PIPA517465

TRADD Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA517465-Each-of-1 In Stock ₹ 41,796.06

PIPA517465 - Each of 1

₹ 41,796.06

In Stock

Quantity

1

Base Price: ₹ 41,796.06

GST (18%): ₹ 7,523.291

Total Price: ₹ 49,319.351

Antigen

TRADD

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TRADD

Gene Alias

9130005N23Rik; AA930854; Hs.89862; Hs89862; MGC11078; TNF receptor 1 associated signal transducer; TNFR1-associated DEATH domain protein; TNFRSF1A associated via death domain; TNFRSF1A-associated via death domain; TRADD; tumor necrosis factor receptor type 1 associated death domain protein; tumor necrosis factor receptor type 1-associated DEATH domain protein; tumor necrosis factor receptor-1-associated protein

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

246756, 71609, 8717

Content And Storage

-20°C

Form

Liquid

Applications

Immunoprecipitation, Western Blot

Concentration

81 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

Q15628, Q3U0V2

Gene Symbols

TRADD

Immunogen

Synthetic peptide corresponding to residues surrounding cysteine 138 of human TRADD

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • It is not recommended to aliquot this antibody
  • TRADD (Tumor necrosis factor receptor type 1-associated DEATH domain protein) is an important mediator of FAS and TNFR1 associated apoptotic signaling
  • The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12
  • TRADD acts by interacting with TRIP12 and leading to the disruption of the interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A
  • TRADD acts as an adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interation with FADD
  • Overexpression of TRADD leads to two major TNF-induced responses - apoptosis and activation of NF-kappa-B.

Compare Similar Items

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Thermo Scientific

PIPA517465

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Antigen:
TRADD

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRADD

Gene Alias:
9130005N23Rik; AA930854; Hs.89862; Hs89862; MGC11078; TNF receptor 1 associated signal transducer; TNFR1-associated DEATH domain protein; TNFRSF1A associated via death domain; TNFRSF1A-associated via death domain; TRADD; tumor necrosis factor receptor type 1 associated death domain protein; tumor necrosis factor receptor type 1-associated DEATH domain protein; tumor necrosis factor receptor-1-associated protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
246756, 71609, 8717

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
81 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
Q15628, Q3U0V2

Gene Symbols:
TRADD

Immunogen:
Synthetic peptide corresponding to residues surrounding cysteine 138 of human TRADD

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA517467

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Antigen:
CD266

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TNFRSF12A

Gene Alias:
AI255180; C87282; CD266; FGF-inducible 14; Fgfrp2; fibroblast growth factor regulated protein 2; fibroblast growth factor-inducible immediate-early response protein 14; Fibroblast growth factor-regulated protein 2; FN14; HPIP; TNF receptor superfamily member 12A; TNFRSF12A; Tumor necrosis factor receptor superfamily member 12A; tumor necrosis factor receptor superfamily, member 12A; TweakR; TWEAK-R; Tweak-receptor; type I transmembrane protein Fn14

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27279, 302965, 51330, 617439

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
197 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
Q9CR75, Q9NP84

Gene Symbols:
TNFRSF12A

Immunogen:
Synthetic peptide corresponding to residues near the carboxy terminus of the TWEAK Receptor/Fn14

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA517468

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Antigen:
SKP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SKP1

Gene Alias:
15kDa; 2610043E24Rik; 2610206H23Rik; cyclin A/CDK2-associated p19; cyclin A/CDK2-associated protein p19; cyclin-A/CDK2-associated protein p19; EMC19; MGC34403; OCP2; OCP-2; OCP-II; OCP-II protein; organ of Corti protein 2; Organ of Corti protein II; p19A; p19Skp1; polypeptide 1-like; RNA polymerase II elongation factor-like protein; RNA polymerase II elongation factor-like protein OCP2; SIII; Skp1; Skp1a; S-phase kinase-associated protein 1; S-phase kinase-associated protein 1A; TCEB1L; transcription elongation factor B polypeptide 1-like

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21402, 287280, 6500

Content And Storage:
-20°C

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P63208, Q6PEC4, Q9WTX5

Gene Symbols:
SKP1, Skp1a

Immunogen:
Synthetic peptide corresponding to residues of human Skp1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA517471

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Antigen:
DVL2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DVL2

Gene Alias:
dishevelled 2; dishevelled 2 (homologous to Drosophila dsh); dishevelled 2, dsh homolog; dishevelled 2, dsh homolog (Drosophila); dishevelled segment polarity protein 2; dishevelled, dsh homolog 2; dishevelled-2; DSH homolog 2; Dvl2; Dvl-2; LOW QUALITY PROTEIN: segment polarity protein dishevelled homolog DVL-2; sb:eu471; Segment polarity protein dishevelled homolog DVL-2; wu:fc05d12; wu:fo71e09; wu:fp54a02; zgc:55372

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100762587, 13543, 1856, 303251

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
201 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
O14641, Q60838

Gene Symbols:
DVL2

Immunogen:
Synthetic peptide corresponding to residues surrounding Ser638 of human Dvl2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Hamster, Human, Mink, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG