PIPA517361

LSD1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA517361-Each-of-1 In Stock ₹ 44,277.30

PIPA517361 - Each of 1

₹ 44,277.30

In Stock

Quantity

1

Base Price: ₹ 44,277.30

GST (18%): ₹ 7,969.914

Total Price: ₹ 52,247.214

Antigen

LSD1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

KDM1A

Gene Alias

1810043O07Rik; AA408884; amine oxidase (flavin containing) domain 2; AOF2; BHC110; BRAF35-HDAC complex protein BHC110; CPRF; D4Ertd478e; FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit; flavin-containing amine oxidase domain-containing protein 2; KDM1; KDM1A; KIAA0601; Lsd1; lysine (K)-specific demethylase 1; lysine (K)-specific demethylase 1A; lysine demethylase 1A; lysine-specific demethylase 1; lysine-specific histone demethylase 1; lysine-specific histone demethylase 1A; mKIAA0601; neuroprotective protein 3; RGD1562975; RP1-184J9.1; wu:fb82e06; wu:fc51a02; wu:fj36a05; wu:fj66b06

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23028, 500569, 99982

Content And Storage

-20°C

Form

Liquid

Applications

ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

19.6 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

O60341, Q6ZQ88

Gene Symbols

KDM1A

Immunogen

Synthetic peptide corresponding to residues near the amino-terminus of human LSD1 protein

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • It is not recommended to aliquot this antibody
  • LSD1 is a histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor
  • LSD1 contains a SWIRM domain, a FAD-binding motif, and an amine oxidase domain
  • This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase
  • It acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed
  • LSD1 demethylates both mono- and tri-methylted 'Lys-4' of histone H3
  • This protein may play a role in the repression of neuronal genes
  • Alone, it is unable to demethylate H3 'Lys-4' on nucleosomes and requires the presence of RCOR1/CoREST to achieve such activity
  • It may also demethylate 'Lys-9' of histone H3, a specific tag for epigenetic transcriptional repression, thereby leading to derepression of androgen receptor target genes
  • Mutations affecting this gene can result in cleft palate, psychomotor retardation, and distintive facial features.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA517361

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Antigen:
LSD1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KDM1A

Gene Alias:
1810043O07Rik; AA408884; amine oxidase (flavin containing) domain 2; AOF2; BHC110; BRAF35-HDAC complex protein BHC110; CPRF; D4Ertd478e; FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit; flavin-containing amine oxidase domain-containing protein 2; KDM1; KDM1A; KIAA0601; Lsd1; lysine (K)-specific demethylase 1; lysine (K)-specific demethylase 1A; lysine demethylase 1A; lysine-specific demethylase 1; lysine-specific histone demethylase 1; lysine-specific histone demethylase 1A; mKIAA0601; neuroprotective protein 3; RGD1562975; RP1-184J9.1; wu:fb82e06; wu:fc51a02; wu:fj36a05; wu:fj66b06

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23028, 500569, 99982

Content And Storage:
-20°C

Form:
Liquid

Applications:
ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
19.6 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
O60341, Q6ZQ88

Gene Symbols:
KDM1A

Immunogen:
Synthetic peptide corresponding to residues near the amino-terminus of human LSD1 protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517366

--


Antigen:
Bim

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BCL2L11

Gene Alias:
1500006F24Rik; BAM; Bcl2 interacting mediator of cell death; bcl-2 interacting mediator of cell death; bcl-2 interacting protein Bim; BCL2 like 11; Bcl-2 like 11; Bcl-2 related apoptotic gene product BimL; bcl2-interacting mediator of cell death; BCL2L11; Bcl2-L-11; BCL2-like 11 (apoptosis facilitator); bcl-2-like protein 11; bcl-2-like protein 11-like; bcl-2-related ovarian death agonist; bcl-2-related ovarian death protein; BIM; Bim EL; Bim-A; BIM-alpha6; BIM-beta6; BIM-beta7; BIMEL; BimEL protein; BimL; BOD; OTTHUMP00000197013; OTTHUMP00000204247; Unknown (protein for MGC:134444)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10018, 12125, 396632, 64547

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
339 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
O43521, O54918, O88498

Gene Symbols:
BCL2L11

Immunogen:
Synthetic peptide corresponding to residues near the amino terminus of human Bim

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517371

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Antigen:
p38 MAPK gamma

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mapk12

Gene Alias:
AW123708; ERK3; ERK5; erk6; ERK-6; etID309866.18; Extracellular signal-regulated kinase 6; fa05c12; LOW QUALITY PROTEIN: mitogen-activated protein kinase 12; mitogen-activated protein kinase 12; MAP kinase 12; MAP kinase p38 gamma; MAPK 12; mapk12; mapk12a; mitogen activated protein kinase 12; mitogen-activated protein kinase 12; mitogen-activated protein kinase 12a; mitogen-activated protein kinase 3; mitogen-activated protein kinase p38 gamma; OTTHUMP00000196671; P38gamma; p38-gamma; Prkm12; SAP kinase-3; sapk3; SAPK-3; stress activated protein kinase 3; stress-activated protein kinase 3; stress-activated protein kinase-3; wu:fa05c12; zgc:101695

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
29857, 60352, 6300

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
O08911, P53778, Q63538

Gene Symbols:
Mapk12

Immunogen:
Synthetic peptide corresponding to the carboxy-terminal residues of human p38 MAPK gamma.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517373

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Antigen:
RAD50

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAD50

Gene Alias:
153 kDa protein; DNA repair protein RAD50; hRad50; hsRAD50; I79_004319; mRad50; Mrell; MRX complex DNA-binding subunit; N0872; NBSLD; Rad50; RAD50 2; RAD50 double strand break repair protein; RAD50 homolog (S. cerevisiae); RAD50 homolog, double strand break repair protein; RAD50 PEN; RAD502; RAD50-2; RAD50-3; Rad50l; YNL250W

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10111

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
Q92878

Gene Symbols:
RAD50

Immunogen:
Synthetic peptide corresponding to residues surrounding Lys713 of human Rad50

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG