitute the redox-active center whereby the Cys-94/Cys-99 disulfide bond accepts an electron from P4HB followed by funneling the same to the active site disulfide Cys-394/Cys-397
  • ERO1L acts by oxidizing directly to P4HB/PDI isomerase through direct disulfide exchange and associates with ERP44
  • ERO1L is implicated in immunoglobulin folding, oxidative stress, release of unfolded cholera toxin from reduced P4HB/PDI upon Vibrio cholerae infection, and plays a key role in ER stress-induced CHOP-dependent apoptosis through inositol 1,4,5-trisphosphate receptor IP3R1 activation.

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Thermo Scientific

PIPA517324

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Antigen:
ERO1L

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
Q96HE7

Gene Symbols:
ERO1A

Immunogen:
Synthetic peptide corresponding to residues surrounding Leu218 of human Ero1-La

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
ERO1A

Gene Alias:
Endoplasmic oxidoreductin-1-like protein; endoplasmic reticulum oxidation 1; endoplasmic reticulum oxidoreductase 1 alpha; endoplasmic reticulum oxidoreductase alpha; Endoplasmic reticulum oxidoreductin-1-like protein; ero1; ERO1A; Ero1alpha; ERO1-alpha; ERO1L; ERO1-L; ERO1LA; ERO1-L-alpha; ERO1-like; ERO1-like (S. cerevisiae); ERO1-like protein alpha; Giig11; Global ischemia-induced protein 11; oxidoreductin-1-L-alpha; UNQ434/PRO865

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
30001

Content And Storage:
-20°C

Form:
Liquid

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PIPA517330

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Antigen:
AP2 gamma

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
Q92754

Gene Symbols:
TFAP2C

Immunogen:
Synthetic peptide corresponding to the sequence of human AP-2 gamma

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ChIP Assay, Immunocytochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
TFAP2C

Gene Alias:
AA409384; activating enhancer binding protein 2 gamma; activating enhancer-binding protein 2 gamma; activator protein 2 gamma; AP-2.2; AP2gamma; AP2-GAMMA; ERF1; estrogen receptor factor 1; hAP-2g; stimulated by retinoic acid gene 2; Stra2; Tcfap2c; TFAP2C; TFAP2G; Transcription factor AP-2 gamma; transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma); transcription factor AP-2 gamma (activating enhancer-binding protein 2 gamma); transcription factor AP-2, gamma; transcription factor ERF-1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7022

Content And Storage:
-20°C

Form:
Liquid

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PIPA517331

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Antigen:
SCD

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
O00767, P13516

Gene Symbols:
Scd, Scd1

Immunogen:
Synthetic peptide corresponding to residues surrounding M38 of human SCD1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Conjugate:
Unconjugated

Gene:
Scd

Gene Alias:
AA589638; ab; acyl-CoA desaturase; Acyl-CoA desaturase 1; acyl-CoA desaturase 2; AI265570; asebia; delta(9)-desaturase; Delta(9)-desaturase 1; delta(9)-desaturase 2; Delta-9 desaturase; delta-9 desaturase 1; Delta-9 desaturase 2; delta-9-desaturase; FADS5; fatty acid desaturase; Fatty acid desaturase 1; fatty acid desaturase 2; HGNC:10571; hSCD1; MSTP008; OTTHUMP00000020280; predicted protein of HQ0998; PRO0998; PRO1933; Scd; Scd1; Scd-1; Scd2; SCDOS; stearoyl-CoA desaturase; stearoyl-CoA desaturase (delta-9-desaturase); stearoyl-CoA desaturase 1; Stearoyl-CoA desaturase 2; stearoyl-CoA desaturase opposite strand; stearoyl-Coenzyme A desaturase 1; stearoyl-Coenzyme A desaturase 2; stearyl-CoA desaturase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20249, 6319

Content And Storage:
-20°C

Form:
Liquid

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PIPA517333

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Antigen:
PSME3

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P61289, P61290

Gene Symbols:
PSME3

Immunogen:
Synthetic peptide corresponding to residues surrounding Asp16 of human PA2 gamma

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Gene:
PSME3

Gene Alias:
11S regulator complex gamma subunit; 11S regulator complex subunit gamma; AA410043; Ab2-371; Activator of multicatalytic protease subunit 3; AU020960; epididymis secretory protein Li 283; HEL-S-283; Ki; Ki antigen; Ki nuclear autoantigen; PA28 gamma variant 5; pa28g; PA28gamma; PA28-gamma; prosome macropain; proteaseome (prosome, macropain) 28 subunit, 3; proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki); proteasome (prosome, macropain) activator subunit 3; proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki); proteasome activator 28 subunit gamma; proteasome activator 28-gamma; proteasome activator complex subunit 3; proteasome activator subunit 3; Psme3; REG gamma-3; REGgamma; REG-gamma

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10197, 19192, 287716

Content And Storage:
-20°C

Form:
Liquid